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838 results

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Page 1
Management of Metastatic Urothelial Carcinoma in Emerging Markets (EM): An Expert Opinion.
Soares A, Bourlon MT, Wong A, Joshi A, Jardim D, Korbenfeld E, Karak FE, Orlandi F, Sze H, Ansari J, Zarba J, Mansour MA, Manneh R, Thirumulai R, Tsai YC, Morsi WA, Powles T. Soares A, et al. Among authors: powles t. Clin Genitourin Cancer. 2024 Apr;22(2):467-475. doi: 10.1016/j.clgc.2024.01.001. Epub 2024 Jan 3. Clin Genitourin Cancer. 2024. PMID: 38228413 Free article. Review.
Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma.
Motzer RJ, Tannir NM, McDermott DF, Arén Frontera O, Melichar B, Choueiri TK, Plimack ER, Barthélémy P, Porta C, George S, Powles T, Donskov F, Neiman V, Kollmannsberger CK, Salman P, Gurney H, Hawkins R, Ravaud A, Grimm MO, Bracarda S, Barrios CH, Tomita Y, Castellano D, Rini BI, Chen AC, Mekan S, McHenry MB, Wind-Rotolo M, Doan J, Sharma P, Hammers HJ, Escudier B; CheckMate 214 Investigators. Motzer RJ, et al. Among authors: powles t. N Engl J Med. 2018 Apr 5;378(14):1277-1290. doi: 10.1056/NEJMoa1712126. Epub 2018 Mar 21. N Engl J Med. 2018. PMID: 29562145 Free PMC article. Clinical Trial.
Outcomes by Retrospective Eligibility for Maintenance Therapy of Patients With Advanced Urothelial Carcinoma: Post Hoc Analysis of the Phase 3 KEYNOTE-361 Trial.
Mamtani R, Matsubara N, Pino AM, Herranz UA, Şendur MAN, Gravis G, Huillard O, Lee HJ, Gafanov R, Joly F, Bedke J, Sella A, Chang YH, Imai K, Moreno BH, Xu JZ, Alva A, Powles T. Mamtani R, et al. Among authors: powles t. Clin Genitourin Cancer. 2024 Oct 28;23(1):102248. doi: 10.1016/j.clgc.2024.102248. Online ahead of print. Clin Genitourin Cancer. 2024. PMID: 39579409 Free article.
Molecular heterogeneity in urothelial carcinoma and determinants of clinical benefit to PD-L1 blockade.
Hamidi H, Senbabaoglu Y, Beig N, Roels J, Manuel C, Guan X, Koeppen H, Assaf ZJ, Nabet BY, Waddell A, Yuen K, Maund S, Sokol E, Giltnane JM, Schedlbauer A, Fuentes E, Cowan JD, Kadel EE 3rd, Degaonkar V, Andreev-Drakhlin A, Williams P, Carter C, Gupta S, Steinberg E, Loriot Y, Bellmunt J, Grivas P, Rosenberg J, van der Heijden MS, Galsky MD, Powles T, Mariathasan S, Banchereau R. Hamidi H, et al. Among authors: powles t. Cancer Cell. 2024 Nov 16:S1535-6108(24)00404-5. doi: 10.1016/j.ccell.2024.10.016. Online ahead of print. Cancer Cell. 2024. PMID: 39577421
Adapting the design of the ongoing RAMPART trial in response to external evidence: An example for trials which take many years to run and report.
Meade A, Frangou E, Choodari-Oskooei B, Larkin J, Powles T, Stewart GD, Albiges L, Bex A, Choueiri TK, Davis ID, Eisen T, Fielding A, Gedye C, Harrison DJ, Kaplan R, Mulhere S, Nathan P, Patel G, Patel J, Plant H, Ritchie A, Rush H, Shakeshaft C, Stockler MR, Suarez C, Thompson J, Thorogood N, Venugopal B, Parmar MKB. Meade A, et al. Among authors: powles t. Contemp Clin Trials Commun. 2024 Oct 18;42:101381. doi: 10.1016/j.conctc.2024.101381. eCollection 2024 Dec. Contemp Clin Trials Commun. 2024. PMID: 39555240 Free PMC article.
First and Second-line Treatments in Metastatic Renal Cell Carcinoma.
Barragan-Carrillo R, Saad E, Saliby RM, Sun M, Albiges L, Bex A, Heng D, Mejean A, Motzer RJ, Plimack ER, Powles T, Rini BI, Zhang T, Choueiri TK. Barragan-Carrillo R, et al. Among authors: powles t. Eur Urol. 2024 Nov 5:S0302-2838(24)02681-2. doi: 10.1016/j.eururo.2024.10.019. Online ahead of print. Eur Urol. 2024. PMID: 39505582 Review.
Association of Tumor Mutational Burden and PD-L1 with the Efficacy of Pembrolizumab with or without Chemotherapy versus Chemotherapy in Advanced Urothelial Carcinoma.
Fléchon A, Morales-Barrera R, Powles T, Alva A, Özgüroğlu M, Csöszi T, Loriot Y, Rodriguez-Vida A, Géczi L, Cheng SY, Fradet Y, Oudard S, Vulsteke C, Gunduz S, Mamtani R, Yu EY, Montesa Pino A, Anido U, Sendur MAN, Gravis G, Révész J, Kostorov V, Huillard O, Ma J, Rajasagi M, Vajdi A, Lunceford J, Cristescu R, Imai K, Homet Moreno B, Matsubara N. Fléchon A, et al. Among authors: powles t. Clin Cancer Res. 2024 Oct 30:OF1-OF12. doi: 10.1158/1078-0432.CCR-23-3518. Online ahead of print. Clin Cancer Res. 2024. PMID: 39475359
Efficacy and safety of pembrolizumab in patients with advanced urothelial carcinoma deemed potentially ineligible for platinum-containing chemotherapy: Post hoc analysis of KEYNOTE-052 and LEAP-011.
O'Donnell PH, Loriot Y, Csoszi T, Matsubara N, Shin SJ, Park SH, Atduev V, Gumus M, Karaca SB, Grivas P, de Wit R, Castellano DE, Powles T, Vuky J, Zhao Y, O'Hara K, Okpara CE, Franco S, Homet Moreno B, Żołnierek J, Siefker-Radtke AO. O'Donnell PH, et al. Among authors: powles t. Cancer. 2024 Oct 28. doi: 10.1002/cncr.35601. Online ahead of print. Cancer. 2024. PMID: 39465550
Neoadjuvant and Adjuvant Immune-based Approach for Renal Cell Carcinoma: Pros, Cons, and Future Directions.
Marandino L, Campi R, Amparore D, Tippu Z, Albiges L, Capitanio U, Giles RH, Gillessen S, Kutikov A, Larkin J, Motzer RJ, Pierorazio PM, Powles T, Roupret M, Stewart GD, Turajlic S, Bex A. Marandino L, et al. Among authors: powles t. Eur Urol Oncol. 2024 Sep 25:S2588-9311(24)00211-6. doi: 10.1016/j.euo.2024.09.002. Online ahead of print. Eur Urol Oncol. 2024. PMID: 39327187 Free article. Review.
838 results