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Restoring the Multiple Sclerosis Associated Imbalance of Gut Indole Metabolites Promotes Remyelination and Suppresses Neuroinflammation.
Jank L, Singh SS, Lee J, Dhukhwa A, Siavoshi F, Joshi D, Minney V, Gupta K, Ghimire S, Deme P, Schoeps VA, Soman K, Ladakis D, Smith M, Borkowski K, Newman J, Baranzini SE, Waubant EL, Fitzgerald KC, Mangalam A, Haughey N, Kornberg M, Chamling X, Calabresi PA, Bhargava P. Jank L, et al. Among authors: singh ss. bioRxiv [Preprint]. 2024 Oct 28:2024.10.27.620437. doi: 10.1101/2024.10.27.620437. bioRxiv. 2024. PMID: 39554063 Free PMC article. Preprint.
Fatty acid derivatization and cyclization of the immunomodulatory peptide RP-182 targeting CD206high macrophages improves anti-tumor activity.
Singh SS, Calvo R, Kumari A, Sable RV, Fang Y, Tao D, Hu X, Castle SG, Nahar S, Li D, Major E, Sanchez TW, Kato R, Xu X, Zhou J, Liu L, LeClair CA, Simeonov A, Baljinnyam B, Henderson MJ, Marugan J, Rudloff U. Singh SS, et al. Mol Cancer Ther. 2024 Aug 30. doi: 10.1158/1535-7163.MCT-23-0790. Online ahead of print. Mol Cancer Ther. 2024. PMID: 39212669
Ammonia transporter RhBG initiates downstream signaling and functional responses by activating NFκB.
Mishra S, Welch N, Singh SS, Singh KD, Bellar A, Kumar A, Deutz LN, Hanlon MD, Kant S, Dastidar S, Patel H, Agrawal V, Attaway AH, Musich R, Stark GR, Tedesco FS, Truskey GA, Weiner ID, Karnik SS, Dasarathy S. Mishra S, et al. Among authors: singh ss. Proc Natl Acad Sci U S A. 2024 Jul 30;121(31):e2314760121. doi: 10.1073/pnas.2314760121. Epub 2024 Jul 25. Proc Natl Acad Sci U S A. 2024. PMID: 39052834
642 results