Xiao W - Search Results

1

TLR9-independent CD8⁺ T cell responses in hepatic AAV gene transfer through IL-1R1-MyD88 signaling.

Kumar SRP, Biswas M, Cao D, Arisa S, Muñoz-Melero M, Lam AK, Piñeros AR, Kapur R, Kaisho T, Kaufman RJ, Xiao W, Shayakhmetov DM, Terhorst C, de Jong YP, Herzog RW. Kumar SRP, et al. Among authors: xiao w. Mol Ther. 2024 Feb 7;32(2):325-339. doi: 10.1016/j.ymthe.2023.11.029. Epub 2023 Dec 5. Mol Ther. 2024. PMID: 38053332 Free article.

2

Fast and high-throughput LC-MS characterization, and peptide mapping of engineered AAV capsids using LC-MS/MS.

Lam AK, Zhang J, Frabutt D, Mulcrone PL, Li L, Zeng L, Herzog RW, Xiao W. Lam AK, et al. Among authors: xiao w. Mol Ther Methods Clin Dev. 2022 Sep 24;27:185-194. doi: 10.1016/j.omtm.2022.09.008. eCollection 2022 Dec 8. Mol Ther Methods Clin Dev. 2022. PMID: 36284765 Free PMC article.

3

Adding recombinant AAVs to the cancer therapeutics mix.

Mulcrone PL, Herzog RW, Xiao W. Mulcrone PL, et al. Among authors: xiao w. Mol Ther Oncolytics. 2022 Oct 2;27:73-88. doi: 10.1016/j.omto.2022.09.009. eCollection 2022 Dec 15. Mol Ther Oncolytics. 2022. PMID: 36321134 Free PMC article. Review.

4

Cryptic resolution sites in the vector plasmid lead to the heterogeneities in the rAAV vectors.

Zhang J, Chrzanowski M, Frabutt DA, Lam AK, Mulcrone PL, Li L, Konkle BA, Miao CH, Xiao W. Zhang J, et al. Among authors: xiao w. J Med Virol. 2023 Jan;95(1):e28433. doi: 10.1002/jmv.28433. J Med Virol. 2023. PMID: 36571262 Free PMC article.

5

Chemical modification of AAV9 capsid with N-ethyl maleimide alters vector tissue tropism.

Mulcrone PL, Lam AK, Frabutt D, Zhang J, Chrzanowski M, Herzog RW, Xiao W. Mulcrone PL, et al. Among authors: xiao w. Sci Rep. 2023 May 25;13(1):8436. doi: 10.1038/s41598-023-35547-0. Sci Rep. 2023. PMID: 37231038 Free PMC article.

6

Liver-specific in vivo base editing of Angptl3 via AAV delivery efficiently lowers blood lipid levels in mice.

Zuo Y, Zhang C, Zhou Y, Li H, Xiao W, Herzog RW, Xu J, Zhang J, Chen YE, Han R. Zuo Y, et al. Among authors: xiao w. Cell Biosci. 2023 Jun 15;13(1):109. doi: 10.1186/s13578-023-01036-0. Cell Biosci. 2023. PMID: 37322547 Free PMC article.

7

Antibody Binding to Recombinant Adeno Associated Virus Monitored by Charge Detection Mass Spectrometry.

Grande AE, Li X, Miller LM, Zhang J, Draper BE, Herzog RW, Xiao W, Jarrold MF. Grande AE, et al. Among authors: xiao w. Anal Chem. 2023 Jul 25;95(29):10864-10868. doi: 10.1021/acs.analchem.3c02371. Epub 2023 Jul 12. Anal Chem. 2023. PMID: 37436182

8

Quantitative analysis of preferential utilization of AAV ITR as the packaging terminal signal.

Li X, Miller LM, Chrzanowski M, Tian J, Jarrold MF, Herzog RW, Xiao W, Draper B, Zhang J. Li X, et al. Among authors: xiao w. Front Bioeng Biotechnol. 2023 Dec 20;11:1327433. doi: 10.3389/fbioe.2023.1327433. eCollection 2023. Front Bioeng Biotechnol. 2023. PMID: 38173872 Free PMC article.

9

A novel class of self-complementary AAV vectors with multiple advantages based on cceAAV lacking mutant ITR.

Zhang J, Frabutt DA, Chrzanowski M, Li N, Miller LM, Tian J, Mulcrone PL, Lam AK, Draper BE, Jarrold MF, Herzog RW, Xiao W. Zhang J, et al. Among authors: xiao w. Mol Ther Methods Clin Dev. 2024 Feb 3;32(1):101206. doi: 10.1016/j.omtm.2024.101206. eCollection 2024 Mar 14. Mol Ther Methods Clin Dev. 2024. PMID: 38390555 Free PMC article.

10

Thorough molecular configuration analysis of noncanonical AAV genomes in AAV vector preparations.

Zhang J, Yu X, Chrzanowski M, Tian J, Pouchnik D, Guo P, Herzog RW, Xiao W. Zhang J, et al. Among authors: xiao w. Mol Ther Methods Clin Dev. 2024 Feb 19;32(1):101215. doi: 10.1016/j.omtm.2024.101215. eCollection 2024 Mar 14. Mol Ther Methods Clin Dev. 2024. PMID: 38463141 Free PMC article.

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