Li Y - Search Results

1

The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition.

Kimani SW, Perveen S, Szewezyk M, Zeng H, Dong A, Li F, Ghiabi P, Li Y, Chau I, Arrowsmith CH, Barsyte-Lovejoy D, Santhakumar V, Vedadi M, Halabelian L. Kimani SW, et al. Among authors: li f, li y. Commun Biol. 2023 Dec 16;6(1):1272. doi: 10.1038/s42003-023-05655-8. Commun Biol. 2023. PMID: 38104184 Free PMC article.

2

Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1.

Avvakumov GV, Walker JR, Xue S, Li Y, Duan S, Bronner C, Arrowsmith CH, Dhe-Paganon S. Avvakumov GV, et al. Among authors: li y. Nature. 2008 Oct 9;455(7214):822-5. doi: 10.1038/nature07273. Epub 2008 Sep 3. Nature. 2008. PMID: 18772889

3

Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2.

Wu H, Siarheyeva A, Zeng H, Lam R, Dong A, Wu XH, Li Y, Schapira M, Vedadi M, Min J. Wu H, et al. Among authors: li y. FEBS Lett. 2013 Nov 29;587(23):3859-68. doi: 10.1016/j.febslet.2013.10.020. FEBS Lett. 2013. PMID: 24396869 Free article.

4

A Basic Post-SET Extension of NSDs Is Essential for Nucleosome Binding In Vitro.

Allali-Hassani A, Kuznetsova E, Hajian T, Wu H, Dombrovski L, Li Y, Gräslund S, Arrowsmith CH, Schapira M, Vedadi M. Allali-Hassani A, et al. Among authors: li y. J Biomol Screen. 2014 Jul;19(6):928-35. doi: 10.1177/1087057114525854. Epub 2014 Mar 4. J Biomol Screen. 2014. PMID: 24595546

5

Generation and Validation of Intracellular Ubiquitin Variant Inhibitors for USP7 and USP10.

Zhang W, Sartori MA, Makhnevych T, Federowicz KE, Dong X, Liu L, Nim S, Dong A, Yang J, Li Y, Haddad D, Ernst A, Heerding D, Tong Y, Moffat J, Sidhu SS. Zhang W, et al. Among authors: li y. J Mol Biol. 2017 Nov 10;429(22):3546-3560. doi: 10.1016/j.jmb.2017.05.025. Epub 2017 Jun 3. J Mol Biol. 2017. PMID: 28587923

6

Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4.

Liu Y, Qin S, Chen TY, Lei M, Dhar SS, Ho JC, Dong A, Loppnau P, Li Y, Lee MG, Min J. Liu Y, et al. Among authors: li y. Nat Commun. 2019 Jan 3;10(1):36. doi: 10.1038/s41467-018-07906-3. Nat Commun. 2019. PMID: 30604749 Free PMC article.

7

Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X.

Paudel P, Zhang Q, Leung C, Greenberg HC, Guo Y, Chern YH, Dong A, Li Y, Vedadi M, Zhuang Z, Tong Y. Paudel P, et al. Among authors: li y. Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7288-7297. doi: 10.1073/pnas.1815027116. Epub 2019 Mar 26. Proc Natl Acad Sci U S A. 2019. PMID: 30914461 Free PMC article.

8

Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition.

Halabelian L, Ravichandran M, Li Y, Zeng H, Rao A, Aravind L, Arrowsmith CH. Halabelian L, et al. Among authors: li y. Nat Struct Mol Biol. 2019 Jul;26(7):607-612. doi: 10.1038/s41594-019-0246-6. Epub 2019 Jun 24. Nat Struct Mol Biol. 2019. PMID: 31235913 Free PMC article.

9

Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19.

Dong C, Nakagawa R, Oyama K, Yamamoto Y, Zhang W, Dong A, Li Y, Yoshimura Y, Kamiya H, Nakayama JI, Ueda J, Min J. Dong C, et al. Among authors: li y. Elife. 2020 Sep 1;9:e58675. doi: 10.7554/eLife.58675. Elife. 2020. PMID: 32869745 Free PMC article.

10

Crystal structure of the BRPF2 PWWP domain in complex with DNA reveals a different binding mode than the HDGF family of PWWP domains.

Zhang M, Lei M, Qin S, Dong A, Yang A, Li Y, Loppnau P, Hughes TR, Min J, Liu Y. Zhang M, et al. Among authors: li y. Biochim Biophys Acta Gene Regul Mech. 2021 Mar;1864(3):194688. doi: 10.1016/j.bbagrm.2021.194688. Epub 2021 Feb 6. Biochim Biophys Acta Gene Regul Mech. 2021. PMID: 33556623

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