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Omics data integration suggests a potential idiopathic Parkinson's disease signature.
Zagare A, Preciat G, Nickels SL, Luo X, Monzel AS, Gomez-Giro G, Robertson G, Jaeger C, Sharif J, Koseki H, Diederich NJ, Glaab E, Fleming RMT, Schwamborn JC. Zagare A, et al. Among authors: monzel as. Commun Biol. 2023 Nov 20;6(1):1179. doi: 10.1038/s42003-023-05548-w. Commun Biol. 2023. PMID: 37985891 Free PMC article.
Machine learning-assisted neurotoxicity prediction in human midbrain organoids.
Monzel AS, Hemmer K, Kaoma T, Smits LM, Bolognin S, Lucarelli P, Rosety I, Zagare A, Antony P, Nickels SL, Krueger R, Azuaje F, Schwamborn JC. Monzel AS, et al. Parkinsonism Relat Disord. 2020 Jun;75:105-109. doi: 10.1016/j.parkreldis.2020.05.011. Epub 2020 May 8. Parkinsonism Relat Disord. 2020. PMID: 32534431 Free article.
A robust protocol for the generation of human midbrain organoids.
Zagare A, Gobin M, Monzel AS, Schwamborn JC. Zagare A, et al. Among authors: monzel as. STAR Protoc. 2021 May 4;2(2):100524. doi: 10.1016/j.xpro.2021.100524. eCollection 2021 Jun 18. STAR Protoc. 2021. PMID: 34027482 Free PMC article.
Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells.
Monzel AS, Smits LM, Hemmer K, Hachi S, Moreno EL, van Wuellen T, Jarazo J, Walter J, Brüggemann I, Boussaad I, Berger E, Fleming RMT, Bolognin S, Schwamborn JC. Monzel AS, et al. Stem Cell Reports. 2017 May 9;8(5):1144-1154. doi: 10.1016/j.stemcr.2017.03.010. Epub 2017 Apr 13. Stem Cell Reports. 2017. PMID: 28416282 Free PMC article.
Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality.
Walter J, Bolognin S, Antony PMA, Nickels SL, Poovathingal SK, Salamanca L, Magni S, Perfeito R, Hoel F, Qing X, Jarazo J, Arias-Fuenzalida J, Ignac T, Monzel AS, Gonzalez-Cano L, Pereira de Almeida L, Skupin A, Tronstad KJ, Schwamborn JC. Walter J, et al. Among authors: monzel as. Stem Cell Reports. 2019 May 14;12(5):878-889. doi: 10.1016/j.stemcr.2019.03.004. Epub 2019 Apr 11. Stem Cell Reports. 2019. PMID: 30982740 Free PMC article.
Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2-Hydroxypropyl-β-Cyclodextrin Treatment.
Jarazo J, Barmpa K, Modamio J, Saraiva C, Sabaté-Soler S, Rosety I, Griesbeck A, Skwirblies F, Zaffaroni G, Smits LM, Su J, Arias-Fuenzalida J, Walter J, Gomez-Giro G, Monzel AS, Qing X, Vitali A, Cruciani G, Boussaad I, Brunelli F, Jäger C, Rakovic A, Li W, Yuan L, Berger E, Arena G, Bolognin S, Schmidt R, Schröder C, Antony PMA, Klein C, Krüger R, Seibler P, Schwamborn JC. Jarazo J, et al. Among authors: monzel as. Mov Disord. 2022 Jan;37(1):80-94. doi: 10.1002/mds.28810. Epub 2021 Oct 12. Mov Disord. 2022. PMID: 34637165 Free PMC article.
Treating Parkinson's Disease with Human Bone Marrow Mesenchymal Stem Cell Secretome: A Translational Investigation Using Human Brain Organoids and Different Routes of In Vivo Administration.
Mendes-Pinheiro B, Campos J, Marote A, Soares-Cunha C, Nickels SL, Monzel AS, Cibrão JR, Loureiro-Campos E, Serra SC, Barata-Antunes S, Duarte-Silva S, Pinto L, Schwamborn JC, Salgado AJ. Mendes-Pinheiro B, et al. Among authors: monzel as. Cells. 2023 Nov 2;12(21):2565. doi: 10.3390/cells12212565. Cells. 2023. PMID: 37947643 Free PMC article.
The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1.
Walter J, Bolognin S, Poovathingal SK, Magni S, Gérard D, Antony PMA, Nickels SL, Salamanca L, Berger E, Smits LM, Grzyb K, Perfeito R, Hoel F, Qing X, Ohnmacht J, Bertacchi M, Jarazo J, Ignac T, Monzel AS, Gonzalez-Cano L, Krüger R, Sauter T, Studer M, de Almeida LP, Tronstad KJ, Sinkkonen L, Skupin A, Schwamborn JC. Walter J, et al. Among authors: monzel as. Cell Rep. 2021 Oct 19;37(3):109864. doi: 10.1016/j.celrep.2021.109864. Cell Rep. 2021. PMID: 34686322 Free article.
28 results