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Bioisosteric analogs of MDMA: Improving the pharmacological profile?
Alberto-Silva AS, Hemmer S, Bock HA, da Silva LA, Scott KR, Kastner N, Bhatt M, Niello M, Jäntsch K, Kudlacek O, Bossi E, Stockner T, Meyer MR, McCorvy JD, Brandt SD, Kavanagh P, Sitte HH. Alberto-Silva AS, et al. Among authors: niello m. J Neurochem. 2024 Sep;168(9):2022-2042. doi: 10.1111/jnc.16149. Epub 2024 Jun 19. J Neurochem. 2024. PMID: 38898705
Identification of the potassium-binding site in serotonin transporter.
Hellsberg E, Boytsov D, Chen Q, Niello M, Freissmuth M, Rudnick G, Zhang YW, Sandtner W, Forrest LR. Hellsberg E, et al. Among authors: niello m. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2319384121. doi: 10.1073/pnas.2319384121. Epub 2024 Apr 23. Proc Natl Acad Sci U S A. 2024. PMID: 38652746 Free PMC article.
Bioisosteric analogs of MDMA with improved pharmacological profile.
Alberto-Silva AS, Hemmer S, Bock HA, Alves da Silva L, Scott KR, Kastner N, Bhatt M, Niello M, Jäntsch K, Kudlacek O, Bossi E, Stockner T, Meyer MR, McCorvy JD, Brandt SD, Kavanagh P, Sitte HH. Alberto-Silva AS, et al. Among authors: niello m. bioRxiv [Preprint]. 2024 Apr 11:2024.04.08.588083. doi: 10.1101/2024.04.08.588083. bioRxiv. 2024. Update in: J Neurochem. 2024 Sep;168(9):2022-2042. doi: 10.1111/jnc.16149 PMID: 38645142 Free PMC article. Updated. Preprint.
Structure-activity relationships of serotonergic 5-MeO-DMT derivatives: insights into psychoactive and thermoregulatory properties.
Puigseslloses P, Nadal-Gratacós N, Ketsela G, Weiss N, Berzosa X, Estrada-Tejedor R, Islam MN, Holy M, Niello M, Pubill D, Camarasa J, Escubedo E, Sitte HH, López-Arnau R. Puigseslloses P, et al. Among authors: niello m. Mol Psychiatry. 2024 Aug;29(8):2346-2358. doi: 10.1038/s41380-024-02506-8. Epub 2024 Mar 14. Mol Psychiatry. 2024. PMID: 38486047 Free PMC article.
Development and validation of an automated microfluidic perfusion platform for parallelized screening of compounds in vitro.
Brugnoli FR, Holy M, Niello M, Maier J, Hanreich M, Menzel M, Haberler M, Zulus N, Pickl T, Ivanova C, Muiznieks LD, Garlan B, Sitte HH. Brugnoli FR, et al. Among authors: niello m. Basic Clin Pharmacol Toxicol. 2023 Nov;133(5):535-547. doi: 10.1111/bcpt.13940. Epub 2023 Sep 17. Basic Clin Pharmacol Toxicol. 2023. PMID: 37658634 Free PMC article.
Persistent binding at dopamine transporters determines sustained psychostimulant effects.
Niello M, Sideromenos S, Gradisch R, O Shea R, Schwazer J, Maier J, Kastner N, Sandtner W, Jäntsch K, Lupica CR, Hoffman AF, Lubec G, Loland CJ, Stockner T, Pollak DD, Baumann MH, Sitte HH. Niello M, et al. Proc Natl Acad Sci U S A. 2023 Feb 7;120(6):e2114204120. doi: 10.1073/pnas.2114204120. Epub 2023 Feb 2. Proc Natl Acad Sci U S A. 2023. PMID: 36730201 Free PMC article.
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