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Page 1
Myeloid cell-derived creatine in the hypoxic niche promotes glioblastoma growth.
Rashidi A, Billingham LK, Zolp A, Chia TY, Silvers C, Katz JL, Park CH, Delay S, Boland L, Geng Y, Markwell SM, Dmello C, Arrieta VA, Zilinger K, Jacob IM, Lopez-Rosas A, Hou D, Castro B, Steffens AM, McCortney K, Walshon JP, Flowers MS, Lin H, Wang H, Zhao J, Sonabend A, Zhang P, Ahmed AU, Brat DJ, Heiland DH, Lee-Chang C, Lesniak MS, Chandel NS, Miska J. Rashidi A, et al. Among authors: lopez rosas a. Cell Metab. 2024 Jan 2;36(1):62-77.e8. doi: 10.1016/j.cmet.2023.11.013. Epub 2023 Dec 21. Cell Metab. 2024. PMID: 38134929
B-cells Drive Response to PD-1 Blockade in Glioblastoma Upon Neutralization of TGFβ-mediated Immunosuppression.
Hou D, Castro B, Dapash M, Zolp A, Katz J, Arrieta V, Biermann J, Melms J, Kueckelhaus J, Benotmane J, Youngblood M, Rashidi A, Billingham L, Dmello C, Vazquez-Cervantes G, Lopez-Rosas A, Han Y, Patel R, Chia TY, Sun L, Prins R, Izar B, Heiland DH, Zhang P, Sonabend A, Miska J, Lesniak M, Zhao J, Lee-Chang C. Hou D, et al. Among authors: lopez rosas a. Res Sq [Preprint]. 2023 Jan 9:rs.3.rs-2399170. doi: 10.21203/rs.3.rs-2399170/v1. Res Sq. 2023. PMID: 36711497 Free PMC article. Preprint.
Antigen-presenting B cells promote TCF-1+ PD1- stem-like CD8+ T-cell proliferation in glioblastoma.
Hou D, Wan H, Katz JL, Wang S, Castro BA, Vazquez-Cervantes GI, Arrieta VA, Dhiantravan S, Najem H, Rashidi A, Chia TY, Arjmandi T, Collado J, Billingham L, Lopez-Rosas A, Han Y, Sonabend AM, Heimberger AB, Zhang P, Miska J, Lee-Chang C. Hou D, et al. Among authors: lopez rosas a. Front Immunol. 2024 Jan 10;14:1295218. doi: 10.3389/fimmu.2023.1295218. eCollection 2023. Front Immunol. 2024. PMID: 38268923 Free PMC article.
STING agonist-loaded, CD47/PD-L1-targeting nanoparticles potentiate antitumor immunity and radiotherapy for glioblastoma.
Zhang P, Rashidi A, Zhao J, Silvers C, Wang H, Castro B, Ellingwood A, Han Y, Lopez-Rosas A, Zannikou M, Dmello C, Levine R, Xiao T, Cordero A, Sonabend AM, Balyasnikova IV, Lee-Chang C, Miska J, Lesniak MS. Zhang P, et al. Among authors: lopez rosas a. Nat Commun. 2023 Mar 23;14(1):1610. doi: 10.1038/s41467-023-37328-9. Nat Commun. 2023. PMID: 36959214 Free PMC article.
HIF-1α Is a Metabolic Switch Between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma.
Miska J, Lee-Chang C, Rashidi A, Muroski ME, Chang AL, Lopez-Rosas A, Zhang P, Panek WK, Cordero A, Han Y, Ahmed AU, Chandel NS, Lesniak MS. Miska J, et al. Among authors: lopez rosas a. Cell Rep. 2022 Jun 7;39(10):110934. doi: 10.1016/j.celrep.2022.110934. Cell Rep. 2022. PMID: 35675772 Free article. No abstract available.
Polyamines drive myeloid cell survival by buffering intracellular pH to promote immunosuppression in glioblastoma.
Miska J, Rashidi A, Lee-Chang C, Gao P, Lopez-Rosas A, Zhang P, Burga R, Castro B, Xiao T, Han Y, Hou D, Sampat S, Cordero A, Stoolman JS, Horbinski CM, Burns M, Reshetnyak YK, Chandel NS, Lesniak MS. Miska J, et al. Among authors: lopez rosas a. Sci Adv. 2021 Feb 17;7(8):eabc8929. doi: 10.1126/sciadv.abc8929. Print 2021 Feb. Sci Adv. 2021. PMID: 33597238 Free PMC article.
Activation of 4-1BBL+ B cells with CD40 agonism and IFNγ elicits potent immunity against glioblastoma.
Lee-Chang C, Miska J, Hou D, Rashidi A, Zhang P, Burga RA, Jusué-Torres I, Xiao T, Arrieta VA, Zhang DY, Lopez-Rosas A, Han Y, Sonabend AM, Horbinski CM, Stupp R, Balyasnikova IV, Lesniak MS. Lee-Chang C, et al. Among authors: lopez rosas a. J Exp Med. 2021 Jan 4;218(1):e20200913. doi: 10.1084/jem.20200913. J Exp Med. 2021. PMID: 32991668 Free PMC article.
GCN2 is essential for CD8+ T cell survival and function in murine models of malignant glioma.
Rashidi A, Miska J, Lee-Chang C, Kanojia D, Panek WK, Lopez-Rosas A, Zhang P, Han Y, Xiao T, Pituch KC, Kim JW, Talebian M, Fares J, Lesniak MS. Rashidi A, et al. Among authors: lopez rosas a. Cancer Immunol Immunother. 2020 Jan;69(1):81-94. doi: 10.1007/s00262-019-02441-6. Epub 2019 Dec 16. Cancer Immunol Immunother. 2020. PMID: 31844909 Free PMC article.
Therapeutic targeting of tumor-associated myeloid cells synergizes with radiation therapy for glioblastoma.
Zhang P, Miska J, Lee-Chang C, Rashidi A, Panek WK, An S, Zannikou M, Lopez-Rosas A, Han Y, Xiao T, Pituch KC, Kanojia D, Balyasnikova IV, Lesniak MS. Zhang P, et al. Among authors: lopez rosas a. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23714-23723. doi: 10.1073/pnas.1906346116. Epub 2019 Nov 11. Proc Natl Acad Sci U S A. 2019. PMID: 31712430 Free PMC article.
Myeloid-Derived Suppressive Cells Promote B cell-Mediated Immunosuppression via Transfer of PD-L1 in Glioblastoma.
Lee-Chang C, Rashidi A, Miska J, Zhang P, Pituch KC, Hou D, Xiao T, Fischietti M, Kang SJ, Appin CL, Horbinski C, Platanias LC, Lopez-Rosas A, Han Y, Balyasnikova IV, Lesniak MS. Lee-Chang C, et al. Among authors: lopez rosas a. Cancer Immunol Res. 2019 Dec;7(12):1928-1943. doi: 10.1158/2326-6066.CIR-19-0240. Epub 2019 Sep 17. Cancer Immunol Res. 2019. PMID: 31530559 Free PMC article.
26 results