Lemieux GA - Search Results

1

The steroid hormone ADIOL promotes learning by reducing neural kynurenic acid levels.

Lemieux GA, Yoo S, Lin L, Vohra M, Ashrafi K. Lemieux GA, et al. Genes Dev. 2023 Dec 26;37(21-24):998-1016. doi: 10.1101/gad.350745.123. Genes Dev. 2023. PMID: 38092521 Free PMC article.

2

Kynurenic acid accumulation underlies learning and memory impairment associated with aging.

Vohra M, Lemieux GA, Lin L, Ashrafi K. Vohra M, et al. Among authors: lemieux ga. Genes Dev. 2018 Jan 1;32(1):14-19. doi: 10.1101/gad.307918.117. Epub 2018 Jan 31. Genes Dev. 2018. PMID: 29386332 Free PMC article.

3

Neural production of kynurenic acid in Caenorhabditis elegans requires the AAT-1 transporter.

Lin L, Lemieux GA, Enogieru OJ, Giacomini KM, Ashrafi K. Lin L, et al. Among authors: lemieux ga. Genes Dev. 2020 Aug 1;34(15-16):1033-1038. doi: 10.1101/gad.339119.120. Epub 2020 Jul 16. Genes Dev. 2020. PMID: 32675325 Free PMC article.

4

Insights and challenges in using C. elegans for investigation of fat metabolism.

Lemieux GA, Ashrafi K. Lemieux GA, et al. Crit Rev Biochem Mol Biol. 2015 Jan-Feb;50(1):69-84. doi: 10.3109/10409238.2014.959890. Epub 2014 Sep 17. Crit Rev Biochem Mol Biol. 2015. PMID: 25228063 Review.

5

Kynurenic acid is a nutritional cue that enables behavioral plasticity.

Lemieux GA, Cunningham KA, Lin L, Mayer F, Werb Z, Ashrafi K. Lemieux GA, et al. Cell. 2015 Jan 15;160(1-2):119-31. doi: 10.1016/j.cell.2014.12.028. Cell. 2015. PMID: 25594177 Free PMC article.

6

Neural Regulatory Pathways of Feeding and Fat in Caenorhabditis elegans.

Lemieux GA, Ashrafi K. Lemieux GA, et al. Annu Rev Genet. 2015;49:413-38. doi: 10.1146/annurev-genet-120213-092244. Epub 2015 Oct 14. Annu Rev Genet. 2015. PMID: 26473379 Review.

7

Investigating Connections between Metabolism, Longevity, and Behavior in Caenorhabditis elegans.

Lemieux GA, Ashrafi K. Lemieux GA, et al. Trends Endocrinol Metab. 2016 Aug;27(8):586-596. doi: 10.1016/j.tem.2016.05.004. Epub 2016 Jun 9. Trends Endocrinol Metab. 2016. PMID: 27289335 Free PMC article. Review.

8

The beneficial effects of dietary restriction on learning are distinct from its effects on longevity and mediated by depletion of a neuroinhibitory metabolite.

Vohra M, Lemieux GA, Lin L, Ashrafi K. Vohra M, et al. Among authors: lemieux ga. PLoS Biol. 2017 Aug 1;15(8):e2002032. doi: 10.1371/journal.pbio.2002032. eCollection 2017 Aug. PLoS Biol. 2017. PMID: 28763436 Free PMC article.

9

Stressing about misplaced fat is a key to longevity.

Lemieux GA, Ashrafi K. Lemieux GA, et al. Elife. 2015 Aug 19;4:e10161. doi: 10.7554/eLife.10161. Elife. 2015. PMID: 26287524 Free PMC article.

10

A whole-organism screen identifies new regulators of fat storage.

Lemieux GA, Liu J, Mayer N, Bainton RJ, Ashrafi K, Werb Z. Lemieux GA, et al. Nat Chem Biol. 2011 Apr;7(4):206-13. doi: 10.1038/nchembio.534. Epub 2011 Mar 13. Nat Chem Biol. 2011. PMID: 21390037 Free PMC article.

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