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Page 1
Mouse genome rewriting and tailoring of three important disease loci.
Zhang W, Golynker I, Brosh R, Fajardo A, Zhu Y, Wudzinska AM, Ordoñez R, Ribeiro-Dos-Santos AM, Carrau L, Damani-Yokota P, Yeung ST, Khairallah C, Vela Gartner A, Chalhoub N, Huang E, Ashe HJ, Khanna KM, Maurano MT, Kim SY, tenOever BR, Boeke JD. Zhang W, et al. Among authors: boeke jd. Nature. 2023 Nov;623(7986):423-431. doi: 10.1038/s41586-023-06675-4. Epub 2023 Nov 1. Nature. 2023. PMID: 37914927 Free PMC article.
GENOME ENGINEERING. The Genome Project-Write.
Boeke JD, Church G, Hessel A, Kelley NJ, Arkin A, Cai Y, Carlson R, Chakravarti A, Cornish VW, Holt L, Isaacs FJ, Kuiken T, Lajoie M, Lessor T, Lunshof J, Maurano MT, Mitchell LA, Rine J, Rosser S, Sanjana NE, Silver PA, Valle D, Wang H, Way JC, Yang L. Boeke JD, et al. Science. 2016 Jul 8;353(6295):126-7. doi: 10.1126/science.aaf6850. Epub 2016 Jun 2. Science. 2016. PMID: 27256881 No abstract available.
Dissection of affinity captured LINE-1 macromolecular complexes.
Taylor MS, Altukhov I, Molloy KR, Mita P, Jiang H, Adney EM, Wudzinska A, Badri S, Ischenko D, Eng G, Burns KH, Fenyö D, Chait BT, Alexeev D, Rout MP, Boeke JD, LaCava J. Taylor MS, et al. Among authors: boeke jd. Elife. 2018 Jan 8;7:e30094. doi: 10.7554/eLife.30094. Elife. 2018. PMID: 29309035 Free PMC article.
Synthetic Genomes.
Zhang W, Mitchell LA, Bader JS, Boeke JD. Zhang W, et al. Among authors: boeke jd. Annu Rev Biochem. 2020 Jun 20;89:77-101. doi: 10.1146/annurev-biochem-013118-110704. Annu Rev Biochem. 2020. PMID: 32569517 Review.
A versatile platform for locus-scale genome rewriting and verification.
Brosh R, Laurent JM, Ordoñez R, Huang E, Hogan MS, Hitchcock AM, Mitchell LA, Pinglay S, Cadley JA, Luther RD, Truong DM, Boeke JD, Maurano MT. Brosh R, et al. Among authors: boeke jd. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2023952118. doi: 10.1073/pnas.2023952118. Proc Natl Acad Sci U S A. 2021. PMID: 33649239 Free PMC article.
De novo assembly and delivery to mouse cells of a 101 kb functional human gene.
Mitchell LA, McCulloch LH, Pinglay S, Berger H, Bosco N, Brosh R, Bulajić M, Huang E, Hogan MS, Martin JA, Mazzoni EO, Davoli T, Maurano MT, Boeke JD. Mitchell LA, et al. Among authors: boeke jd. Genetics. 2021 May 17;218(1):iyab038. doi: 10.1093/genetics/iyab038. Genetics. 2021. PMID: 33742653 Free PMC article.
422 results