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Page 1
Spatial analysis of NOS2 and COX2 interaction with T-effector cells reveals immunosuppressive landscapes associated with poor outcome in ER- breast cancer patients.
Ridnour LA, Cheng RYS, Heinz WF, Pore M, Gonzalez AL, Femino EL, Moffat R, Wink AL, Imtiaz F, Coutinho L, Butcher D, Edmondson EF, Rangel MC, Wong STC, Lipkowitz S, Glynn S, Vitek MP, McVicar DW, Li X, Anderson SK, Paolocci N, Hewitt SM, Ambs S, Billiar TR, Chang JC, Lockett SJ, Wink DA. Ridnour LA, et al. Among authors: butcher d. bioRxiv [Preprint]. 2023 Dec 23:2023.12.21.572867. doi: 10.1101/2023.12.21.572867. bioRxiv. 2023. PMID: 38187660 Free PMC article. Preprint.
Interferon-gamma is Quintessential for NOS2 and COX2 Expression in ER - Breast Tumors that Lead to Poor Outcome.
Cheng RY, Ridnour LA, Wink AL, Gonzalez AL, Femino EL, Rittscher H, Somasundarum V, Heinz WF, Coutinho L, Cristina Rangel M, Edmondson EF, Butcher D, Kinders RJ, Li X, Wong STC, McVicar DW, Anderson SK, Pore M, Hewitt SM, Billiar TR, Glynn S, Chang JC, Lockett SJ, Ambs S, Wink DA. Cheng RY, et al. Among authors: butcher d. bioRxiv [Preprint]. 2023 Apr 6:2023.04.06.535916. doi: 10.1101/2023.04.06.535916. bioRxiv. 2023. Update in: Cell Death Dis. 2023 May 11;14(5):319. doi: 10.1038/s41419-023-05834-9 PMID: 37066331 Free PMC article. Updated. Preprint.
NOS2 and COX2 Provide Key Spatial Targets that Determine Outcome in ER- Breast Cancer.
Ridnour LA, Heinz WF, Cheng RY, Wink AL, Kedei N, Pore M, Imtiaz F, Femino EL, Gonzalez AL, Coutinho L, Butcher D, Edmondson EF, Rangel MC, Kinders RJ, Lipkowitz S, Wong ST, Anderson SK, McVicar DW, Li X, Glynn SA, Billiar TR, Chang JC, Hewitt SM, Ambs S, Lockett SJ, Wink DA. Ridnour LA, et al. Among authors: butcher d. bioRxiv [Preprint]. 2023 Dec 23:2023.12.21.572859. doi: 10.1101/2023.12.21.572859. bioRxiv. 2023. PMID: 38187532 Free PMC article. Preprint.
Metastatic organotropism in small cell lung cancer.
Krishnamurthy M, Dhall A, Schultz CW, Baird MA, Desai P, Odell J, Sahoo S, Takahashi N, Nirula M, Zhuang S, Huang Y, Schroeder B, Zhang Y, Thomas MS, Redon C, Robinson C, Thang L, Ileva L, Patel NL, Kalen JD, Varlet AA, Zuela-Sopilniak N, Jha A, Wangsa D, Butcher D, Morgan T, Afzal AN, Chari R, Baktiar K, Kumar S, Pongor L, Difilippantonio S, Aladjem MI, Pommier Y, Jolly MK, Lammerding J, Sharma AK, Thomas A. Krishnamurthy M, et al. Among authors: butcher d. bioRxiv [Preprint]. 2024 Oct 8:2024.10.07.617066. doi: 10.1101/2024.10.07.617066. bioRxiv. 2024. PMID: 39416100 Free PMC article. Preprint.
Tumor NOS2 and COX2 Spatial Juxtaposition with CD8+ T Cells Promote Metastatic and Cancer Stem Cell Niches that Lead to Poor Outcome in ER- Breast Cancer.
Ridnour LA, Heinz WF, Cheng RYS, Wink AL, Kedei N, Pore M, Imtiaz F, Femino EL, Gonzalez AL, Coutinho LL, Moffat RL, Butcher D, Edmondson EF, Li X, Rangel MC, Kinders RJ, Rittscher J, Lipkowitz S, Wong STC, Anderson SK, McVicar DW, Glynn SA, Billiar TR, Chang JC, Hewitt SM, Ambs S, Lockett SJ, Wink DA. Ridnour LA, et al. Among authors: butcher d. Cancer Res Commun. 2024 Oct 1;4(10):2766-2782. doi: 10.1158/2767-9764.CRC-24-0235. Cancer Res Commun. 2024. PMID: 39356141 Free PMC article.
Study APV20002: Safety and Efficacy Results Through Week 684 for Pediatric Participants Living with HIV-1 Treated with Ritonavir-Boosted Fosamprenavir Oral Solution-Based Antiretroviral Therapy.
Ross LL, Cotton MF, Cassim H, Garges HP, van Dijkman SC, Morarji K, Karthika S, Danehower S, Radford J, Butcher D. Ross LL, et al. Among authors: butcher d. AIDS Res Hum Retroviruses. 2024 Oct;40(10):606-613. doi: 10.1089/AID.2024.0020. Epub 2024 Jul 19. AIDS Res Hum Retroviruses. 2024. PMID: 38973446
Stratified analyses refine association between TLR7 rare variants and severe COVID-19.
Boos J, van der Made CI, Ramakrishnan G, Coughlan E, Asselta R, Löscher BS, Valenti LVC, de Cid R, Bujanda L, Julià A, Pairo-Castineira E, Baillie JK, May S, Zametica B, Heggemann J, Albillos A, Banales JM, Barretina J, Blay N, Bonfanti P, Buti M, Fernandez J, Marsal S, Prati D, Ronzoni L, Sacchi N; Spanish/Italian Severe COVID-19 Sequencing group; GenOMICC Investigators; Schultze JL, Riess O, Franke A, Rawlik K, Ellinghaus D, Hoischen A, Schmidt A, Ludwig KU. Boos J, et al. HGG Adv. 2024 Oct 10;5(4):100323. doi: 10.1016/j.xhgg.2024.100323. Epub 2024 Jun 28. HGG Adv. 2024. PMID: 38944683 Free PMC article.
Adjuvant COX inhibition augments STING signaling and cytolytic T cell infiltration in irradiated 4T1 tumors.
Ridnour LA, Cheng RY, Kedei N, Somasundaram V, Bhattacharyya DD, Basudhar D, Wink AL, Walke AJ, Kim C, Heinz WF, Edmondson EF, Butcher DO, Warner AC, Dorsey TH, Pore M, Kinders RJ, Lipkowitz S, Bryant RJ, Rittscher J, Wong ST, Hewitt SM, Chang JC, Shalaby A, Callagy GM, Glynn SA, Ambs S, Anderson SK, McVicar DW, Lockett SJ, Wink DA. Ridnour LA, et al. Among authors: butcher do. JCI Insight. 2024 May 21;9(12):e165356. doi: 10.1172/jci.insight.165356. JCI Insight. 2024. PMID: 38912586 Free PMC article.
241 results