Czabotar PE - Search Results

1

Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids.

Miller MS, Cowan AD, Brouwer JM, Smyth ST, Peng L, Wardak AZ, Uren RT, Luo C, Roy MJ, Shah S, Tan Z, Reid GE, Colman PM, Czabotar PE. Miller MS, et al. Among authors: czabotar pe. FEBS J. 2024 Jun;291(11):2335-2353. doi: 10.1111/febs.17031. Epub 2024 Jan 19. FEBS J. 2024. PMID: 38088212

2

Studies of structural changes in the M2 proton channel of influenza A virus by tryptophan fluorescence.

Czabotar PE, Martin SR, Hay AJ. Czabotar PE, et al. Virus Res. 2004 Jan;99(1):57-61. doi: 10.1016/j.virusres.2003.10.004. Virus Res. 2004. PMID: 14687947

3

Structural insights into the degradation of Mcl-1 induced by BH3 domains.

Czabotar PE, Lee EF, van Delft MF, Day CL, Smith BJ, Huang DC, Fairlie WD, Hinds MG, Colman PM. Czabotar PE, et al. Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6217-22. doi: 10.1073/pnas.0701297104. Epub 2007 Mar 27. Proc Natl Acad Sci U S A. 2007. PMID: 17389404 Free PMC article.

4

A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation.

Lee EF, Czabotar PE, van Delft MF, Michalak EM, Boyle MJ, Willis SN, Puthalakath H, Bouillet P, Colman PM, Huang DC, Fairlie WD. Lee EF, et al. Among authors: czabotar pe. J Cell Biol. 2008 Jan 28;180(2):341-55. doi: 10.1083/jcb.200708096. Epub 2008 Jan 21. J Cell Biol. 2008. PMID: 18209102 Free PMC article.

5

Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands.

Kvansakul M, Yang H, Fairlie WD, Czabotar PE, Fischer SF, Perugini MA, Huang DC, Colman PM. Kvansakul M, et al. Among authors: czabotar pe. Cell Death Differ. 2008 Oct;15(10):1564-71. doi: 10.1038/cdd.2008.83. Epub 2008 Jun 13. Cell Death Differ. 2008. PMID: 18551131

6

BCL-2 family antagonists for cancer therapy.

Lessene G, Czabotar PE, Colman PM. Lessene G, et al. Among authors: czabotar pe. Nat Rev Drug Discov. 2008 Dec;7(12):989-1000. doi: 10.1038/nrd2658. Nat Rev Drug Discov. 2008. PMID: 19043450 Review.

7

High-resolution structural characterization of a helical alpha/beta-peptide foldamer bound to the anti-apoptotic protein Bcl-xL.

Lee EF, Sadowsky JD, Smith BJ, Czabotar PE, Peterson-Kaufman KJ, Colman PM, Gellman SH, Fairlie WD. Lee EF, et al. Among authors: czabotar pe. Angew Chem Int Ed Engl. 2009;48(24):4318-22. doi: 10.1002/anie.200805761. Angew Chem Int Ed Engl. 2009. PMID: 19229915 Free PMC article.

8

Bax activation by Bim?

Czabotar PE, Colman PM, Huang DC. Czabotar PE, et al. Cell Death Differ. 2009 Sep;16(9):1187-91. doi: 10.1038/cdd.2009.83. Epub 2009 Jun 26. Cell Death Differ. 2009. PMID: 19557009 Review.

9

Conformational changes in Bcl-2 pro-survival proteins determine their capacity to bind ligands.

Lee EF, Czabotar PE, Yang H, Sleebs BE, Lessene G, Colman PM, Smith BJ, Fairlie WD. Lee EF, et al. Among authors: czabotar pe. J Biol Chem. 2009 Oct 30;284(44):30508-17. doi: 10.1074/jbc.M109.040725. Epub 2009 Sep 2. J Biol Chem. 2009. PMID: 19726685 Free PMC article.

10

Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes.

Xu Y, Kershaw NJ, Luo CS, Soo P, Pocock MJ, Czabotar PE, Hilton DJ, Nicola NA, Garrett TP, Zhang JG. Xu Y, et al. Among authors: czabotar pe. J Biol Chem. 2010 Jul 9;285(28):21214-8. doi: 10.1074/jbc.C110.129502. Epub 2010 May 20. J Biol Chem. 2010. PMID: 20489211 Free PMC article.

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