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Phosphoproteomics of patient-derived xenografts identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer.
Beekhof R, Bertotti A, Böttger F, Vurchio V, Cottino F, Zanella ER, Migliardi G, Viviani M, Grassi E, Lupo B, Henneman AA, Knol JC, Pham TV, de Goeij-de Haas R, Piersma SR, Labots M, Verheul HMW, Trusolino L, Jimenez CR. Beekhof R, et al. Among authors: bottger f. Sci Transl Med. 2023 Aug 16;15(709):eabm3687. doi: 10.1126/scitranslmed.abm3687. Epub 2023 Aug 16. Sci Transl Med. 2023. PMID: 37585503 Free article.
Secreted protein markers in oral squamous cell carcinoma (OSCC).
Mumtaz M, Bijnsdorp IV, Böttger F, Piersma SR, Pham TV, Mumtaz S, Brakenhoff RH, Akhtar MW, Jimenez CR. Mumtaz M, et al. Among authors: bottger f. Clin Proteomics. 2022 Feb 8;19(1):4. doi: 10.1186/s12014-022-09341-5. Clin Proteomics. 2022. PMID: 35130834 Free PMC article.
Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells.
Glykofridis IE, Knol JC, Balk JA, Westland D, Pham TV, Piersma SR, Lougheed SM, Derakhshan S, Veen P, Rooimans MA, van Mil SE, Böttger F, Poddighe PJ, van de Beek I, Drost J, Zwartkruis FJ, de Menezes RX, Meijers-Heijboer HE, Houweling AC, Jimenez CR, Wolthuis RM. Glykofridis IE, et al. Among authors: bottger f. Elife. 2021 Jan 18;10:e61630. doi: 10.7554/eLife.61630. Elife. 2021. PMID: 33459596 Free PMC article.
DPHL: A DIA Pan-human Protein Mass Spectrometry Library for Robust Biomarker Discovery.
Zhu T, Zhu Y, Xuan Y, Gao H, Cai X, Piersma SR, Pham TV, Schelfhorst T, Haas RRGD, Bijnsdorp IV, Sun R, Yue L, Ruan G, Zhang Q, Hu M, Zhou Y, Van Houdt WJ, Le Large TYS, Cloos J, Wojtuszkiewicz A, Koppers-Lalic D, Böttger F, Scheepbouwer C, Brakenhoff RH, van Leenders GJLH, Ijzermans JNM, Martens JWM, Steenbergen RDM, Grieken NC, Selvarajan S, Mantoo S, Lee SS, Yeow SJY, Alkaff SMF, Xiang N, Sun Y, Yi X, Dai S, Liu W, Lu T, Wu Z, Liang X, Wang M, Shao Y, Zheng X, Xu K, Yang Q, Meng Y, Lu C, Zhu J, Zheng J, Wang B, Lou S, Dai Y, Xu C, Yu C, Ying H, Lim TK, Wu J, Gao X, Luan Z, Teng X, Wu P, Huang S, Tao Z, Iyer NG, Zhou S, Shao W, Lam H, Ma D, Ji J, Kon OL, Zheng S, Aebersold R, Jimenez CR, Guo T. Zhu T, et al. Among authors: bottger f. Genomics Proteomics Bioinformatics. 2020 Apr;18(2):104-119. doi: 10.1016/j.gpb.2019.11.008. Epub 2020 Aug 12. Genomics Proteomics Bioinformatics. 2020. PMID: 32795611 Free PMC article.
Swift Large-scale Examination of Directed Genome Editing.
Hammouda OT, Böttger F, Wittbrodt J, Thumberger T. Hammouda OT, et al. Among authors: bottger f. PLoS One. 2019 Mar 5;14(3):e0213317. doi: 10.1371/journal.pone.0213317. eCollection 2019. PLoS One. 2019. PMID: 30835740 Free PMC article.
20 results