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Page 1
Isolation and detection of DNA-protein crosslinks in mammalian cells.
Torrecilla I, Ruggiano A, Kiianitsa K, Aljarbou F, Lascaux P, Hoslett G, Song W, Maizels N, Ramadan K. Torrecilla I, et al. Nucleic Acids Res. 2024 Jan 25;52(2):525-547. doi: 10.1093/nar/gkad1178. Nucleic Acids Res. 2024. PMID: 38084926 Free PMC article.
Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair.
Vaz B, Popovic M, Newman JA, Fielden J, Aitkenhead H, Halder S, Singh AN, Vendrell I, Fischer R, Torrecilla I, Drobnitzky N, Freire R, Amor DJ, Lockhart PJ, Kessler BM, McKenna GW, Gileadi O, Ramadan K. Vaz B, et al. Among authors: torrecilla i. Mol Cell. 2016 Nov 17;64(4):704-719. doi: 10.1016/j.molcel.2016.09.032. Epub 2016 Oct 27. Mol Cell. 2016. PMID: 27871366 Free PMC article.
SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication.
Halder S, Torrecilla I, Burkhalter MD, Popović M, Fielden J, Vaz B, Oehler J, Pilger D, Lessel D, Wiseman K, Singh AN, Vendrell I, Fischer R, Philipp M, Ramadan K. Halder S, et al. Among authors: torrecilla i. Nat Commun. 2019 Jul 17;10(1):3142. doi: 10.1038/s41467-019-11095-y. Nat Commun. 2019. PMID: 31316063 Free PMC article.
The p97-Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8.
Singh AN, Oehler J, Torrecilla I, Kilgas S, Li S, Vaz B, Guérillon C, Fielden J, Hernandez-Carralero E, Cabrera E, Tullis ID, Meerang M, Barber PR, Freire R, Parsons J, Vojnovic B, Kiltie AE, Mailand N, Ramadan K. Singh AN, et al. Among authors: torrecilla i. EMBO J. 2019 Oct 4;38(21):e102361. doi: 10.15252/embj.2019102361. Epub 2019 Oct 15. EMBO J. 2019. PMID: 31613024 Free PMC article.
TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts.
Fielden J, Wiseman K, Torrecilla I, Li S, Hume S, Chiang SC, Ruggiano A, Narayan Singh A, Freire R, Hassanieh S, Domingo E, Vendrell I, Fischer R, Kessler BM, Maughan TS, El-Khamisy SF, Ramadan K. Fielden J, et al. Among authors: torrecilla i. Nat Commun. 2020 Mar 9;11(1):1274. doi: 10.1038/s41467-020-15000-w. Nat Commun. 2020. PMID: 32152270 Free PMC article.
TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival.
Lascaux P, Hoslett G, Tribble S, Trugenberger C, Antičević I, Otten C, Torrecilla I, Koukouravas S, Zhao Y, Yang H, Aljarbou F, Ruggiano A, Song W, Peron C, Deangeli G, Domingo E, Bancroft J, Carrique L, Johnson E, Vendrell I, Fischer R, Ng AWT, Ngeow J, D'Angiolella V, Raimundo N, Maughan T, Popović M, Milošević I, Ramadan K. Lascaux P, et al. Among authors: torrecilla i. Cell. 2024 Oct 3;187(20):5698-5718.e26. doi: 10.1016/j.cell.2024.08.020. Epub 2024 Sep 11. Cell. 2024. PMID: 39265577 Free article.
Toward an integrated multi-gigahertz ionizing particle diagnostic.
Bohon J, Grace C, Gulley M, Jacobson B, Kachiguine S, Kim D, Martinez-Mckinney F, Nagel N, Nizam M, Padilla R, Prakash T, Prebys E, Rowling C, Schumm BA, Torrecilla IS, Smedley J, Stuart D, Wilder M, Zhu D. Bohon J, et al. Among authors: torrecilla is. Rev Sci Instrum. 2024 Jun 1;95(6):063507. doi: 10.1063/5.0213921. Rev Sci Instrum. 2024. PMID: 38934713
22 results