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Page 1
Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism.
Bilanges B, Alliouachene S, Pearce W, Morelli D, Szabadkai G, Chung YL, Chicanne G, Valet C, Hill JM, Voshol PJ, Collinson L, Peddie C, Ali K, Ghazaly E, Rajeeve V, Trichas G, Srinivas S, Chaussade C, Salamon RS, Backer JM, Scudamore CL, Whitehead MA, Keaney EP, Murphy LO, Semple RK, Payrastre B, Tooze SA, Vanhaesebroeck B. Bilanges B, et al. Among authors: tooze sa. Nat Commun. 2017 Nov 27;8(1):1804. doi: 10.1038/s41467-017-01969-4. Nat Commun. 2017. PMID: 29180704 Free PMC article.
Path to autophagy therapeutics with Beth Levine.
Tooze SA. Tooze SA. Nat Rev Mol Cell Biol. 2020 Oct;21(10):564-565. doi: 10.1038/s41580-020-00282-1. Nat Rev Mol Cell Biol. 2020. PMID: 32770126 No abstract available.
Protein trafficking into autophagosomes.
Young A, Tooze S. Young A, et al. Methods Mol Biol. 2008;445:147-57. doi: 10.1007/978-1-59745-157-4_10. Methods Mol Biol. 2008. PMID: 18425449
Pathogenic Parkinson's disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation.
Manzoni C, Mamais A, Dihanich S, McGoldrick P, Devine MJ, Zerle J, Kara E, Taanman JW, Healy DG, Marti-Masso JF, Schapira AH, Plun-Favreau H, Tooze S, Hardy J, Bandopadhyay R, Lewis PA. Manzoni C, et al. Biochem Biophys Res Commun. 2013 Nov 29;441(4):862-6. doi: 10.1016/j.bbrc.2013.10.159. Epub 2013 Nov 6. Biochem Biophys Res Commun. 2013. PMID: 24211199 Free PMC article.
Autophagy pathway: Cellular and molecular mechanisms.
Yu L, Chen Y, Tooze SA. Yu L, et al. Among authors: tooze sa. Autophagy. 2018;14(2):207-215. doi: 10.1080/15548627.2017.1378838. Epub 2017 Dec 31. Autophagy. 2018. PMID: 28933638 Free PMC article. Review.
Homozygous missense WIPI2 variants cause a congenital disorder of autophagy with neurodevelopmental impairments of variable clinical severity and disease course.
Maroofian R, Gubas A, Kaiyrzhanov R, Scala M, Hundallah K, Severino M, Abdel-Hamid MS, Rosenfeld JA, Ebrahimi-Fakhari D, Ali Z, Rahim F, Houlden H, Tooze SA, Alsaleh NS, Zaki MS. Maroofian R, et al. Among authors: tooze sa. Brain Commun. 2021 Sep 3;3(3):fcab183. doi: 10.1093/braincomms/fcab183. eCollection 2021. Brain Commun. 2021. PMID: 34557665 Free PMC article.
Imaging ATG9A, a Multi-Spanning Membrane Protein.
van Vliet AR, De Tito S, Almacellas E, Tooze SA. van Vliet AR, et al. Among authors: tooze sa. J Vis Exp. 2023 Jun 16;(196). doi: 10.3791/65349. J Vis Exp. 2023. PMID: 37395569
195 results