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Page 1
Blockade of the protease ADAM17 ameliorates experimental pancreatitis.
Saad MI, Weng T, Lundy J, Gearing LJ, West AC, Harpur CM, Alanazi M, Hodges C, Croagh D, Kumar B, Sagi I, Rose-John S, Jenkins BJ. Saad MI, et al. Among authors: west ac. Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2213744119. doi: 10.1073/pnas.2213744119. Epub 2022 Oct 10. Proc Natl Acad Sci U S A. 2022. PMID: 36215509 Free PMC article.
Oncogenic dependency on STAT3 serine phosphorylation in KRAS mutant lung cancer.
Alhayyani S, McLeod L, West AC, Balic JJ, Hodges C, Yu L, Smith JA, Prodanovic Z, Bozinovski S, Kumar B, Ruwanpura SM, Saad MI, Jenkins BJ. Alhayyani S, et al. Among authors: west ac. Oncogene. 2022 Feb;41(6):809-823. doi: 10.1038/s41388-021-02134-4. Epub 2021 Dec 3. Oncogene. 2022. PMID: 34857889
Toll-like Receptor 9 Promotes Initiation of Gastric Tumorigenesis by Augmenting Inflammation and Cellular Proliferation.
Tang K, McLeod L, Livis T, West AC, Dawson R, Yu L, Balic JJ, Chonwerawong M, Wray-McCann G, Oshima H, Oshima M, Deswaerte V, Ferrero RL, Jenkins BJ. Tang K, et al. Among authors: west ac. Cell Mol Gastroenterol Hepatol. 2022;14(3):567-586. doi: 10.1016/j.jcmgh.2022.06.002. Epub 2022 Jun 15. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35716851 Free PMC article.
Cross-talk between IL-6 trans-signaling and AIM2 inflammasome/IL-1β axes bridge innate immunity and epithelial apoptosis to promote emphysema.
Ruwanpura SM, McLeod L, Dousha LF, Seow HJ, West AC, West AJ, Weng T, Alanazi M, MacDonald M, King PT, Bardin PG, Gabay C, Klinman DM, Bozinovski S, Vlahos R, Anderson GP, Rose-John S, Saad MI, Jenkins BJ. Ruwanpura SM, et al. Among authors: west aj, west ac. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2201494119. doi: 10.1073/pnas.2201494119. Epub 2022 Aug 29. Proc Natl Acad Sci U S A. 2022. PMID: 36037355 Free PMC article.
STAT3-mediated upregulation of the AIM2 DNA sensor links innate immunity with cell migration to promote epithelial tumourigenesis.
Dawson RE, Deswaerte V, West AC, Tang K, West AJ, Balic JJ, Gearing LJ, Saad MI, Yu L, Wu Y, Bhathal PS, Kumar B, Chakrabarti JT, Zavros Y, Oshima H, Klinman DM, Oshima M, Tan P, Jenkins BJ. Dawson RE, et al. Among authors: west aj, west ac. Gut. 2022 Aug;71(8):1515-1531. doi: 10.1136/gutjnl-2020-323916. Epub 2021 Sep 6. Gut. 2022. PMID: 34489308
95 results