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A replicating LCMV-based vaccine for the treatment of solid tumors.
Purde MT, Cupovic J, Palmowski YA, Makky A, Schmidt S, Rochwarger A, Hartmann F, Stemeseder F, Lercher A, Abdou MT, Bomze D, Besse L, Berner F, Tüting T, Hölzel M, Bergthaler A, Kochanek S, Ludewig B, Lauterbach H, Orlinger KK, Bald T, Schietinger A, Schürch C, Ring SS, Flatz L. Purde MT, et al. Among authors: kochanek s. Mol Ther. 2024 Feb 7;32(2):426-439. doi: 10.1016/j.ymthe.2023.11.026. Epub 2023 Dec 5. Mol Ther. 2024. PMID: 38058126 Free article.
Heterologous DNA-prime/protein-boost immunization with a monomeric SARS-CoV-2 spike antigen redundantizes the trimeric receptor-binding domain structure to induce neutralizing antibodies in old mice.
Pflumm D, Seidel A, Klein F, Groß R, Krutzke L, Kochanek S, Kroschel J, Münch J, Stifter K, Schirmbeck R. Pflumm D, et al. Among authors: kochanek s. Front Immunol. 2023 Sep 11;14:1231274. doi: 10.3389/fimmu.2023.1231274. eCollection 2023. Front Immunol. 2023. PMID: 37753087 Free PMC article.
General loss of proteostasis links Huntington disease to Cockayne syndrome.
Wagner M, Zhu G, Khalid F, Phan T, Maity P, Lupu L, Agyeman-Duah E, Wiese S, Lindenberg KS, Schön M, Landwehrmeyer GB, Penzo M, Kochanek S, Scharffetter-Kochanek K, Mulaw M, Iben S. Wagner M, et al. Among authors: kochanek s. Neurobiol Dis. 2024 Oct 15;201:106668. doi: 10.1016/j.nbd.2024.106668. Epub 2024 Sep 14. Neurobiol Dis. 2024. PMID: 39284372 Free article.
Discovery and Optimization of First-in-Class Molecular Glue Degraders of the WIZ Transcription Factor for Fetal Hemoglobin Induction to Treat Sickle Cell Disease.
Kerrigan JR, Thomsen NM, Cernijenko A, Kochanek SE, Dewhurst J, O'Brien G, Ware NF, Sanchez CC, Manning JR, Ma X, Ornelas E, Savage NA, Partridge JR, Patterson AW, Lam P, Dales NA, Bonazzi S, Borikar S, Hinman AE, Ting PY. Kerrigan JR, et al. Among authors: kochanek se. J Med Chem. 2024 Nov 28;67(22):20682-20694. doi: 10.1021/acs.jmedchem.4c02251. Epub 2024 Nov 14. J Med Chem. 2024. PMID: 39541509
Understanding thrombosis with thrombocytopenia syndrome after COVID-19 vaccination.
Buoninfante A, Andeweg A, Baker AT, Borad M, Crawford N, Dogné JM, Garcia-Azorin D, Greinacher A, Helfand R, Hviid A, Kochanek S, López-Fauqued M, Nazy I, Padmanabhan A, Pavord S, Prieto-Alhambra D, Tran H, Wandel Liminga U, Cavaleri M. Buoninfante A, et al. Among authors: kochanek s. NPJ Vaccines. 2022 Nov 9;7(1):141. doi: 10.1038/s41541-022-00569-8. NPJ Vaccines. 2022. PMID: 36351906 Free PMC article.
160 results