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Page 1
Post-translational modifications linked to preclinical Alzheimer's disease-related pathological and cognitive changes.
Abiose O, Rutledge J, Moran-Losada P, Belloy ME, Wilson EN, He Z, Trelle AN, Channappa D, Romero A, Park J, Yutsis MV, Sha SJ, Andreasson KI, Poston KL, Henderson VW, Wagner AD, Wyss-Coray T, Mormino EC. Abiose O, et al. Alzheimers Dement. 2024 Mar;20(3):1851-1867. doi: 10.1002/alz.13576. Epub 2023 Dec 25. Alzheimers Dement. 2024. PMID: 38146099 Free PMC article.
A 3'UTR Insertion Is a Candidate Causal Variant at the TMEM106B Locus Associated with Increased Risk for FTLD-TDP.
Chemparathy A, Guen YL, Zeng Y, Gorzynski J, Jensen T, Yang C, Kasireddy N, Talozzi L, Belloy ME, Stewart I, Gitler AD, Wagner AD, Mormino E, Henderson VW, Wyss-Coray T, Ashley E, Cruchaga C, Greicius MD. Chemparathy A, et al. medRxiv [Preprint]. 2023 Nov 17:2023.07.06.23292312. doi: 10.1101/2023.07.06.23292312. medRxiv. 2023. PMID: 37461476 Free PMC article. Preprint.
Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson's disease.
Rutledge J, Lehallier B, Zarifkar P, Losada PM, Shahid-Besanti M, Western D, Gorijala P, Ryman S, Yutsis M, Deutsch GK, Mormino E, Trelle A, Wagner AD, Kerchner GA, Tian L, Cruchaga C, Henderson VW, Montine TJ, Borghammer P, Wyss-Coray T, Poston KL. Rutledge J, et al. Acta Neuropathol. 2024 Mar 11;147(1):52. doi: 10.1007/s00401-024-02706-0. Acta Neuropathol. 2024. PMID: 38467937 Free PMC article.
A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer's mouse model.
Latif-Hernandez A, Yang T, Butler RR 3rd, Losada PM, Minhas PS, White H, Tran KC, Liu H, Simmons DA, Langness V, Andreasson KI, Wyss-Coray T, Longo FM. Latif-Hernandez A, et al. Among authors: wyss coray t. Alzheimers Dement. 2024 Jul;20(7):4434-4460. doi: 10.1002/alz.13857. Epub 2024 May 23. Alzheimers Dement. 2024. PMID: 38779814 Free PMC article.
Plasma and CSF biomarkers of aging and cognitive decline in Caribbean vervets.
Varma C, Luo E, Bostrom G, Bathini P, Berdnik D, Wyss-Coray T, Zhao T, Dong X, Ervin FR, Beierschmitt A, Palmour RM, Lemere CA. Varma C, et al. Among authors: wyss coray t. Alzheimers Dement. 2024 Aug;20(8):5460-5480. doi: 10.1002/alz.14038. Epub 2024 Jul 1. Alzheimers Dement. 2024. PMID: 38946666 Free PMC article.
Parkinson's disease is characterized by vitamin B6-dependent inflammatory kynurenine pathway dysfunction.
Wilson E, Umans J, Swarovski M, Minhas P, Midttun Ø, Ulvik AA, Shahid-Besanti M, Linortner P, Mhatre S, Wang Q, Channappa D, Corso N, Tian L, Fredericks C, Kerchner G, Plowey E, Cholerton B, Ueland P, Zabetian C, Gray N, Quinn J, Montine T, Sha S, Longo F, Wolk D, Chen-Plotkin A, Henderson V, Wyss-Coray T, Wagner A, Mormino E, Aghaeepour N, Poston K, Andreasson K. Wilson E, et al. Among authors: wyss coray t. Res Sq [Preprint]. 2024 Sep 26:rs.3.rs-4980210. doi: 10.21203/rs.3.rs-4980210/v1. Res Sq. 2024. PMID: 39399688 Free PMC article. Preprint.
A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer's mouse model.
Latif-Hernandez A, Yang T, Raymond-Butler R, Losada PM, Minhas P, White H, Tran KC, Liu H, Simmons DA, Langness V, Andreasson K, Wyss-Coray T, Longo FM. Latif-Hernandez A, et al. bioRxiv [Preprint]. 2023 Sep 18:2023.09.18.558138. doi: 10.1101/2023.09.18.558138. bioRxiv. 2023. Update in: Alzheimers Dement. 2024 Jul;20(7):4434-4460. doi: 10.1002/alz.13857. PMID: 37781573 Free PMC article. Updated. Preprint.
CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease.
Shen Y, Timsina J, Heo G, Beric A, Ali M, Wang C, Yang C, Wang Y, Western D, Liu M, Gorijala P, Budde J, Do A, Liu H, Gordon B, Llibre-Guerra JJ, Joseph-Mathurin N, Perrin RJ, Maschi D, Wyss-Coray T, Pastor P, Renton AE, Surace EI, Johnson ECB, Levey AI, Alvarez I, Levin J, Ringman JM, Allegri RF, Seyfried N, Day GS, Wu Q, Fernández MV, Tarawneh R, McDade E, Morris JC, Bateman RJ, Goate A; Dominantly Inherited Alzheimer Network; Ibanez L, Sung YJ, Cruchaga C. Shen Y, et al. Among authors: wyss coray t. Cell. 2024 Oct 31;187(22):6309-6326.e15. doi: 10.1016/j.cell.2024.08.049. Epub 2024 Sep 26. Cell. 2024. PMID: 39332414 Free PMC article.
Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity.
Lyu YX, Fu Q, Wilczok D, Ying K, King A, Antebi A, Vojta A, Stolzing A, Moskalev A, Georgievskaya A, Maier AB, Olsen A, Groth A, Simon AK, Brunet A, Jamil A, Kulaga A, Bhatti A, Yaden B, Pedersen BK, Schumacher B, Djordjevic B, Kennedy B, Chen C, Huang CY, Correll CU, Murphy CT, Ewald CY, Chen D, Valenzano DR, Sołdacki D, Erritzoe D, Meyer D, Sinclair DA, Chini EN, Teeling EC, Morgen E, Verdin E, Vernet E, Pinilla E, Fang EF, Bischof E, Mercken EM, Finger F, Kuipers F, Pun FW, Gyülveszi G, Civiletto G, Zmudze G, Blander G, Pincus HA, McClure J, Kirkland JL, Peyer J, Justice JN, Vijg J, Gruhn JR, McLaughlin J, Mannick J, Passos J, Baur JA, Betts-LaCroix J, Sedivy JM, Speakman JR, Shlain J, von Maltzahn J, Andreasson KI, Moody K, Palikaras K, Fortney K, Niedernhofer LJ, Rasmussen LJ, Veenhoff LM, Melton L, Ferrucci L, Quarta M, Koval M, Marinova M, Hamalainen M, Unfried M, Ringel MS, Filipovic M, Topors M, Mitin N, Roy N, Pintar N, Barzilai N, Binetti P, Singh P, Kohlhaas P, Robbins PD, Rubin P, Fedichev PO, Kamya P, Muñoz-Canoves P, de Cabo R, Faragher RGA, Konrad R, Ripa R, Mansukhani R, Büttner S, Wickström SA, Brunemeier S, Jakimov S, Luo S, Rosenzweig-Lipson S, Tsai SY, Dimmele… See abstract for full author list ➔ Lyu YX, et al. Among authors: wyss coray t. Aging (Albany NY). 2024 Oct 16;16(20):12955-12976. doi: 10.18632/aging.206135. Epub 2024 Oct 16. Aging (Albany NY). 2024. PMID: 39418098 Free PMC article. Review.
Augmentation of a neuroprotective myeloid state by hematopoietic cell transplantation.
Mader MM, Napole A, Wu D, Shibuya Y, Scavetti A, Foltz A, Atkins M, Hahn O, Yoo Y, Danziger R, Tan C, Wyss-Coray T, Steinman L, Wernig M. Mader MM, et al. bioRxiv [Preprint]. 2023 Mar 12:2023.03.10.532123. doi: 10.1101/2023.03.10.532123. bioRxiv. 2023. Update in: Nat Neurosci. 2024 May;27(5):901-912. doi: 10.1038/s41593-024-01609-3. PMID: 36945385 Free PMC article. Updated. Preprint.
267 results