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ASK family proteins in stress response and disease.
Fujisawa T, Takeda K, Ichijo H. Fujisawa T, et al. Among authors: ichijo h. Mol Biotechnol. 2007 Sep;37(1):13-8. doi: 10.1007/s12033-007-0053-x. Mol Biotechnol. 2007. PMID: 17914158 Review.
A systematic immunoprecipitation approach reinforces the concept of common conformational alterations in amyotrophic lateral sclerosis-linked SOD1 mutants.
Fujisawa T, Yamaguchi N, Kadowaki H, Tsukamoto Y, Tsuburaya N, Tsubota A, Takahashi H, Naguro I, Takahashi Y, Goto J, Tsuji S, Nishitoh H, Homma K, Ichijo H. Fujisawa T, et al. Among authors: ichijo h. Neurobiol Dis. 2015 Oct;82:478-486. doi: 10.1016/j.nbd.2015.08.010. Epub 2015 Aug 18. Neurobiol Dis. 2015. PMID: 26297318
The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.
Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H. Imamura K, et al. Among authors: ichijo h. Sci Transl Med. 2017 May 24;9(391):eaaf3962. doi: 10.1126/scitranslmed.aaf3962. Sci Transl Med. 2017. PMID: 28539470 Free article.
A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model.
Tsuburaya N, Homma K, Higuchi T, Balia A, Yamakoshi H, Shibata N, Nakamura S, Nakagawa H, Ikeda SI, Umezawa N, Kato N, Yokoshima S, Shibuya M, Shimonishi M, Kojima H, Okabe T, Nagano T, Naguro I, Imamura K, Inoue H, Fujisawa T, Ichijo H. Tsuburaya N, et al. Among authors: ichijo h. Nat Commun. 2018 Jul 10;9(1):2668. doi: 10.1038/s41467-018-05127-2. Nat Commun. 2018. PMID: 29991716 Free PMC article.
371 results