Venkatakrishnan K - Search Results

1

Model-based meta-analysis using latent variable modeling to set benchmarks for new treatments of systemic lupus erythematosus.

Goteti K, Garcia R, Gillespie WR, French J, Klopp-Schulze L, Li Y, Mateo CV, Roy S, Guenther O, Benincosa L, Venkatakrishnan K. Goteti K, et al. Among authors: venkatakrishnan k. CPT Pharmacometrics Syst Pharmacol. 2024 Feb;13(2):281-295. doi: 10.1002/psp4.13083. Epub 2023 Dec 4. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38050332 Free PMC article.

2

Identification of glycine-extended CCK peptides in endocrine cells and modulation of CCK amide and CCK Gly content and secretion from endocrine tumor cells by an inhibitor of amidation.

Beinfeld MC, Perloff MD, Venkatakrishnan K. Beinfeld MC, et al. Among authors: venkatakrishnan k. Peptides. 1998;19(8):1393-8. doi: 10.1016/s0196-9781(98)00098-9. Peptides. 1998. PMID: 9809654

3

The utility of in vitro cytochrome P450 inhibition data in the prediction of drug-drug interactions.

Obach RS, Walsky RL, Venkatakrishnan K, Gaman EA, Houston JB, Tremaine LM. Obach RS, et al. Among authors: venkatakrishnan k. J Pharmacol Exp Ther. 2006 Jan;316(1):336-48. doi: 10.1124/jpet.105.093229. Epub 2005 Sep 28. J Pharmacol Exp Ther. 2006. PMID: 16192315

4

Mechanism-based inactivation of human cytochrome p450 enzymes and the prediction of drug-drug interactions.

Obach RS, Walsky RL, Venkatakrishnan K. Obach RS, et al. Among authors: venkatakrishnan k. Drug Metab Dispos. 2007 Feb;35(2):246-55. doi: 10.1124/dmd.106.012633. Epub 2006 Nov 8. Drug Metab Dispos. 2007. PMID: 17093004

5

Pharmacokinetics and safety of bortezomib in patients with advanced malignancies and varying degrees of liver dysfunction: phase I NCI Organ Dysfunction Working Group Study NCI-6432.

LoRusso PM, Venkatakrishnan K, Ramanathan RK, Sarantopoulos J, Mulkerin D, Shibata SI, Hamilton A, Dowlati A, Mani S, Rudek MA, Takimoto CH, Neuwirth R, Esseltine DL, Ivy P. LoRusso PM, et al. Among authors: venkatakrishnan k. Clin Cancer Res. 2012 May 15;18(10):2954-63. doi: 10.1158/1078-0432.CCR-11-2873. Epub 2012 Mar 6. Clin Cancer Res. 2012. PMID: 22394984 Free PMC article. Clinical Trial.

6

Mechanism of cytochrome P450-3A inhibition by ketoconazole.

Greenblatt DJ, Zhao Y, Venkatakrishnan K, Duan SX, Harmatz JS, Parent SJ, Court MH, von Moltke LL. Greenblatt DJ, et al. Among authors: venkatakrishnan k. J Pharm Pharmacol. 2011 Feb;63(2):214-21. doi: 10.1111/j.2042-7158.2010.01202.x. J Pharm Pharmacol. 2011. PMID: 21235585

7

Kinetics and dynamics of intravenous adinazolam, N-desmethyl adinazolam, and alprazolam in healthy volunteers.

Venkatakrishnan K, Culm KE, Ehrenberg BL, Harmatz JS, Corbett KE, Fleishaker JC, Greenblatt DJ. Venkatakrishnan K, et al. J Clin Pharmacol. 2005 May;45(5):529-37. doi: 10.1177/0091270004269105. J Clin Pharmacol. 2005. PMID: 15831776 Clinical Trial.

8

Five distinct human cytochromes mediate amitriptyline N-demethylation in vitro: dominance of CYP 2C19 and 3A4.

Venkatakrishnan K, Greenblatt DJ, von Moltke LL, Schmider J, Harmatz JS, Shader RI. Venkatakrishnan K, et al. J Clin Pharmacol. 1998 Feb;38(2):112-21. doi: 10.1002/j.1552-4604.1998.tb04399.x. J Clin Pharmacol. 1998. PMID: 9549641

9

Mechanism-based inactivation of human cytochrome P450 enzymes: strategies for diagnosis and drug-drug interaction risk assessment.

Venkatakrishnan K, Obach RS, Rostami-Hodjegan A. Venkatakrishnan K, et al. Xenobiotica. 2007 Oct-Nov;37(10-11):1225-56. doi: 10.1080/00498250701670945. Xenobiotica. 2007. PMID: 17968744 Review.

10

Sources of variability in ketoconazole inhibition of human cytochrome P450 3A in vitro.

Greenblatt DJ, Venkatakrishnan K, Harmatz JS, Parent SJ, von Moltke LL. Greenblatt DJ, et al. Among authors: venkatakrishnan k. Xenobiotica. 2010 Oct;40(10):713-20. doi: 10.3109/00498254.2010.506224. Xenobiotica. 2010. PMID: 20712450 Review.

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