Bennett F - Search Results

1

G₂C₄ targeting antisense oligonucleotides potently mitigate TDP-43 dysfunction in human C9orf72 ALS/FTD induced pluripotent stem cell derived neurons.

Rothstein JD, Baskerville V, Rapuri S, Mehlhop E, Jafar-Nejad P, Rigo F, Bennett F, Mizielinska S, Isaacs A, Coyne AN. Rothstein JD, et al. Among authors: bennett f. Acta Neuropathol. 2023 Nov 29;147(1):1. doi: 10.1007/s00401-023-02652-3. Acta Neuropathol. 2023. PMID: 38019311 Free PMC article.

2

Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS.

Coyne AN, Baskerville V, Zaepfel BL, Dickson DW, Rigo F, Bennett F, Lusk CP, Rothstein JD. Coyne AN, et al. Among authors: bennett f. Sci Transl Med. 2021 Jul 28;13(604):eabe1923. doi: 10.1126/scitranslmed.abe1923. Sci Transl Med. 2021. PMID: 34321318 Free PMC article.

3

Enhanced Delivery of Ligand-Conjugated Antisense Oligonucleotides (C16-HA-ASO) Targeting Dystrophia Myotonica Protein Kinase Transcripts for the Treatment of Myotonic Dystrophy Type 1.

Ait Benichou S, Jauvin D, De Serres-Bérard T, Bennett F, Rigo F, Gourdon G, Boutjdir M, Chahine M, Puymirat J. Ait Benichou S, et al. Among authors: bennett f. Hum Gene Ther. 2022 Aug;33(15-16):810-820. doi: 10.1089/hum.2022.069. Hum Gene Ther. 2022. PMID: 35794764

4

An endogenous peptide marker differentiates SOD1 stability and facilitates pharmacodynamic monitoring in SOD1 amyotrophic lateral sclerosis.

Gertsman I, Wuu J, McAlonis-Downes M, Ghassemian M, Ling K, Rigo F, Bennett F, Benatar M, Miller TM, Da Cruz S. Gertsman I, et al. Among authors: bennett f. JCI Insight. 2019 May 16;4(10):e122768. doi: 10.1172/jci.insight.122768. eCollection 2019 May 16. JCI Insight. 2019. PMID: 31092730 Free PMC article.

5

Effect of dose and plasma concentration on liver uptake and pharmacologic activity of a 2'-methoxyethyl modified chimeric antisense oligonucleotide targeting PTEN.

Geary RS, Wancewicz E, Matson J, Pearce M, Siwkowski A, Swayze E, Bennett F. Geary RS, et al. Among authors: bennett f. Biochem Pharmacol. 2009 Aug 1;78(3):284-91. doi: 10.1016/j.bcp.2009.04.013. Epub 2009 Apr 22. Biochem Pharmacol. 2009. PMID: 19393225

6

Pharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout Mice.

Shemesh CS, Yu RZ, Gaus HJ, Seth PP, Swayze EE, Bennett FC, Geary RS, Henry SP, Wang Y. Shemesh CS, et al. Nucleic Acid Ther. 2016 Aug;26(4):223-35. doi: 10.1089/nat.2016.0607. Epub 2016 Mar 31. Nucleic Acid Ther. 2016. PMID: 27031383

7

Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice.

Nazor Friberg K, Hung G, Wancewicz E, Giles K, Black C, Freier S, Bennett F, Dearmond SJ, Freyman Y, Lessard P, Ghaemmaghami S, Prusiner SB. Nazor Friberg K, et al. Among authors: bennett f. Mol Ther Nucleic Acids. 2012 Feb 7;1(2):e9. doi: 10.1038/mtna.2011.6. Mol Ther Nucleic Acids. 2012. PMID: 23344724 Free PMC article.

8

Toxicological and pharmacokinetic properties of chemically modified antisense oligonucleotide inhibitors of PKC-alpha and C-raf kinase.

Henry SP, Monteith D, Bennett F, Levin AA. Henry SP, et al. Among authors: bennett f. Anticancer Drug Des. 1997 Jul;12(5):409-20. Anticancer Drug Des. 1997. PMID: 9236856 Review. No abstract available.

9

Microglia cannibalism during neurodevelopment results in necroptotic cell death.

Bennett FC, Bennett ML. Bennett FC, et al. PLoS Biol. 2024 Oct 31;22(10):e3002869. doi: 10.1371/journal.pbio.3002869. eCollection 2024 Oct. PLoS Biol. 2024. PMID: 39480876 Free PMC article.

10

ASO Visual Abstract: Racial Disparities in Liver Transplant for Hepatitis C-Associated Hepatocellular Carcinoma.

Bennett FJ, Keilson JM, Turgeon MK, Oppat KM, Warren EAK, Shah SA, Agopian VG, Magliocca JF, Cameron A, Orloff SL, Kubal CA, Cannon RM, Akoad ME, Emamaullee J, Aucejo F, Vagefi PA, Nguyen MH, Dhanireddy K, Kazimi MM, Sonnenday CJ, Foley DP, Abdouljoud M, Sudan DL, Humar A, Doyle MBM, Chapman WC, Maithel SK. Bennett FJ, et al. Ann Surg Oncol. 2024 Oct 29. doi: 10.1245/s10434-024-16410-6. Online ahead of print. Ann Surg Oncol. 2024. PMID: 39470892 No abstract available.

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