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Presence of onco-fetal neighborhoods in hepatocellular carcinoma is associated with relapse and response to immunotherapy.
Li Z, Pai R, Gupta S, Currenti J, Guo W, Di Bartolomeo A, Feng H, Zhang Z, Li Z, Liu L, Singh A, Bai Y, Yang B, Mishra A, Yang K, Qiao L, Wallace M, Yin Y, Xia Q, Chan JKY, George J, Chow PK, Ginhoux F, Sharma A. Li Z, et al. Among authors: ginhoux f. Nat Cancer. 2024 Jan;5(1):167-186. doi: 10.1038/s43018-023-00672-2. Epub 2024 Jan 2. Nat Cancer. 2024. PMID: 38168935
Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2.
McGovern N, Shin A, Low G, Low D, Duan K, Yao LJ, Msallam R, Low I, Shadan NB, Sumatoh HR, Soon E, Lum J, Mok E, Hubert S, See P, Kunxiang EH, Lee YH, Janela B, Choolani M, Mattar CNZ, Fan Y, Lim TKH, Chan DKH, Tan KK, Tam JKC, Schuster C, Elbe-Bürger A, Wang XN, Bigley V, Collin M, Haniffa M, Schlitzer A, Poidinger M, Albani S, Larbi A, Newell EW, Chan JKY, Ginhoux F. McGovern N, et al. Among authors: ginhoux f. Nature. 2017 Jun 29;546(7660):662-666. doi: 10.1038/nature22795. Epub 2017 Jun 14. Nature. 2017. PMID: 28614294 Free PMC article.
Deciphering human macrophage development at single-cell resolution.
Bian Z, Gong Y, Huang T, Lee CZW, Bian L, Bai Z, Shi H, Zeng Y, Liu C, He J, Zhou J, Li X, Li Z, Ni Y, Ma C, Cui L, Zhang R, Chan JKY, Ng LG, Lan Y, Ginhoux F, Liu B. Bian Z, et al. Among authors: ginhoux f. Nature. 2020 Jun;582(7813):571-576. doi: 10.1038/s41586-020-2316-7. Epub 2020 May 20. Nature. 2020. PMID: 32499656
Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma.
Sharma A, Seow JJW, Dutertre CA, Pai R, Blériot C, Mishra A, Wong RMM, Singh GSN, Sudhagar S, Khalilnezhad S, Erdal S, Teo HM, Khalilnezhad A, Chakarov S, Lim TKH, Fui ACY, Chieh AKW, Chung CP, Bonney GK, Goh BK, Chan JKY, Chow PKH, Ginhoux F, DasGupta R. Sharma A, et al. Among authors: ginhoux f. Cell. 2020 Oct 15;183(2):377-394.e21. doi: 10.1016/j.cell.2020.08.040. Epub 2020 Sep 24. Cell. 2020. PMID: 32976798 Free article.
Single-Cell RNA-seq Reveals Angiotensin-Converting Enzyme 2 and Transmembrane Serine Protease 2 Expression in TROP2+ Liver Progenitor Cells: Implications in Coronavirus Disease 2019-Associated Liver Dysfunction.
Seow JJW, Pai R, Mishra A, Shepherdson E, Lim TKH, Goh BKP, Chan JKY, Chow PKH, Ginhoux F, DasGupta R, Sharma A. Seow JJW, et al. Among authors: ginhoux f. Front Med (Lausanne). 2021 Apr 22;8:603374. doi: 10.3389/fmed.2021.603374. eCollection 2021. Front Med (Lausanne). 2021. PMID: 33968947 Free PMC article.
Microbial exposure during early human development primes fetal immune cells.
Mishra A, Lai GC, Yao LJ, Aung TT, Shental N, Rotter-Maskowitz A, Shepherdson E, Singh GSN, Pai R, Shanti A, Wong RMM, Lee A, Khyriem C, Dutertre CA, Chakarov S, Srinivasan KG, Shadan NB, Zhang XM, Khalilnezhad S, Cottier F, Tan ASM, Low G, Chen P, Fan Y, Hor PX, Lee AKM, Choolani M, Vermijlen D, Sharma A, Fuks G, Straussman R, Pavelka N, Malleret B, McGovern N, Albani S, Chan JKY, Ginhoux F. Mishra A, et al. Among authors: ginhoux f. Cell. 2021 Jun 24;184(13):3394-3409.e20. doi: 10.1016/j.cell.2021.04.039. Epub 2021 Jun 1. Cell. 2021. PMID: 34077752 Free PMC article.
Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease.
Mulder K, Patel AA, Kong WT, Piot C, Halitzki E, Dunsmore G, Khalilnezhad S, Irac SE, Dubuisson A, Chevrier M, Zhang XM, Tam JKC, Lim TKH, Wong RMM, Pai R, Khalil AIS, Chow PKH, Wu SZ, Al-Eryani G, Roden D, Swarbrick A, Chan JKY, Albani S, Derosa L, Zitvogel L, Sharma A, Chen J, Silvin A, Bertoletti A, Blériot C, Dutertre CA, Ginhoux F. Mulder K, et al. Among authors: ginhoux f. Immunity. 2021 Aug 10;54(8):1883-1900.e5. doi: 10.1016/j.immuni.2021.07.007. Epub 2021 Jul 30. Immunity. 2021. PMID: 34331874 Free article.
A subset of Kupffer cells regulates metabolism through the expression of CD36.
Blériot C, Barreby E, Dunsmore G, Ballaire R, Chakarov S, Ficht X, De Simone G, Andreata F, Fumagalli V, Guo W, Wan G, Gessain G, Khalilnezhad A, Zhang XM, Ang N, Chen P, Morgantini C, Azzimato V, Kong WT, Liu Z, Pai R, Lum J, Shihui F, Low I, Xu C, Malleret B, Kairi MFM, Balachander A, Cexus O, Larbi A, Lee B, Newell EW, Ng LG, Phoo WW, Sobota RM, Sharma A, Howland SW, Chen J, Bajenoff M, Yvan-Charvet L, Venteclef N, Iannacone M, Aouadi M, Ginhoux F. Blériot C, et al. Among authors: ginhoux f. Immunity. 2021 Sep 14;54(9):2101-2116.e6. doi: 10.1016/j.immuni.2021.08.006. Epub 2021 Aug 31. Immunity. 2021. PMID: 34469775 Free article.
Reply to Over-celling fetal microbial exposure.
Mishra A, Yao LJ, Wasser M, Khyriem C, Malleret B, McGovern N, Albani S, Chan JKY, Ginhoux F. Mishra A, et al. Among authors: ginhoux f. Cell. 2021 Nov 24;184(24):5842-5844. doi: 10.1016/j.cell.2021.10.028. Cell. 2021. PMID: 34822780 Free article. No abstract available.
382 results