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Identifying chemogenetic interactions from CRISPR screens with drugZ.
Colic M, Wang G, Zimmermann M, Mascall K, McLaughlin M, Bertolet L, Lenoir WF, Moffat J, Angers S, Durocher D, Hart T. Colic M, et al. Among authors: hart t. Genome Med. 2019 Aug 22;11(1):52. doi: 10.1186/s13073-019-0665-3. Genome Med. 2019. PMID: 31439014 Free PMC article.
Chemogenetic interactions in human cancer cells.
Colic M, Hart T. Colic M, et al. Among authors: hart t. Comput Struct Biotechnol J. 2019 Oct 26;17:1318-1325. doi: 10.1016/j.csbj.2019.09.006. eCollection 2019. Comput Struct Biotechnol J. 2019. PMID: 31921397 Free PMC article. Review.
Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity.
Wertz MH, Mitchem MR, Pineda SS, Hachigian LJ, Lee H, Lau V, Powers A, Kulicke R, Madan GK, Colic M, Therrien M, Vernon A, Beja-Glasser VF, Hegde M, Gao F, Kellis M, Hart T, Doench JG, Heiman M. Wertz MH, et al. Among authors: hart t. Neuron. 2020 Apr 8;106(1):76-89.e8. doi: 10.1016/j.neuron.2020.01.004. Epub 2020 Jan 30. Neuron. 2020. PMID: 32004439 Free PMC article.
AR-negative prostate cancer is vulnerable to loss of JMJD1C demethylase.
Yoshihama Y, LaBella KA, Kim E, Bertolet L, Colic M, Li J, Shang X, Wu CJ, Spring DJ, Wang YA, Hart T, DePinho RA. Yoshihama Y, et al. Among authors: hart t. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2026324118. doi: 10.1073/pnas.2026324118. Proc Natl Acad Sci U S A. 2021. PMID: 34475205 Free PMC article.
Common computational tools for analyzing CRISPR screens.
Colic M, Hart T. Colic M, et al. Among authors: hart t. Emerg Top Life Sci. 2021 Dec 21;5(6):779-788. doi: 10.1042/ETLS20210222. Emerg Top Life Sci. 2021. PMID: 34881774 Free PMC article. Review.
1,061 results