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Using Constellation Pharmacology to Characterize a Novel α-Conotoxin from Conus ateralbus.
Neves JLB, Urcino C, Chase K, Dowell C, Hone AJ, Morgenstern D, Chua VM, Ramiro IBL, Imperial JS, Leavitt LS, Phan J, Fisher FA, Watkins M, Raghuraman S, Tun JO, Ueberheide BM, McIntosh JM, Vasconcelos V, Olivera BM, Gajewiak J. Neves JLB, et al. Among authors: mcintosh jm. Mar Drugs. 2024 Feb 29;22(3):118. doi: 10.3390/md22030118. Mar Drugs. 2024. PMID: 38535458 Free PMC article.
Conotoxins Targeting Voltage-Gated Sodium Ion Channels.
Pei S, Wang N, Mei Z, Zhangsun D, Craik DJ, McIntosh JM, Zhu X, Luo S. Pei S, et al. Among authors: mcintosh jm. Pharmacol Rev. 2024 Aug 15;76(5):828-845. doi: 10.1124/pharmrev.123.000923. Pharmacol Rev. 2024. PMID: 38914468 Review.
DM506 (3-Methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole fumarate), a Novel Derivative of Ibogamine, Inhibits α7 and α9α10 Nicotinic Acetylcholine Receptors by Different Allosteric Mechanisms.
Tae HS, Ortells MO, Tekarli BJ, Manetti D, Romanelli MN, McIntosh JM, Adams DJ, Arias HR. Tae HS, et al. Among authors: mcintosh jm. ACS Chem Neurosci. 2023 Jul 19;14(14):2537-2547. doi: 10.1021/acschemneuro.3c00212. Epub 2023 Jun 29. ACS Chem Neurosci. 2023. PMID: 37386821
Rapid multi-directed cholinergic transmission in the central nervous system.
Sethuramanujam S, Matsumoto A, deRosenroll G, Murphy-Baum B, Grosman C, McIntosh JM, Jing M, Li Y, Berson D, Yonehara K, Awatramani GB. Sethuramanujam S, et al. Among authors: mcintosh jm. Nat Commun. 2021 Mar 2;12(1):1374. doi: 10.1038/s41467-021-21680-9. Nat Commun. 2021. PMID: 33654091 Free PMC article.
329 results