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Page 1
Cognitive reserve against Alzheimer's pathology is linked to brain activity during memory formation.
Vockert N, Machts J, Kleineidam L, Nemali A, Incesoy EI, Bernal J, Schütze H, Yakupov R, Peters O, Gref D, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Rostamzadeh A, Glanz W, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Spottke A, Roy N, Heneka MT, Brosseron F, Wagner M, Wolfsgruber S, Dobisch L, Dechent P, Hetzer S, Scheffler K, Zeidman P, Stern Y, Schott BH, Jessen F, Düzel E, Maass A, Ziegler G; DELCODE study group. Vockert N, et al. Among authors: wolfsgruber s. Nat Commun. 2024 Nov 13;15(1):9815. doi: 10.1038/s41467-024-53360-9. Nat Commun. 2024. PMID: 39537609 Free PMC article.
Association of Neurogranin and BACE1 With Clinical Cognitive Decline in Individuals With Subjective Cognitive Decline.
Wang X, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Hansen N, Jessen F, Rostamzadeh A, Duzel E, Glanz W, Incesoy EI, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann BS, Teipel SJ, Kilimann I, Goerss D, Laske C, Munk MHJ, Spottke A, Roy-Kluth N, Heneka MT, Brosseron F, Wagner M, Wolfsgruber S, Ramirez A, Kleineidam L, Stark M, Peters O. Wang X, et al. Among authors: wolfsgruber s. Neurology. 2024 Oct 22;103(8):e209806. doi: 10.1212/WNL.0000000000209806. Epub 2024 Sep 20. Neurology. 2024. PMID: 39303184
Mid- and late-life lifestyle activities as main drivers of general and domain-specific cognitive reserve in individuals with Parkinson's disease: cross-sectional and longitudinal evidence from the LANDSCAPE study.
Ophey A, Wirtz K, Wolfsgruber S, Balzer-Geldsetzer M, Berg D, Hilker-Roggendorf R, Kassubek J, Liepelt-Scarfone I, Becker S, Mollenhauer B, Reetz K, Riedel O, Schulz JB, Storch A, Trenkwalder C, Witt K, Wittchen HU, Dodel R, Roeske S, Kalbe E. Ophey A, et al. Among authors: wolfsgruber s. J Neurol. 2024 Aug;271(8):5411-5424. doi: 10.1007/s00415-024-12484-0. Epub 2024 Jul 1. J Neurol. 2024. PMID: 38951175 Free PMC article.
Plasma amyloid beta X-42/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease.
Vogelgsang J, Hansen N, Stark M, Wagner M, Klafki H, Morgado BM, Jahn-Brodmann A, Schott B, Esselmann H, Bauer C, Schuchhardt J, Kleineidam L, Wolfsgruber S, Peters O, Schneider LS, Wang X, Menne F, Priller J, Spruth E, Altenstein S, Lohse A, Schneider A, Fliessbach K, Vogt I, Bartels C, Jessen F, Rostamzadeh A, Duezel E, Glanz W, Incesoy E, Butryn M, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann B, Guersel S, Teipel S, Kilimann I, Goerss D, Laske C, Munk M, Sanzenbacher C, Spottke A, Roy-Kluth N, Heneka M, Brosseron F, Ramierez A, Schmid M, Wiltfang J. Vogelgsang J, et al. Among authors: wolfsgruber s. Alzheimers Dement. 2024 Aug;20(8):5132-5142. doi: 10.1002/alz.13909. Epub 2024 Jun 28. Alzheimers Dement. 2024. PMID: 38940303 Free PMC article.
Symptomatic Clusters Related to Amyloid Positivity in Cognitively Unimpaired Individuals.
Sannemann L, Bartels C, Brosseron F, Buerger K, Fliessbach K, Freiesleben SD, Frommann I, Glanz W, Heneka MT, Janowitz D, Kilimann I, Kleineidam L, Lammerding D, Laske C, Munk MHJ, Perneczky R, Peters O, Priller J, Rauchmann BS, Rostamzadeh A, Roy-Kluth N, Schild AK, Schneider A, Schneider LS, Spottke A, Spruth EJ, Teipel S, Wagner M, Wiltfang J, Wolfsgruber S, Duezel E, Jessen F; DELCODE Study Group. Sannemann L, et al. Among authors: wolfsgruber s. J Alzheimers Dis. 2024;100(1):193-205. doi: 10.3233/JAD-231335. J Alzheimers Dis. 2024. PMID: 38848176
Aβ oligomers peak in early stages of Alzheimer's disease preceding tau pathology.
Blömeke L, Rehn F, Kraemer-Schulien V, Kutzsche J, Pils M, Bujnicki T, Lewczuk P, Kornhuber J, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Lohse A, Schneider A, Fliessbach K, Wiltfang J, Hansen N, Rostamzadeh A, Düzel E, Glanz W, Incesoy EI, Butryn M, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Sanzenbacher C, Spottke A, Roy-Kluth N, Heneka MT, Brosseron F, Wagner M, Wolfsgruber S, Kleineidam L, Stark M, Schmid M, Jessen F, Bannach O, Willbold D, Peters O. Blömeke L, et al. Among authors: wolfsgruber s. Alzheimers Dement (Amst). 2024 Apr 25;16(2):e12589. doi: 10.1002/dad2.12589. eCollection 2024 Apr-Jun. Alzheimers Dement (Amst). 2024. PMID: 38666085 Free PMC article.
A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings.
Baumeister H, Vogel JW, Insel PS, Kleineidam L, Wolfsgruber S, Stark M, Gellersen HM, Yakupov R, Schmid MC, Lüsebrink F, Brosseron F, Ziegler G, Freiesleben SD, Preis L, Schneider LS, Spruth EJ, Altenstein S, Lohse A, Fliessbach K, Vogt IR, Bartels C, Schott BH, Rostamzadeh A, Glanz W, Incesoy EI, Butryn M, Janowitz D, Rauchmann BS, Kilimann I, Goerss D, Munk MH, Hetzer S, Dechent P, Ewers M, Scheffler K, Wuestefeld A, Strandberg O, van Westen D, Mattsson-Carlgren N, Janelidze S, Stomrud E, Palmqvist S, Spottke A, Laske C, Teipel S, Perneczky R, Buerger K, Schneider A, Priller J, Peters O, Ramirez A, Wiltfang J, Heneka MT, Wagner M, Düzel E, Jessen F, Hansson O, Berron D. Baumeister H, et al. Among authors: wolfsgruber s. Brain. 2024 Jul 5;147(7):2400-2413. doi: 10.1093/brain/awae118. Brain. 2024. PMID: 38654513 Free PMC article.
Machine Learning-Based Perivascular Space Volumetry in Alzheimer Disease.
Deike K, Decker A, Scheyhing P, Harten J, Zimmermann N, Paech D, Peters O, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth E, Altenstein S, Lohse A, Fliessbach K, Kimmich O, Wiltfang J, Bartels C, Hansen N, Jessen F, Rostamzadeh A, Düzel E, Glanz W, Incesoy EI, Butryn M, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Spottke A, Roy N, Wagner M, Roeske S, Heneka MT, Brosseron F, Ramirez A, Dobisch L, Wolfsgruber S, Kleineidam L, Yakupov R, Stark M, Schmid MC, Berger M, Hetzer S, Dechent P, Scheffler K, Petzold GC, Schneider A, Effland A, Radbruch A. Deike K, et al. Among authors: wolfsgruber s. Invest Radiol. 2024 Sep 1;59(9):667-676. doi: 10.1097/RLI.0000000000001077. Epub 2024 Apr 23. Invest Radiol. 2024. PMID: 38652067
Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition.
Hayek D, Ziegler G, Kleineidam L, Brosseron F, Nemali A, Vockert N, Ravichandran KA, Betts MJ, Peters O, Schneider LS, Wang X, Priller J, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Bartels C, Rostamzadeh A, Glanz W, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Laske C, Mengel D, Synofzik M, Munk MH, Spottke A, Roy N, Roeske S, Kuhn E, Ramirez A, Dobisch L, Schmid M, Berger M, Wolfsgruber S, Yakupov R, Hetzer S, Dechent P, Ewers M, Scheffler K, Schott BH, Schreiber S, Orellana A, de Rojas I, Marquié M, Boada M, Sotolongo O, González PG, Puerta R, Düzel E, Jessen F, Wagner M, Ruiz A, Heneka MT, Maass A. Hayek D, et al. Among authors: wolfsgruber s. Mol Psychiatry. 2024 Apr;29(4):992-1004. doi: 10.1038/s41380-023-02387-3. Epub 2024 Jan 12. Mol Psychiatry. 2024. PMID: 38216727 Free PMC article.
Association of latent factors of neuroinflammation with Alzheimer's disease pathology and longitudinal cognitive decline.
Teipel SJ, Dyrba M, Kleineidam L, Brosseron F, Levin F, Bruno D, Buerger K, Cosma N, Schneider LS, Düzel E, Glanz W, Fliessbach K, Janowitz D, Kilimann I, Laske C, Munk MH, Maier F, Peters O, Pomara N, Perneczky R, Rauchmann BS, Priller J, Ramirez A, Roy N, Schneider A, Spottke A, Spruth EJ, Roeske S, Wagner M, Wiltfang J, Wolfsgruber S, Bartels C, Jessen F, Heneka MT; DELCODE study group and the Alzheimer´s Disease Neuroimaging Initiative. Teipel SJ, et al. Among authors: wolfsgruber s. Alzheimers Dement (Amst). 2024 Jan 10;16(1):e12510. doi: 10.1002/dad2.12510. eCollection 2024 Jan-Mar. Alzheimers Dement (Amst). 2024. PMID: 38213951 Free PMC article.
113 results