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Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.
Kim JH, Bugaj LJ, Oh YJ, Bivalacqua TJ, Ryoo S, Soucy KG, Santhanam L, Webb A, Camara A, Sikka G, Nyhan D, Shoukas AA, Ilies M, Christianson DW, Champion HC, Berkowitz DE. Kim JH, et al. Among authors: bugaj lj. J Appl Physiol (1985). 2009 Oct;107(4):1249-57. doi: 10.1152/japplphysiol.91393.2008. Epub 2009 Aug 6. J Appl Physiol (1985). 2009. PMID: 19661445 Free PMC article.
Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism.
Steppan J, Ryoo S, Schuleri KH, Gregg C, Hasan RK, White AR, Bugaj LJ, Khan M, Santhanam L, Nyhan D, Shoukas AA, Hare JM, Berkowitz DE. Steppan J, et al. Among authors: bugaj lj. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4759-64. doi: 10.1073/pnas.0506589103. Epub 2006 Mar 13. Proc Natl Acad Sci U S A. 2006. PMID: 16537391 Free PMC article.
37 results