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Page 1
Integrated proteomics spotlight the proteasome as a therapeutic vulnerability in embryonal tumors with multilayered rosettes.
Dottermusch M, Biabani A, Lempertz T, Schumann Y, Navolic J, Godbole S, Obrecht D, Frank S, Dorostkar MM, Voß H, Schlüter H, Rutkowski S, Schüller U, Neumann JE. Dottermusch M, et al. Among authors: dorostkar mm. Neuro Oncol. 2024 May 3;26(5):935-949. doi: 10.1093/neuonc/noad265. Neuro Oncol. 2024. PMID: 38158710 Free PMC article.
Molecular refinement of pilocytic astrocytoma in adult patients.
Bode H, Kresbach C, Holdhof D, Dorostkar MM, Harter PN, Hench J, Frank S, Suwala AK, Schweizer L, Eckhardt A, Neyazi S, Bockmayr M, Wefers AK, Schüller U. Bode H, et al. Among authors: dorostkar mm. Neuropathol Appl Neurobiol. 2023 Dec 19:e12949. doi: 10.1111/nan.12949. Online ahead of print. Neuropathol Appl Neurobiol. 2023. PMID: 38112165
Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level.
Godbole S, Voß H, Gocke A, Schlumbohm S, Schumann Y, Peng B, Mynarek M, Rutkowski S, Dottermusch M, Dorostkar MM, Korshunov A, Mair T, Pfister SM, Kwiatkowski M, Hotze M, Neumann P, Hartmann C, Weis J, Liesche-Starnecker F, Guan Y, Moritz M, Siebels B, Struve N, Schlüter H, Schüller U, Krisp C, Neumann JE. Godbole S, et al. Among authors: dorostkar mm. Nat Commun. 2024 Jul 24;15(1):6237. doi: 10.1038/s41467-024-50554-z. Nat Commun. 2024. PMID: 39043693 Free PMC article.
Update on quality assurance in neuropathology: Summary of the round robin trials on TERT promoter mutation, H3-3A mutation, 1p/19q codeletion, and KIAA1549::BRAF fusion testing in Germany in 2020 and 2021.
Pohl S, Dimitrova L, Grassow-Narlik M, Jöhrens K, Acker T, Dohmen H, Herms J, Dorostkar M, Hartmann C, Hasselblatt M, Neumann M, Reifenberger G, Felsberg J, Schüller U, Zoubaa S, Lorenz J, Rothhammer-Hampl T, Mauch-Mücke K, Riemenschneider MJ. Pohl S, et al. Clin Neuropathol. 2023 May-Jun;42(3):112-121. doi: 10.5414/NP301547. Clin Neuropathol. 2023. PMID: 36999511
Integrated analyses reveal two molecularly and clinically distinct subtypes of H3 K27M-mutant diffuse midline gliomas with prognostic significance.
Stegat L, Eckhardt A, Gocke A, Neyazi S, Pohl L, Schmid S, Dottermusch M, Frank S, Pinnschmidt H, Herms J, Glatzel M, Snuderl M, Schweizer L, Thomas C, Neumann J, Dorostkar MM, Schüller U, Wefers AK. Stegat L, et al. Among authors: dorostkar mm. Acta Neuropathol. 2024 Sep 10;148(1):40. doi: 10.1007/s00401-024-02800-3. Acta Neuropathol. 2024. PMID: 39256213 Free PMC article.
Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation.
Neyazi S, Yamazawa E, Hack K, Tanaka S, Nagae G, Kresbach C, Umeda T, Eckhardt A, Tatsuno K, Pohl L, Hana T, Bockmayr M, Kim P, Dorostkar MM, Takami T, Obrecht D, Takai K, Suwala AK, Komori T, Godbole S, Wefers AK, Otani R, Neumann JE, Higuchi F, Schweizer L, Nakanishi Y, Monoranu CM, Takami H, Engertsberger L, Yamada K, Ruf V, Nomura M, Mohme T, Mukasa A, Herms J, Takayanagi S, Mynarek M, Matsuura R, Lamszus K, Ishii K, Kluwe L, Imai H, von Deimling A, Koike T, Benesch M, Kushihara Y, Snuderl M, Nambu S, Frank S, Omura T, Hagel C, Kugasawa K, Mautner VF, Ichimura K, Rutkowski S, Aburatani H, Saito N, Schüller U. Neyazi S, et al. Among authors: dorostkar mm. Acta Neuropathol. 2024 Jan 24;147(1):22. doi: 10.1007/s00401-023-02668-9. Acta Neuropathol. 2024. PMID: 38265489 Free PMC article.
Adult intracranial ependymoma-relevance of DNA methylation profiling for diagnosis, prognosis, and treatment.
Träger M, Schweizer L, Pérez E, Schmid S, Hain EG, Dittmayer C, Onken J, Fukuoka K, Ichimura K, Schüller U, Dührsen L, Müther M, Paulus W, Thomas C, Gutt-Will M, Schucht P, Maragkou T, Schittenhelm J, Eckert F, Niyazi M, Fleischmann DF, Dorostkar MM, Feyer P, May SA, Moskopp D, Badakhshi H, Radke C, Walter J, Ehret F, Capper D, Kaul D. Träger M, et al. Among authors: dorostkar mm. Neuro Oncol. 2023 Jul 6;25(7):1286-1298. doi: 10.1093/neuonc/noad030. Neuro Oncol. 2023. PMID: 36734226 Free PMC article.
Single-nucleus chromatin accessibility profiling highlights distinct astrocyte signatures in progressive supranuclear palsy and corticobasal degeneration.
Briel N, Ruf VC, Pratsch K, Roeber S, Widmann J, Mielke J, Dorostkar MM, Windl O, Arzberger T, Herms J, Struebing FL. Briel N, et al. Among authors: dorostkar mm. Acta Neuropathol. 2022 Oct;144(4):615-635. doi: 10.1007/s00401-022-02483-8. Epub 2022 Aug 17. Acta Neuropathol. 2022. PMID: 35976433 Free PMC article.
63 results