Cao J - Search Results

1

Modifications to 1-(4-(2-Bis(4-fluorophenyl)methyl)sulfinyl)alkyl Alicyclic Amines That Improve Metabolic Stability and Retain an Atypical DAT Inhibitor Profile.

Okorom AV, Camacho-Hernandez GA, Salomon K, Lee KH, Ku TC, Cao J, Won SJ, Friedman J, Lam J, Paule J, Rais R, Klein B, Xi ZX, Shi L, Loland CJ, Newman AH. Okorom AV, et al. Among authors: cao j. J Med Chem. 2024 Jan 11;67(1):709-727. doi: 10.1021/acs.jmedchem.3c02037. Epub 2023 Dec 20. J Med Chem. 2024. PMID: 38117239

2

N-(4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl, butenyl and butynyl)arylcarboxamides as novel dopamine D(3) receptor antagonists.

Newman AH, Cao J, Bennett CJ, Robarge MJ, Freeman RA, Luedtke RR. Newman AH, et al. Among authors: cao j. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2179-83. doi: 10.1016/s0960-894x(03)00389-5. Bioorg Med Chem Lett. 2003. PMID: 12798330

3

Dual probes for the dopamine transporter and sigma1 receptors: novel piperazinyl alkyl-bis(4'-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents.

Cao J, Kulkarni SS, Husbands SM, Bowen WD, Williams W, Kopajtic T, Katz JL, George C, Newman AH. Cao J, et al. J Med Chem. 2003 Jun 19;46(13):2589-98. doi: 10.1021/jm030008u. J Med Chem. 2003. PMID: 12801223

4

Evaluation of the blood-brain barrier transport, population pharmacokinetics, and brain distribution of benztropine analogs and cocaine using in vitro and in vivo techniques.

Raje S, Cao J, Newman AH, Gao H, Eddington ND. Raje S, et al. Among authors: cao j. J Pharmacol Exp Ther. 2003 Nov;307(2):801-8. doi: 10.1124/jpet.103.053504. Epub 2003 Sep 9. J Pharmacol Exp Ther. 2003. PMID: 12966155

5

Novel azido and isothiocyanato analogues of [3-(4-phenylalkylpiperazin-1-yl)propyl]bis(4-fluorophenyl)amines as potential irreversible ligands for the dopamine transporter.

Cao J, Lever JR, Kopajtic T, Katz JL, Pham AT, Holmes ML, Justice JB, Newman AH. Cao J, et al. J Med Chem. 2004 Dec 2;47(25):6128-36. doi: 10.1021/jm049670w. J Med Chem. 2004. PMID: 15566284

6

Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor.

Grundt P, Carlson EE, Cao J, Bennett CJ, McElveen E, Taylor M, Luedtke RR, Newman AH. Grundt P, et al. Among authors: cao j. J Med Chem. 2005 Feb 10;48(3):839-48. doi: 10.1021/jm049465g. J Med Chem. 2005. PMID: 15689168

7

Pharmacodynamic assessment of the benztropine analogues AHN-1055 and AHN-2005 using intracerebral microdialysis to evaluate brain dopamine levels and pharmacokinetic/pharmacodynamic modeling.

Raje S, Cornish J, Newman AH, Cao J, Katz JL, Eddington ND. Raje S, et al. Among authors: cao j. Pharm Res. 2005 Apr;22(4):603-12. doi: 10.1007/s11095-005-2488-8. Epub 2005 Apr 7. Pharm Res. 2005. PMID: 15846468

8

Investigation of the potential pharmacokinetic and pharmaco-dynamic drug interaction between AHN 1-055, a potent benztropine analog used for cocaine abuse, and cocaine after dosing in rats using intracerebral microdialysis.

Raje S, Cornish J, Newman AH, Cao J, Katz JL, Eddington ND. Raje S, et al. Among authors: cao j. Biopharm Drug Dispos. 2006 Jul;27(5):229-40. doi: 10.1002/bdd.497. Biopharm Drug Dispos. 2006. PMID: 16586462

9

Structure-activity relationship studies on a novel series of (S)-2beta-substituted 3alpha-[bis(4-fluoro- or 4-chlorophenyl)methoxy]tropane analogues for in vivo investigation.

Zou MF, Cao J, Kopajtic T, Desai RI, Katz JL, Newman AH. Zou MF, et al. Among authors: cao j. J Med Chem. 2006 Oct 19;49(21):6391-9. doi: 10.1021/jm060762q. J Med Chem. 2006. PMID: 17034144

10

Design and synthesis of a novel photoaffinity ligand for the dopamine and serotonin transporters based on 2beta-carbomethoxy-3beta-biphenyltropane.

Newman AH, Cha JH, Cao J, Kopajtic T, Katz JL, Parnas ML, Vaughan R, Lever JR. Newman AH, et al. Among authors: cao j. J Med Chem. 2006 Nov 2;49(22):6621-5. doi: 10.1021/jm0603973. J Med Chem. 2006. PMID: 17064081

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