Hu X - Search Results

1

Loss of Endothelial TDP-43 Leads to Blood Brain Barrier Defects in Mouse Models of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.

Cheemala A, Kimble AL, Tyburski JD, Leclair NK, Zuberi AR, Murphy M, Jellison ER, Reese B, Hu X, Lutz CM, Yan R, Murphy PA. Cheemala A, et al. Among authors: hu x. bioRxiv [Preprint]. 2023 Dec 14:2023.12.13.571184. doi: 10.1101/2023.12.13.571184. bioRxiv. 2023. PMID: 38168388 Free PMC article. Preprint.

2

Reversible overexpression of bace1-cleaved neuregulin-1 N-terminal fragment induces schizophrenia-like phenotypes in mice.

Luo X, He W, Hu X, Yan R. Luo X, et al. Among authors: hu x. Biol Psychiatry. 2014 Jul 15;76(2):120-7. doi: 10.1016/j.biopsych.2013.09.026. Epub 2013 Oct 5. Biol Psychiatry. 2014. PMID: 24210810 Free PMC article.

3

Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance.

Singh N, Das B, Zhou J, Hu X, Yan R. Singh N, et al. Among authors: hu x. Sci Adv. 2022 Jul 22;8(29):eabo3610. doi: 10.1126/sciadv.abo3610. Epub 2022 Jul 20. Sci Adv. 2022. PMID: 35857844 Free PMC article.

4

BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptides.

Zhou J, Singh N, Galske J, Hudobenko J, Hu X, Yan R. Zhou J, et al. Among authors: hu x. Mol Neurodegener. 2023 May 4;18(1):31. doi: 10.1186/s13024-023-00611-w. Mol Neurodegener. 2023. PMID: 37143090 Free PMC article.

5

The occurrence of aging-dependent reticulon 3 immunoreactive dystrophic neurites decreases cognitive function.

Shi Q, Hu X, Prior M, Yan R. Shi Q, et al. Among authors: hu x. J Neurosci. 2009 Apr 22;29(16):5108-15. doi: 10.1523/JNEUROSCI.5887-08.2009. J Neurosci. 2009. PMID: 19386906 Free PMC article.

6

The membrane topology of RTN3 and its effect on binding of RTN3 to BACE1.

He W, Shi Q, Hu X, Yan R. He W, et al. Among authors: hu x. J Biol Chem. 2007 Oct 5;282(40):29144-51. doi: 10.1074/jbc.M704181200. Epub 2007 Aug 15. J Biol Chem. 2007. PMID: 17699523 Free article.

7

Neurological dysfunctions associated with altered BACE1-dependent Neuregulin-1 signaling.

Hu X, Fan Q, Hou H, Yan R. Hu X, et al. J Neurochem. 2016 Jan;136(2):234-49. doi: 10.1111/jnc.13395. Epub 2015 Nov 13. J Neurochem. 2016. PMID: 26465092 Free PMC article. Review.

8

RTN1 and RTN3 protein are differentially associated with senile plaques in Alzheimer's brains.

Shi Q, Ge Y, He W, Hu X, Yan R. Shi Q, et al. Among authors: hu x. Sci Rep. 2017 Jul 21;7(1):6145. doi: 10.1038/s41598-017-05504-9. Sci Rep. 2017. PMID: 28733667 Free PMC article.

9

BACE1 deletion in the adult mouse reverses preformed amyloid deposition and improves cognitive functions.

Hu X, Das B, Hou H, He W, Yan R. Hu X, et al. J Exp Med. 2018 Mar 5;215(3):927-940. doi: 10.1084/jem.20171831. Epub 2018 Feb 14. J Exp Med. 2018. PMID: 29444819 Free PMC article.

10

Mapping of interaction domains mediating binding between BACE1 and RTN/Nogo proteins.

He W, Hu X, Shi Q, Zhou X, Lu Y, Fisher C, Yan R. He W, et al. Among authors: hu x. J Mol Biol. 2006 Oct 27;363(3):625-34. doi: 10.1016/j.jmb.2006.07.094. Epub 2006 Aug 11. J Mol Biol. 2006. PMID: 16979658

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