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Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML.
Wheeler EC, Martin BJE, Doyle WC, Neaher S, Conway CA, Pitton CN, Gorelov RA, Donahue M, Jann JC, Abdel-Wahab O, Taylor J, Seiler M, Buonamici S, Pikman Y, Garcia JS, Belizaire R, Adelman K, Tothova Z. Wheeler EC, et al. Among authors: martin bje. Sci Transl Med. 2024 Jan 3;16(728):eade2774. doi: 10.1126/scitranslmed.ade2774. Epub 2024 Jan 3. Sci Transl Med. 2024. PMID: 38170787 Free PMC article.
ecDNA party bus: Bringing the enhancer to you.
Adelman K, Martin BJE. Adelman K, et al. Among authors: martin bje. Mol Cell. 2021 May 6;81(9):1866-1867. doi: 10.1016/j.molcel.2021.04.017. Mol Cell. 2021. PMID: 33961776 Free article.
Oncogenic CDK13 mutations impede nuclear RNA surveillance.
Insco ML, Abraham BJ, Dubbury SJ, Kaltheuner IH, Dust S, Wu C, Chen KY, Liu D, Bellaousov S, Cox AM, Martin BJE, Zhang T, Ludwig CG, Fabo T, Modhurima R, Esgdaille DE, Henriques T, Brown KM, Chanock SJ, Geyer M, Adelman K, Sharp PA, Young RA, Boutz PL, Zon LI. Insco ML, et al. Among authors: martin bje. Science. 2023 Apr 21;380(6642):eabn7625. doi: 10.1126/science.abn7625. Epub 2023 Apr 21. Science. 2023. PMID: 37079685 Free PMC article.
Pterostilbene leads to DNMT3B-mediated DNA methylation and silencing of OCT1-targeted oncogenes in breast cancer cells.
Beetch M, Boycott C, Harandi-Zadeh S, Yang T, Martin BJE, Dixon-McDougall T, Ren K, Gacad A, Dupuis JH, Ullmer M, Lubecka K, Yada RY, Brown CJ, Howe LJ, Stefanska B. Beetch M, et al. Among authors: martin bje. J Nutr Biochem. 2021 Dec;98:108815. doi: 10.1016/j.jnutbio.2021.108815. Epub 2021 Jul 7. J Nutr Biochem. 2021. PMID: 34242723 Free PMC article.
19 results