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Page 1
ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition.
Borenäs M, Umapathy G, Lind DE, Lai WY, Guan J, Johansson J, Jennische E, Schmidt A, Kurhe Y, Gabre JL, Aniszewska A, Strömberg A, Bemark M, Hall MN, Eynden JVD, Hallberg B, Palmer RH. Borenäs M, et al. Among authors: gabre jl. Proc Natl Acad Sci U S A. 2024 Jan 2;121(1):e2315242121. doi: 10.1073/pnas.2315242121. Epub 2023 Dec 28. Proc Natl Acad Sci U S A. 2024. PMID: 38154064 Free PMC article.
ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression.
Chuang TP, Lai WY, Gabre JL, Lind DE, Umapathy G, Bokhari AA, Bergman B, Kristenson L, Thorén FB, Le A, Doebele RC, Van den Eynden J, Palmer RH, Hallberg B. Chuang TP, et al. Among authors: gabre jl. Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2216479120. doi: 10.1073/pnas.2216479120. Epub 2023 Feb 15. Proc Natl Acad Sci U S A. 2023. PMID: 36791109 Free PMC article.
Novel human-derived EML4-ALK fusion cell lines identify ribonucleotide reductase RRM2 as a target of activated ALK in NSCLC.
Bokhari AA, Lai WY, Le AT, Gabre JL, Chuang TP, Fransson S, Bergman B, Djos A, Chen N, Martinsson T, Van den Eynden J, Doebele RC, Palmer RH, Hallberg B, Umapathy G. Bokhari AA, et al. Among authors: gabre jl. Lung Cancer. 2022 Sep;171:103-114. doi: 10.1016/j.lungcan.2022.07.010. Epub 2022 Jul 25. Lung Cancer. 2022. PMID: 35933914 Free article.
Loss of RET Promotes Mesenchymal Identity in Neuroblastoma Cells.
Siaw JT, Gabre JL, Uçkun E, Vigny M, Zhang W, Van den Eynden J, Hallberg B, Palmer RH, Guan J. Siaw JT, et al. Among authors: gabre jl. Cancers (Basel). 2021 Apr 15;13(8):1909. doi: 10.3390/cancers13081909. Cancers (Basel). 2021. PMID: 33921066 Free PMC article.