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Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection.
Vetters J, van Helden M, De Nolf C, Rennen S, Cloots E, Van De Velde E, Fayazpour F, Van Moorleghem J, Vanheerswynghels M, Vergote K, Boon L, Vivier E, Lambrecht BN, Janssens S. Vetters J, et al. Among authors: boon l. iScience. 2023 Nov 23;26(12):108570. doi: 10.1016/j.isci.2023.108570. eCollection 2023 Dec 15. iScience. 2023. PMID: 38162021 Free PMC article.
A spatial architecture-embedding HLA signature to predict clinical response to immunotherapy in renal cell carcinoma.
Kinget L, Naulaerts S, Govaerts J, Vanmeerbeek I, Sprooten J, Laureano RS, Dubroja N, Shankar G, Bosisio FM, Roussel E, Verbiest A, Finotello F, Ausserhofer M, Lambrechts D, Boeckx B, Wozniak A, Boon L, Kerkhofs J, Zucman-Rossi J, Albersen M, Baldewijns M, Beuselinck B, Garg AD. Kinget L, et al. Among authors: boon l. Nat Med. 2024 Jun;30(6):1667-1679. doi: 10.1038/s41591-024-02978-9. Epub 2024 May 21. Nat Med. 2024. PMID: 38773341
Leukocyte-associated immunoglobulin-like receptor-1 blockade in combination with programmed death-ligand 1 targeting therapy mediates increased tumour control in mice.
Singh A, Mommers-Elshof ETAM, Vijver SV, Jansen JHM, Gonder S, Lebbink RJ, Bihan D, Farndale RW, Boon L, Langermann S, Leusen JHW, Flies D, Meyaard L, Pascoal Ramos MI. Singh A, et al. Among authors: boon l. Cancer Immunol Immunother. 2024 Jan 18;73(1):16. doi: 10.1007/s00262-023-03600-6. Cancer Immunol Immunother. 2024. PMID: 38236251 Free PMC article.
SHP-2 and PD-1-SHP-2 signaling regulate myeloid cell differentiation and antitumor responses.
Christofides A, Katopodi XL, Cao C, Karagkouni D, Aliazis K, Yenyuwadee S, Aksoylar HI, Pal R, Mahmoud MAA, Strauss L, Tijaro-Ovalle NM, Boon L, Asara J, Vlachos IS, Patsoukis N, Boussiotis VA. Christofides A, et al. Among authors: boon l. Nat Immunol. 2023 Jan;24(1):55-68. doi: 10.1038/s41590-022-01385-x. Epub 2022 Dec 29. Nat Immunol. 2023. PMID: 36581713 Free PMC article.
Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells.
Sprooten J, Vanmeerbeek I, Datsi A, Govaerts J, Naulaerts S, Laureano RS, Borràs DM, Calvet A, Malviya V, Kuballa M, Felsberg J, Sabel MC, Rapp M, Knobbe-Thomsen C, Liu P, Zhao L, Kepp O, Boon L, Tejpar S, Borst J, Kroemer G, Schlenner S, De Vleeschouwer S, Sorg RV, Garg AD. Sprooten J, et al. Among authors: boon l. Cell Rep Med. 2024 Jan 16;5(1):101377. doi: 10.1016/j.xcrm.2023.101377. Cell Rep Med. 2024. PMID: 38232703 Free PMC article.
Author Correction: A spatial architecture-embedding HLA signature to predict clinical response to immunotherapy in renal cell carcinoma.
Kinget L, Naulaerts S, Govaerts J, Vanmeerbeek I, Sprooten J, Laureano RS, Dubroja N, Shankar G, Bosisio FM, Roussel E, Verbiest A, Finotello F, Ausserhofer M, Lambrechts D, Boeckx B, Wozniak A, Boon L, Kerkhofs J, Zucman-Rossi J, Albersen M, Baldewijns M, Beuselinck B, Garg AD. Kinget L, et al. Among authors: boon l. Nat Med. 2024 Aug;30(8):2375-2376. doi: 10.1038/s41591-024-03174-5. Nat Med. 2024. PMID: 39009782 No abstract available.
Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma.
Verhoeven J, Jacobs KA, Rizzollo F, Lodi F, Hua Y, Poźniak J, Narayanan Srinivasan A, Houbaert D, Shankar G, More S, Schaaf MB, Dubroja Lakic N, Ganne M, Lamote J, Van Weyenbergh J, Boon L, Bechter O, Bosisio F, Uchiyama Y, Bertrand MJ, Marine JC, Lambrechts D, Bergers G, Agrawal M, Agostinis P. Verhoeven J, et al. Among authors: boon l. EMBO Mol Med. 2023 Dec 7;15(12):e18028. doi: 10.15252/emmm.202318028. Epub 2023 Nov 27. EMBO Mol Med. 2023. PMID: 38009521 Free PMC article.
601 results