Pang A - Search Results

1

Discovery of a potent and selective PARP1 degrader promoting cell cycle arrest via intercepting CDC25C-CDK1 axis for treating triple-negative breast cancer.

Wu Y, Wu M, Zheng X, Yu H, Mao X, Jin Y, Wang Y, Pang A, Zhang J, Zeng S, Xu T, Chen Y, Zhang B, Lin N, Dai H, Wang Y, Yao X, Dong X, Huang W, Che J. Wu Y, et al. Among authors: pang a. Bioorg Chem. 2024 Jan;142:106952. doi: 10.1016/j.bioorg.2023.106952. Epub 2023 Nov 8. Bioorg Chem. 2024. PMID: 37952486

2

Structural Feature Analyzation Strategies toward Discovery of Orally Bioavailable PROTACs of Bruton's Tyrosine Kinase for the Treatment of Lymphoma.

Zhang J, Che J, Luo X, Wu M, Kan W, Jin Y, Wang H, Pang A, Li C, Huang W, Zeng S, Zhuang W, Wu Y, Xu Y, Zhou Y, Li J, Dong X. Zhang J, et al. Among authors: pang a. J Med Chem. 2022 Jul 14;65(13):9096-9125. doi: 10.1021/acs.jmedchem.2c00324. Epub 2022 Jun 7. J Med Chem. 2022. PMID: 35671249

3

Advances of targeting the YAP/TAZ-TEAD complex in the hippo pathway for the treatment of cancers.

Luo M, Xu Y, Chen H, Wu Y, Pang A, Hu J, Dong X, Che J, Yang H. Luo M, et al. Among authors: pang a. Eur J Med Chem. 2022 Dec 15;244:114847. doi: 10.1016/j.ejmech.2022.114847. Epub 2022 Oct 13. Eur J Med Chem. 2022. PMID: 36265280 Review.

4

Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological Tumors.

Duan H, Zhang J, Gui R, Lu Y, Pang A, Chen B, Shen L, Yu H, Li J, Xu T, Wang Y, Yao X, Zhang B, Lin N, Dong X, Zhou Y, Che J. Duan H, et al. Among authors: pang a. J Med Chem. 2024 Jul 11;67(13):11326-11353. doi: 10.1021/acs.jmedchem.4c00883. Epub 2024 Jun 24. J Med Chem. 2024. PMID: 38913763

5

Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia.

Zhang J, Duan H, Gui R, Wu M, Shen L, Jin Y, Pang A, Yu X, Zeng S, Zhang B, Lin N, Huang W, Wang Y, Yao X, Li J, Dong X, Zhou Y, Che J. Zhang J, et al. Among authors: pang a. Eur J Med Chem. 2023 Oct 17;262:115872. doi: 10.1016/j.ejmech.2023.115872. Online ahead of print. Eur J Med Chem. 2023. PMID: 39491427

6

On-Resin Synthesis of Linear Aryl Thioether Containing Peptides and in-Solution Cyclization via Cysteine S_NAr Reaction.

Li J, Lai W, Pang A, Liu L, Ye L, Xiong XF. Li J, et al. Among authors: pang a. Org Lett. 2022 Mar 4;24(8):1673-1677. doi: 10.1021/acs.orglett.2c00234. Epub 2022 Feb 23. Org Lett. 2022. PMID: 35195423

7

Informed consent and risk communication challenges in antimicrobial clinical trials: a scoping review.

Shou Y, Yeo JE, Pang AS, Paterson DL, Mo Y. Shou Y, et al. Among authors: pang as. BMJ Open. 2024 Nov 24;14(11):e082096. doi: 10.1136/bmjopen-2023-082096. BMJ Open. 2024. PMID: 39581733 Free PMC article. Review.

8

DNA methylation age from peripheral blood predicts progression to Alzheimer's disease, white matter disease burden, and cortical atrophy.

Bonham L, Sirkis D, Pang A, Sugrue L, Santamaría-García H, Ibanez A, Miller B, Yokoyama J, Corley M. Bonham L, et al. Among authors: pang a. Res Sq [Preprint]. 2024 Oct 28:rs.3.rs-5273529. doi: 10.21203/rs.3.rs-5273529/v1. Res Sq. 2024. PMID: 39574903 Free PMC article. Preprint.

9

Discovery of a single-subunit oligosaccharyltransferase that enables glycosylation of full-length IgG antibodies in Escherichia coli.

Sotomayor B, Donahue TC, Mahajan SP, Taw MN, Hulbert SW, Bidstrup EJ, Owitipana DN, Pang A, Yang X, Ghosal S, Alabi CA, Azadi P, Gray JJ, Jewett MC, Wang LX, DeLisa MP. Sotomayor B, et al. Among authors: pang a. bioRxiv [Preprint]. 2024 Nov 10:2024.08.12.607630. doi: 10.1101/2024.08.12.607630. bioRxiv. 2024. PMID: 39574765 Free PMC article. Preprint.

10

Multimodal neuroimaging-based prediction of Parkinson's disease with mild cognitive impairment using machine learning technique.

Zhu Y, Wang F, Ning P, Zhu Y, Zhang L, Li K, Liu B, Ren H, Xu Z, Pang A, Yang X. Zhu Y, et al. Among authors: pang a. NPJ Parkinsons Dis. 2024 Nov 11;10(1):218. doi: 10.1038/s41531-024-00828-6. NPJ Parkinsons Dis. 2024. PMID: 39528560 Free PMC article.

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