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A phase I oncolytic virus trial with vesicular stomatitis virus expressing human interferon beta and tyrosinase related protein 1 administered intratumorally and intravenously in uveal melanoma: safety, efficacy, and T cell responses.
Smith KER, Peng KW, Pulido JS, Weisbrod AJ, Strand CA, Allred JB, Newsom AN, Zhang L, Packiriswamy N, Kottke T, Tonne JM, Moore M, Montane HN, Kottschade LA, McWilliams RR, Dudek AZ, Yan Y, Dimou A, Markovic SN, Federspiel MJ, Vile RG, Dronca RS, Block MS. Smith KER, et al. Among authors: vile rg. Front Immunol. 2023 Oct 31;14:1279387. doi: 10.3389/fimmu.2023.1279387. eCollection 2023. Front Immunol. 2023. PMID: 38022659 Free PMC article. Clinical Trial.
Route of self-amplifying mRNA vaccination modulates the establishment of pulmonary resident memory CD8 and CD4 T cells.
Künzli M, O'Flanagan SD, LaRue M, Talukder P, Dileepan T, Stolley JM, Soerens AG, Quarnstrom CF, Wijeyesinghe S, Ye Y, McPartlan JS, Mitchell JS, Mandl CW, Vile R, Jenkins MK, Ahmed R, Vezys V, Chahal JS, Masopust D. Künzli M, et al. Sci Immunol. 2022 Dec 9;7(78):eadd3075. doi: 10.1126/sciimmunol.add3075. Epub 2022 Dec 2. Sci Immunol. 2022. PMID: 36459542 Free PMC article.
Oncolytic viruses: Narcissistic or altruistic arsonists?
Kendall L, Vile RG. Kendall L, et al. Among authors: vile rg. Mol Ther Oncolytics. 2023 Apr 26;29:42-43. doi: 10.1016/j.omto.2023.04.002. eCollection 2023 Jun 15. Mol Ther Oncolytics. 2023. PMID: 37168933 Free PMC article. No abstract available.
Anti-PD-1 and Extended Half-life IL2 Synergize for Treatment of Murine Glioblastoma Independent of Host MHC Class I Expression.
Tritz ZP, Ayasoufi K, Wolf DM, Owens CA, Malo CS, Himes BT, Fain CE, Goddery EN, Yokanovich LT, Jin F, Hansen MJ, Parney IF, Wang C, Moynihan KD, Irvine DJ, Wittrup KD, Diaz Marcano RM, Vile RG, Johnson AJ. Tritz ZP, et al. Among authors: vile rg. Cancer Immunol Res. 2023 Jun 2;11(6):763-776. doi: 10.1158/2326-6066.CIR-22-0570. Cancer Immunol Res. 2023. PMID: 36921098 Free PMC article.
192 results