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Mitigating risk in academic preclinical drug discovery.
Dahlin JL, Inglese J, Walters MA. Dahlin JL, et al. Among authors: inglese j. Nat Rev Drug Discov. 2015 Apr;14(4):279-94. doi: 10.1038/nrd4578. Nat Rev Drug Discov. 2015. PMID: 25829283 Free PMC article. Review.
High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations.
Mott BT, Eastman RT, Guha R, Sherlach KS, Siriwardana A, Shinn P, McKnight C, Michael S, Lacerda-Queiroz N, Patel PR, Khine P, Sun H, Kasbekar M, Aghdam N, Fontaine SD, Liu D, Mierzwa T, Mathews-Griner LA, Ferrer M, Renslo AR, Inglese J, Yuan J, Roepe PD, Su XZ, Thomas CJ. Mott BT, et al. Among authors: inglese j. Sci Rep. 2015 Sep 25;5:13891. doi: 10.1038/srep13891. Sci Rep. 2015. PMID: 26403635 Free PMC article.
Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts.
Cheng KC, Cao S, Raveh A, MacArthur R, Dranchak P, Chlipala G, Okoneski MT, Guha R, Eastman RT, Yuan J, Schultz PJ, Su XZ, Tamayo-Castillo G, Matainaho T, Clardy J, Sherman DH, Inglese J. Cheng KC, et al. Among authors: inglese j. J Nat Prod. 2015 Oct 23;78(10):2411-22. doi: 10.1021/acs.jnatprod.5b00489. Epub 2015 Oct 14. J Nat Prod. 2015. PMID: 26465675 Free PMC article.
Genome-Edited Cell Lines for High-Throughput Screening.
Dranchak P, Moran JJ, MacArthur R, Lopez-Anido C, Inglese J, Svaren J. Dranchak P, et al. Among authors: inglese j. Methods Mol Biol. 2018;1755:1-17. doi: 10.1007/978-1-4939-7724-6_1. Methods Mol Biol. 2018. PMID: 29671259 Free PMC article.
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Solinski HJ, Dranchak P, Oliphant E, Gu X, Earnest TW, Braisted J, Inglese J, Hoon MA. Solinski HJ, et al. Among authors: inglese j. Sci Transl Med. 2019 Jul 10;11(500):eaav5464. doi: 10.1126/scitranslmed.aav5464. Sci Transl Med. 2019. PMID: 31292265 Free PMC article.
198 results