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Activation of coagulation FXI promotes endothelial inflammation and amplifies platelet activation in a nonhuman primate model of hyperlipidemia.
Kohs TCL, Vu HH, Jordan KR, Parra-Izquierdo I, Hinds MT, Shatzel JJ, Kievit P, Morgan TK, Yunga ST, Ngo TTM, Aslan JE, Wallisch M, Lorentz CU, Tucker EI, Gailani D, Lindner JR, Puy C, McCarty OJT. Kohs TCL, et al. Among authors: hinds mt. Res Pract Thromb Haemost. 2023 Nov 27;8(1):102276. doi: 10.1016/j.rpth.2023.102276. eCollection 2024 Jan. Res Pract Thromb Haemost. 2023. PMID: 38226339 Free PMC article.
Measurement science in the circulatory system.
Jones CM, Baker-Groberg SM, Cianchetti FA, Glynn JJ, Healy LD, Lam WY, Nelson JW, Parrish DC, Phillips KG, Scott-Drechsel DE, Tagge IJ, Zelaya JE, Hinds MT, McCarty OJ. Jones CM, et al. Among authors: hinds mt. Cell Mol Bioeng. 2014 Mar;7(1):1-14. doi: 10.1007/s12195-013-0317-4. Cell Mol Bioeng. 2014. PMID: 24563678 Free PMC article.
Factor XI contributes to myocardial ischemia-reperfusion injury in mice.
Lorentz CU, Verbout NG, Cao Z, Liu L, Hinds MT, McCarty OJT, Ivanov I, Tucker EI, Gailani D, Gruber A. Lorentz CU, et al. Among authors: hinds mt. Blood Adv. 2018 Jan 23;2(2):85-88. doi: 10.1182/bloodadvances.2017004879. Blood Adv. 2018. PMID: 29365314 Free PMC article.
Protease-activated receptor 4 activity promotes platelet granule release and platelet-leukocyte interactions.
Rigg RA, Healy LD, Chu TT, Ngo ATP, Mitrugno A, Zilberman-Rudenko J, Aslan JE, Hinds MT, Vecchiarelli LD, Morgan TK, Gruber A, Temple KJ, Lindsley CW, Duvernay MT, Hamm HE, McCarty OJT. Rigg RA, et al. Among authors: hinds mt. Platelets. 2019;30(1):126-135. doi: 10.1080/09537104.2017.1406076. Epub 2018 Dec 18. Platelets. 2019. PMID: 30560697 Free PMC article.
Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial.
Lorentz CU, Verbout NG, Wallisch M, Hagen MW, Shatzel JJ, Olson SR, Puy C, Hinds MT, McCarty OJT, Gailani D, Gruber A, Tucker EI. Lorentz CU, et al. Among authors: hinds mt. Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):799-809. doi: 10.1161/ATVBAHA.118.312328. Arterioscler Thromb Vasc Biol. 2019. PMID: 30700130 Free PMC article. Clinical Trial.
Endothelial PAI-1 (Plasminogen Activator Inhibitor-1) Blocks the Intrinsic Pathway of Coagulation, Inducing the Clearance and Degradation of FXIa (Activated Factor XI).
Puy C, Ngo ATP, Pang J, Keshari RS, Hagen MW, Hinds MT, Gailani D, Gruber A, Lupu F, McCarty OJT. Puy C, et al. Among authors: hinds mt. Arterioscler Thromb Vasc Biol. 2019 Jul;39(7):1390-1401. doi: 10.1161/ATVBAHA.119.312619. Epub 2019 May 23. Arterioscler Thromb Vasc Biol. 2019. PMID: 31242030 Free PMC article.
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