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Increasing HbA1c is associated with reduced CD8+ T cell functionality in response to influenza virus in a TCR-dependent manner in individuals with diabetes mellitus.
Hulme KD, Tong ZWM, Rowntree LC, van de Sandt CE, Ronacher K, Grant EJ, Dorey ES, Gallo LA, Gras S, Kedzierska K, Barrett HL, Short KR. Hulme KD, et al. Among authors: gras s. Cell Mol Life Sci. 2024 Jan 12;81(1):35. doi: 10.1007/s00018-023-05010-4. Cell Mol Life Sci. 2024. PMID: 38214784 Free PMC article.
Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.
Valkenburg SA, Gras S, Guillonneau C, La Gruta NL, Thomas PG, Purcell AW, Rossjohn J, Doherty PC, Turner SJ, Kedzierska K. Valkenburg SA, et al. Among authors: gras s. PLoS Pathog. 2010 Aug 12;6(8):e1001039. doi: 10.1371/journal.ppat.1001039. PLoS Pathog. 2010. PMID: 20711359 Free PMC article.
Preemptive priming readily overcomes structure-based mechanisms of virus escape.
Valkenburg SA, Gras S, Guillonneau C, Hatton LA, Bird NA, Twist KA, Halim H, Jackson DC, Purcell AW, Turner SJ, Doherty PC, Rossjohn J, Kedzierska K. Valkenburg SA, et al. Among authors: gras s. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5570-5. doi: 10.1073/pnas.1302935110. Epub 2013 Mar 14. Proc Natl Acad Sci U S A. 2013. PMID: 23493558 Free PMC article.
Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities.
Quiñones-Parra S, Grant E, Loh L, Nguyen TH, Campbell KA, Tong SY, Miller A, Doherty PC, Vijaykrishna D, Rossjohn J, Gras S, Kedzierska K. Quiñones-Parra S, et al. Among authors: gras s. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1049-54. doi: 10.1073/pnas.1322229111. Epub 2014 Jan 6. Proc Natl Acad Sci U S A. 2014. PMID: 24395804 Free PMC article.
389 results