Evaluation of polygenic scoring methods in five biobanks shows larger variation between biobanks than methods and finds benefits of ensemble learning.
Monti R, Eick L, Hudjashov G, Läll K, Kanoni S, Wolford BN, Wingfield B, Pain O, Wharrie S, Jermy B, McMahon A, Hartonen T, Heyne H, Mars N, Lambert S; Genes and Health Research Team; Hveem K, Inouye M, van Heel DA, Mägi R, Marttinen P, Ripatti S, Ganna A, Lippert C.
Monti R, et al. Among authors: marttinen p.
Am J Hum Genet. 2024 Jul 11;111(7):1431-1447. doi: 10.1016/j.ajhg.2024.06.003. Epub 2024 Jun 21.
Am J Hum Genet. 2024.
PMID: 38908374