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Page 1
Phage display assisted discovery of a pH-dependent anti-α-cobratoxin antibody from a natural variable domain library.
Tulika T, Pedersen RW, Rimbault C, Ahmadi S, Rivera-de-Torre E, Fernández-Quintero ML, Loeffler JR, Bohn MF, Ljungars A, Ledsgaard L, Voldborg BG, Ruso-Julve F, Andersen JT, Laustsen AH. Tulika T, et al. Among authors: voldborg bg. Protein Sci. 2023 Dec;32(12):e4821. doi: 10.1002/pro.4821. Protein Sci. 2023. PMID: 37897425 Free PMC article.
Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes.
Ledsgaard L, Wade J, Jenkins TP, Boddum K, Oganesyan I, Harrison JA, Villar P, Leah RA, Zenobi R, Schoffelen S, Voldborg B, Ljungars A, McCafferty J, Lomonte B, Gutiérrez JM, Laustsen AH, Karatt-Vellatt A. Ledsgaard L, et al. Nat Commun. 2023 Feb 8;14(1):682. doi: 10.1038/s41467-023-36393-4. Nat Commun. 2023. PMID: 36755049 Free PMC article.
Antibody-dependent enhancement of toxicity of myotoxin II from Bothrops asper.
Sørensen CV, Fernández J, Adams AC, Wildenauer HHK, Schoffelen S, Ledsgaard L, Pucca MB, Fiebig M, Cerni FA, Tulika T, Voldborg BG, Karatt-Vellatt A, Morth JP, Ljungars A, Grav LM, Lomonte B, Laustsen AH. Sørensen CV, et al. Among authors: voldborg bg. Nat Commun. 2024 Jan 16;15(1):173. doi: 10.1038/s41467-023-42624-5. Nat Commun. 2024. PMID: 38228619 Free PMC article.
In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model.
Benard-Valle M, Wouters Y, Ljungars A, Nguyen GTT, Ahmadi S, Ebersole TW, Dahl CH, Guadarrama-Martínez A, Jeppesen F, Eriksen H, Rodríguez-Barrera G, Boddum K, Jenkins TP, Bjørn SP, Schoffelen S, Voldborg BG, Alagón A, Laustsen AH. Benard-Valle M, et al. Among authors: voldborg bg. Nat Commun. 2024 May 21;15(1):4310. doi: 10.1038/s41467-024-48539-z. Nat Commun. 2024. PMID: 38773068 Free PMC article.
Engineering of pH-dependent antigen binding properties for toxin-targeting IgG1 antibodies using light-chain shuffling.
Tulika T, Ruso-Julve F, Ahmadi S, Ljungars A, Rivera-de-Torre E, Wade J, Fernández-Quintero ML, Jenkins TP, Belfakir SB, Ross GMS, Boyens-Thiele L, Buell AK, Sakya SA, Sørensen CV, Bohn MF, Ledsgaard L, Voldborg BG, Francavilla C, Schlothauer T, Lomonte B, Andersen JT, Laustsen AH. Tulika T, et al. Among authors: voldborg bg. Structure. 2024 Sep 5;32(9):1404-1418.e7. doi: 10.1016/j.str.2024.07.014. Epub 2024 Aug 14. Structure. 2024. PMID: 39146931 Free PMC article.
Multiplex genome editing eliminates the Warburg Effect without impacting growth rate in mammalian cells.
Hefzi H, Martínez-Monge I, Marin de Mas I, Cowie NL, Toledo AG, Noh SM, Karottki KJC, Decker M, Arnsdorf J, Camacho-Zaragoza JM, Kol S, Schoffelen S, Pristovšek N, Hansen AH, Miguez AA, Bjorn SP, Brøndum KK, Javidi EM, Jensen KL, Stangl L, Kreidl E, Kallehauge TB, Ley D, Ménard P, Petersen HM, Sukhova Z, Bauer A, Casanova E, Barron N, Malmström J, Nielsen LK, Lee GM, Kildegaard HF, Voldborg BG, Lewis NE. Hefzi H, et al. Among authors: voldborg bg. bioRxiv [Preprint]. 2024 Aug 6:2024.08.02.606284. doi: 10.1101/2024.08.02.606284. bioRxiv. 2024. PMID: 39211256 Free PMC article. Preprint.
Glycoengineered recombinant alpha1-antitrypsin results in comparable in vitro and in vivo activities to human plasma-derived protein.
Rocamora F, Schoffelen S, Arnsdorf J, Toth EA, Abdul Y, Cleveland TE 4th, Bjørn SP, Wu MYM, McElvaney NG, Voldborg BGR, Fuerst TR, Lewis NE. Rocamora F, et al. Among authors: voldborg bgr. bioRxiv [Preprint]. 2024 Mar 30:2024.03.27.587088. doi: 10.1101/2024.03.27.587088. bioRxiv. 2024. PMID: 38585818 Free PMC article. Preprint.
30 results