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Distinct use of super-enhancer elements controls cell type-specific CD25 transcription and function.
Spolski R, Li P, Chandra V, Shin B, Goel S, Sakamoto K, Liu C, Oh J, Ren M, Enomoto Y, West EE, Christensen SM, Wan ECK, Ge M, Lin JX, Yan B, Kazemian M, Yu ZX, Nagao K, Vijayanand P, Rothenberg EV, Leonard WJ. Spolski R, et al. Among authors: chandra v. Sci Immunol. 2023 Nov 3;8(89):eadi8217. doi: 10.1126/sciimmunol.adi8217. Epub 2023 Nov 3. Sci Immunol. 2023. PMID: 37922339 Free PMC article.
Single-cell eQTL analysis of activated T cell subsets reveals activation and cell type-dependent effects of disease-risk variants.
Schmiedel BJ, Gonzalez-Colin C, Fajardo V, Rocha J, Madrigal A, Ramírez-Suástegui C, Bhattacharyya S, Simon H, Greenbaum JA, Peters B, Seumois G, Ay F, Chandra V, Vijayanand P. Schmiedel BJ, et al. Among authors: chandra v. Sci Immunol. 2022 Feb 25;7(68):eabm2508. doi: 10.1126/sciimmunol.abm2508. Epub 2022 Feb 25. Sci Immunol. 2022. PMID: 35213211 Free PMC article.
JAML immunotherapy targets recently activated tumor-infiltrating CD8+ T cells.
Eschweiler S, Wang A, Ramírez-Suástegui C, von Witzleben A, Li Y, Chee SJ, Simon H, Mondal M, Ellis M, Thomas GJ, Chandra V, Ottensmeier CH, Vijayanand P. Eschweiler S, et al. Among authors: chandra v. Cell Rep. 2023 Feb 28;42(2):112040. doi: 10.1016/j.celrep.2023.112040. Epub 2023 Jan 25. Cell Rep. 2023. PMID: 36701231 Free PMC article.
COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types.
Schmiedel BJ, Chandra V, Rocha J, Gonzalez-Colin C, Bhattacharyya S, Madrigal A, Ottensmeier CH, Ay F, Vijayanand P. Schmiedel BJ, et al. Among authors: chandra v. bioRxiv [Preprint]. 2020 Dec 2:2020.12.01.407429. doi: 10.1101/2020.12.01.407429. bioRxiv. 2020. Update in: Nat Commun. 2021 Nov 19;12(1):6760. doi: 10.1038/s41467-021-26888-3 PMID: 33299987 Free PMC article. Updated. Preprint.
524 results