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The novel SMYD3 inhibitor EM127 impairs DNA repair response to chemotherapy-induced DNA damage and reverses cancer chemoresistance.
Sanese P, De Marco K, Lepore Signorile M, La Rocca F, Forte G, Latrofa M, Fasano C, Disciglio V, Di Nicola E, Pantaleo A, Bianco G, Spilotro V, Ferroni C, Tubertini M, Labarile N, De Marinis L, Armentano R, Gigante G, Lantone V, Lantone G, Naldi M, Bartolini M, Varchi G, Del Rio A, Grossi V, Simone C. Sanese P, et al. Among authors: lantone v. J Exp Clin Cancer Res. 2024 May 30;43(1):151. doi: 10.1186/s13046-024-03078-9. J Exp Clin Cancer Res. 2024. PMID: 38812026 Free PMC article.