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Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.
ACS Chem Biol. 2024 Feb 16;19(2):563-574. doi: 10.1021/acschembio.3c00720. Epub 2024 Jan 17.
ACS Chem Biol. 2024.
PMID: 38232960
Free PMC article.
Targeting EPHA2 with Kinase Inhibitors in Colorectal Cancer.
Tröster A, Jores N, Mineev KS, Sreeramulu S, DiPrima M, Tosato G, Schwalbe H.
Tröster A, et al. Among authors: jores n.
ChemMedChem. 2023 Dec 1;18(23):e202300420. doi: 10.1002/cmdc.202300420. Epub 2023 Oct 5.
ChemMedChem. 2023.
PMID: 37736700
Free PMC article.
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Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor.
Tröster A, DiPrima M, Jores N, Kudlinzki D, Sreeramulu S, Gande SL, Linhard V, Ludig D, Schug A, Saxena K, Reinecke M, Heinzlmeir S, Leisegang MS, Wollenhaupt J, Lennartz F, Weiss MS, Kuster B, Tosato G, Schwalbe H.
Tröster A, et al. Among authors: jores n.
Chemistry. 2023 Apr 21;29(23):e202203967. doi: 10.1002/chem.202203967. Epub 2023 Mar 22.
Chemistry. 2023.
PMID: 36799129
Free PMC article.
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Mechanistic Impact of Different Ligand Scaffolds on FXR Modulation Suggests Avenues to Selective Modulators.
Heering J, Jores N, Kilu W, Schallmayer E, Peelen E, Muehler A, Kohlhof H, Vitt D, Linhard V, Gande SL, Chaikuad A, Sreeramulu S, Schwalbe H, Merk D.
Heering J, et al. Among authors: jores n.
ACS Chem Biol. 2022 Nov 18;17(11):3159-3168. doi: 10.1021/acschembio.2c00599. Epub 2022 Nov 1.
ACS Chem Biol. 2022.
PMID: 36318238
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