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Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.
Boby ML, Fearon D, Ferla M, Filep M, Koekemoer L, Robinson MC; COVID Moonshot Consortium‡; Chodera JD, Lee AA, London N, von Delft A, von Delft F, Achdout H, Aimon A, Alonzi DS, Arbon R, Aschenbrenner JC, Balcomb BH, Bar-David E, Barr H, Ben-Shmuel A, Bennett J, Bilenko VA, Borden B, Boulet P, Bowman GR, Brewitz L, Brun J, Bvnbs S, Calmiano M, Carbery A, Carney DW, Cattermole E, Chang E, Chernyshenko E, Clyde A, Coffland JE, Cohen G, Cole JC, Contini A, Cox L, Croll TI, Cvitkovic M, De Jonghe S, Dias A, Donckers K, Dotson DL, Douangamath A, Duberstein S, Dudgeon T, Dunnett LE, Eastman P, Erez N, Eyermann CJ, Fairhead M, Fate G, Fedorov O, Fernandes RS, Ferrins L, Foster R, Foster H, Fraisse L, Gabizon R, García-Sastre A, Gawriljuk VO, Gehrtz P, Gileadi C, Giroud C, Glass WG, Glen RC, Glinert I, Godoy AS, Gorichko M, Gorrie-Stone T, Griffen EJ, Haneef A, Hassell Hart S, Heer J, Henry M, Hill M, Horrell S, Huang QYJ, Huliak VD, Hurley MFD, Israely T, Jajack A, Jansen J, Jnoff E, Jochmans D, John T, Kaminow B, Kang L, Kantsadi AL, Kenny PW, Kiappes JL, Kinakh SO, Kovar B, Krojer T, La VNT, Laghnimi-Hahn S, Lefker BA, Levy H, Lithgo RM, Logvinenko IG, Lukacik P, Macdonald HB, M… See abstract for full author list ➔ Boby ML, et al. Among authors: fraisse l. Science. 2023 Nov 10;382(6671):eabo7201. doi: 10.1126/science.abo7201. Epub 2023 Nov 10. Science. 2023. PMID: 37943932 Free PMC article.
Correction: Facing the escalating burden of dengue: Challenges and perspectives.
Malavige GN, Sjö P, Singh K, Piedagnel JM, Mowbray C, Estani S, Lim SCL, Siqueira AM, Ogg GS, Fraisse L, Ribeiro I. Malavige GN, et al. Among authors: fraisse l. PLOS Glob Public Health. 2024 Jul 9;4(7):e0003499. doi: 10.1371/journal.pgph.0003499. eCollection 2024. PLOS Glob Public Health. 2024. PMID: 38980843 Free PMC article.
Further preclinical characterization of molnupiravir against SARS-CoV-2: Antiviral activity determinants and viral genome alteration patterns.
Petit PR, Touret F, Driouich JS, Cochin M, Luciani L, Bernadin O, Laprie C, Piorkowski G, Fraisse L, Sjö P, Mowbray CE, Escudié F, Scandale I, Chatelain E, de Lamballerie X, Solas C, Nougairède A. Petit PR, et al. Among authors: fraisse l. Heliyon. 2024 May 8;10(10):e30862. doi: 10.1016/j.heliyon.2024.e30862. eCollection 2024 May 30. Heliyon. 2024. PMID: 38803975 Free PMC article.
Generation and evaluation of protease inhibitor-resistant SARS-CoV-2 strains.
Bouzidi HS, Driouich JS, Klitting R, Bernadin O, Piorkowski G, Amaral R, Fraisse L, Mowbray CE, Scandale I, Escudié F, Chatelain E, de Lamballerie X, Nougairède A, Touret F. Bouzidi HS, et al. Among authors: fraisse l. Antiviral Res. 2024 Feb;222:105814. doi: 10.1016/j.antiviral.2024.105814. Epub 2024 Jan 24. Antiviral Res. 2024. PMID: 38272321 Free article.
Facing the escalating burden of dengue: Challenges and perspectives.
Malavige GN, Sjö P, Singh K, Piedagnel JM, Mowbray C, Estani S, Lim SCL, Siquierra AM, Ogg GS, Fraisse L, Ribeiro I. Malavige GN, et al. Among authors: fraisse l. PLOS Glob Public Health. 2023 Dec 15;3(12):e0002598. doi: 10.1371/journal.pgph.0002598. eCollection 2023. PLOS Glob Public Health. 2023. PMID: 38100392 Free PMC article. Review.
Combinatorial Regimens Augment Drug Monotherapy for SARS-CoV-2 Clearance in Mice.
Ullah I, Escudie F, Scandale I, Gilani Z, Gendron-Lepage G, Gaudette F, Mowbray C, Fraisse L, Bazin R, Finzi A, Mothes W, Kumar P, Chatelain E, Uchil PD. Ullah I, et al. Among authors: fraisse l. bioRxiv [Preprint]. 2023 Jun 1:2023.05.31.543159. doi: 10.1101/2023.05.31.543159. bioRxiv. 2023. Update in: iScience. 2024 Jan 30;27(3):109049. doi: 10.1016/j.isci.2024.109049 PMID: 37398307 Free PMC article. Updated. Preprint.
49 results