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Page 1
A molecular signature for IL-10-producing Th1 cells in protozoan parasitic diseases.
Edwards CL, Engel JA, de Labastida Rivera F, Ng SS, Corvino D, Montes de Oca M, Frame TC, Chauhan SB, Singh SS, Kumar A, Wang Y, Na J, Mukhopadhyay P, Lee JS, Nylen S, Sundar S, Kumar R, Engwerda CR. Edwards CL, et al. Among authors: frame tc. JCI Insight. 2023 Dec 22;8(24):e169362. doi: 10.1172/jci.insight.169362. JCI Insight. 2023. PMID: 37917177 Free PMC article.
IL-17A-Producing γδ T Cells Suppress Early Control of Parasite Growth by Monocytes in the Liver.
Sheel M, Beattie L, Frame TC, de Labastida Rivera F, Faleiro RJ, Bunn PT, Montes de Oca M, Edwards CL, Ng SS, Kumar R, Amante FH, Best SE, McColl SR, Varelias A, Kuns RD, MacDonald KP, Smyth MJ, Haque A, Hill GR, Engwerda CR. Sheel M, et al. Among authors: frame tc. J Immunol. 2015 Dec 15;195(12):5707-17. doi: 10.4049/jimmunol.1501046. Epub 2015 Nov 4. J Immunol. 2015. PMID: 26538396
Bone marrow-derived and resident liver macrophages display unique transcriptomic signatures but similar biological functions.
Beattie L, Sawtell A, Mann J, Frame TCM, Teal B, de Labastida Rivera F, Brown N, Walwyn-Brown K, Moore JWJ, MacDonald S, Lim EK, Dalton JE, Engwerda CR, MacDonald KP, Kaye PM. Beattie L, et al. Among authors: frame tcm. J Hepatol. 2016 Oct;65(4):758-768. doi: 10.1016/j.jhep.2016.05.037. Epub 2016 Jun 1. J Hepatol. 2016. PMID: 27262757 Free PMC article.
Rapid loss of group 1 innate lymphoid cells during blood stage Plasmodium infection.
Ng SS, Souza-Fonseca-Guimaraes F, Rivera FL, Amante FH, Kumar R, Gao Y, Sheel M, Beattie L, Montes de Oca M, Guillerey C, Edwards CL, Faleiro RJ, Frame T, Bunn PT, Vivier E, Godfrey DI, Pellicci DG, Lopez JA, Andrews KT, Huntington ND, Smyth MJ, McCarthy J, Engwerda CR. Ng SS, et al. Clin Transl Immunology. 2018 Jan 12;7(1):e1003. doi: 10.1002/cti2.1003. eCollection 2018. Clin Transl Immunology. 2018. PMID: 29484181 Free PMC article.
Distinct Roles for CD4+ Foxp3+ Regulatory T Cells and IL-10-Mediated Immunoregulatory Mechanisms during Experimental Visceral Leishmaniasis Caused by Leishmania donovani.
Bunn PT, Montes de Oca M, de Labastida Rivera F, Kumar R, Ng SS, Edwards CL, Faleiro RJ, Sheel M, Amante FH, Frame TCM, Muller W, Haque A, Uzonna JE, Hill GR, Engwerda CR. Bunn PT, et al. Among authors: frame tcm. J Immunol. 2018 Dec 1;201(11):3362-3372. doi: 10.4049/jimmunol.1701582. Epub 2018 Oct 24. J Immunol. 2018. PMID: 30355785
Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis.
Kumar R, Bunn PT, Singh SS, Ng SS, Montes de Oca M, De Labastida Rivera F, Chauhan SB, Singh N, Faleiro RJ, Edwards CL, Frame TCM, Sheel M, Austin RJ, Lane SW, Bald T, Smyth MJ, Hill GR, Best SE, Haque A, Corvino D, Waddell N, Koufariotis L, Mukhopadhay P, Rai M, Chakravarty J, Singh OP, Sacks D, Nylen S, Uzonna J, Sundar S, Engwerda CR. Kumar R, et al. Among authors: frame tcm. Cell Rep. 2020 Feb 25;30(8):2512-2525.e9. doi: 10.1016/j.celrep.2020.01.099. Cell Rep. 2020. PMID: 32101732 Free PMC article.
The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation.
Ng SS, De Labastida Rivera F, Yan J, Corvino D, Das I, Zhang P, Kuns R, Chauhan SB, Hou J, Li XY, Frame TCM, McEnroe BA, Moore E, Na J, Engel JA, Soon MSF, Singh B, Kueh AJ, Herold MJ, Montes de Oca M, Singh SS, Bunn PT, Aguilera AR, Casey M, Braun M, Ghazanfari N, Wani S, Wang Y, Amante FH, Edwards CL, Haque A, Dougall WC, Singh OP, Baxter AG, Teng MWL, Loukas A, Daly NL, Cloonan N, Degli-Esposti MA, Uzonna J, Heath WR, Bald T, Tey SK, Nakamura K, Hill GR, Kumar R, Sundar S, Smyth MJ, Engwerda CR. Ng SS, et al. Among authors: frame tcm. Nat Immunol. 2020 Oct;21(10):1205-1218. doi: 10.1038/s41590-020-0758-6. Epub 2020 Aug 24. Nat Immunol. 2020. PMID: 32839608 Free PMC article.
IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection.
Montes de Oca M, de Labastida Rivera F, Winterford C, Frame TCM, Ng SS, Amante FH, Edwards CL, Bukali L, Wang Y, Uzonna JE, Kuns RD, Zhang P, Kabat A, Klein Geltink RI, Pearce EJ, Hill GR, Engwerda CR. Montes de Oca M, et al. Among authors: frame tcm. PLoS Pathog. 2020 Oct 13;16(10):e1008994. doi: 10.1371/journal.ppat.1008994. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33049000 Free PMC article.
IL-10-producing Th1 cells possess a distinct molecular signature in malaria.
Edwards CL, Ng SS, de Labastida Rivera F, Corvino D, Engel JA, Montes de Oca M, Bukali L, Frame TC, Bunn PT, Chauhan SB, Singh SS, Wang Y, Na J, Amante FH, Loughland JR, Soon MS, Waddell N, Mukhopadhay P, Koufariotis LT, Johnston RL, Lee JS, Kuns R, Zhang P, Boyle MJ, Hill GR, McCarthy JS, Kumar R, Engwerda CR. Edwards CL, et al. Among authors: frame tc. J Clin Invest. 2023 Jan 3;133(1):e153733. doi: 10.1172/JCI153733. J Clin Invest. 2023. PMID: 36594463 Free PMC article.
IL-10-producing Th1 cells possess a distinct molecular signature in malaria.
Edwards CL, Ng SS, de Labastida Rivera F, Corvino D, Engel JA, Montes de Oca M, Bukali L, Frame TC, Bunn PT, Chauhan SB, Singh SS, Wang Y, Na J, Amante FH, Loughland JR, Soon MS, Waddell N, Mukhopadhay P, Koufariotis LT, Johnston RL, Lee JS, Kuns R, Zhang P, Boyle MJ, Hill GR, McCarthy JS, Kumar R, Engwerda CR. Edwards CL, et al. Among authors: frame tc. J Clin Invest. 2023 Feb 15;133(4):e169299. doi: 10.1172/JCI169299. J Clin Invest. 2023. PMID: 36787259 Free PMC article. No abstract available.
12 results