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Page 1
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements.
Scholz M, Horn K, Pott J, Wuttke M, Kühnapfel A, Nasr MK, Kirsten H, Li Y, Hoppmann A, Gorski M, Ghasemi S, Li M, Tin A, Chai JF, Cocca M, Wang J, Nutile T, Akiyama M, Åsvold BO, Bansal N, Biggs ML, Boutin T, Brenner H, Brumpton B, Burkhardt R, Cai J, Campbell A, Campbell H, Chalmers J, Chasman DI, Chee ML, Chee ML, Chen X, Cheng CY, Cifkova R, Daviglus M, Delgado G, Dittrich K, Edwards TL, Endlich K, Michael Gaziano J, Giri A, Giulianini F, Gordon SD, Gudbjartsson DF, Hallan S, Hamet P, Hartman CA, Hayward C, Heid IM, Hellwege JN, Holleczek B, Holm H, Hutri-Kähönen N, Hveem K, Isermann B, Jonas JB, Joshi PK, Kamatani Y, Kanai M, Kastarinen M, Khor CC, Kiess W, Kleber ME, Körner A, Kovacs P, Krajcoviechova A, Kramer H, Krämer BK, Kuokkanen M, Kähönen M, Lange LA, Lash JP, Lehtimäki T, Li H, Lin BM, Liu J, Loeffler M, Lyytikäinen LP, Magnusson PKE, Martin NG, Matsuda K, Milaneschi Y, Mishra PP, Mononen N, Montgomery GW, Mook-Kanamori DO, Mychaleckyj JC, März W, Nauck M, Nikus K, Nolte IM, Noordam R, Okada Y, Olafsson I, Oldehinkel AJ, Penninx BWJH, Perola M, Pirastu N, Polasek O, Porteous DJ, Poulain T, Psaty BM, Rabelink TJ, Raffield LM, Raitakari OT, Rasheed H, Reilly DF, Rice KM… See abstract for full author list ➔ Scholz M, et al. Among authors: ridker pm. Nat Commun. 2024 Jan 18;15(1):586. doi: 10.1038/s41467-024-44709-1. Nat Commun. 2024. PMID: 38233393 Free PMC article.
Meta-analysis of correlated traits via summary statistics from GWASs with an application in hypertension.
Zhu X, Feng T, Tayo BO, Liang J, Young JH, Franceschini N, Smith JA, Yanek LR, Sun YV, Edwards TL, Chen W, Nalls M, Fox E, Sale M, Bottinger E, Rotimi C; COGENT BP Consortium; Liu Y, McKnight B, Liu K, Arnett DK, Chakravati A, Cooper RS, Redline S. Zhu X, et al. Am J Hum Genet. 2015 Jan 8;96(1):21-36. doi: 10.1016/j.ajhg.2014.11.011. Epub 2014 Dec 11. Am J Hum Genet. 2015. PMID: 25500260 Free PMC article.
Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.
Keaton JM, Kamali Z, Xie T, Vaez A, Williams A, Goleva SB, Ani A, Evangelou E, Hellwege JN, Yengo L, Young WJ, Traylor M, Giri A, Zheng Z, Zeng J, Chasman DI, Morris AP, Caulfield MJ, Hwang SJ, Kooner JS, Conen D, Attia JR, Morrison AC, Loos RJF, Kristiansson K, Schmidt R, Hicks AA, Pramstaller PP, Nelson CP, Samani NJ, Risch L, Gyllensten U, Melander O, Riese H, Wilson JF, Campbell H, Rich SS, Psaty BM, Lu Y, Rotter JI, Guo X, Rice KM, Vollenweider P, Sundström J, Langenberg C, Tobin MD, Giedraitis V, Luan J, Tuomilehto J, Kutalik Z, Ripatti S, Salomaa V, Girotto G, Trompet S, Jukema JW, van der Harst P, Ridker PM, Giulianini F, Vitart V, Goel A, Watkins H, Harris SE, Deary IJ, van der Most PJ, Oldehinkel AJ, Keavney BD, Hayward C, Campbell A, Boehnke M, Scott LJ, Boutin T, Mamasoula C, Järvelin MR, Peters A, Gieger C, Lakatta EG, Cucca F, Hui J, Knekt P, Enroth S, De Borst MH, Polašek O, Concas MP, Catamo E, Cocca M, Li-Gao R, Hofer E, Schmidt H, Spedicati B, Waldenberger M, Strachan DP, Laan M, Teumer A, Dörr M, Gudnason V, Cook JP, Ruggiero D, Kolcic I, Boerwinkle E, Traglia M, Lehtimäki T, Raitakari OT, Johnson AD, Newton-Cheh C, Brown MJ, Dominiczak AF, Sever PJ, Poul… See abstract for full author list ➔ Keaton JM, et al. Among authors: ridker pm. Nat Genet. 2024 May;56(5):778-791. doi: 10.1038/s41588-024-01714-w. Epub 2024 Apr 30. Nat Genet. 2024. PMID: 38689001 Free PMC article.
Warfarin Dosing in Patients With CYP2C9*5 Variant Alleles.
Lindley KJ, Limdi NA, Cavallari LH, Perera MA, Lenzini P, Johnson JA, Wu AHB, Ridker PM, King CR, Eby CS, Patel S, Shah SV, Beasley TM, Li J, Gage BF. Lindley KJ, et al. Among authors: ridker pm. Clin Pharmacol Ther. 2022 Apr;111(4):950-955. doi: 10.1002/cpt.2549. Epub 2022 Feb 27. Clin Pharmacol Ther. 2022. PMID: 35108398
Gamma-glutamyl carboxylase and its influence on warfarin dose.
King CR, Deych E, Milligan P, Eby C, Lenzini P, Grice G, Porche-Sorbet RM, Ridker PM, Gage BF. King CR, et al. Among authors: ridker pm. Thromb Haemost. 2010 Oct;104(4):750-4. doi: 10.1160/TH09-11-0763. Epub 2010 Aug 5. Thromb Haemost. 2010. PMID: 20694283 Free PMC article.
Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL.
Vaisar T, Pennathur S, Green PS, Gharib SA, Hoofnagle AN, Cheung MC, Byun J, Vuletic S, Kassim S, Singh P, Chea H, Knopp RH, Brunzell J, Geary R, Chait A, Zhao XQ, Elkon K, Marcovina S, Ridker P, Oram JF, Heinecke JW. Vaisar T, et al. J Clin Invest. 2007 Mar;117(3):746-56. doi: 10.1172/JCI26206. J Clin Invest. 2007. PMID: 17332893 Free PMC article.
Lessons Learned from National Heart, Lung, and Blood Institute Covid-19 Clinical Trials.
Thomas SM, Harrington RA, Yancy CW, Nugent D, Erzurum S, Bernard GR, Cushman M, Hochman JS, Ridker PM, Ortel TL, Collins SP, Callaway CW, Nolen TL, Womack KN, Brown SM, Gelijns A, Geraci M, Ginde AA, Key NS, Krishnan JA, LaVange L, Wisniewski SR, Berdan L, Punturieri A, Goff DC, Patterson AP. Thomas SM, et al. Among authors: ridker pm. NEJM Evid. 2024 Nov;3(11):EVIDctcs2300291. doi: 10.1056/EVIDctcs2300291. Epub 2024 Oct 22. NEJM Evid. 2024. PMID: 39437132
Brief Report: Low-Dose Methotrexate Does Not Affect Measures of HIV-1 Persistence in Individuals With Chronically Treated HIV-1 Infection.
Cyktor JC, Yeh E, Ribaudo H, Hoeth D, Naqvi A, Bell T, Ridker PM, Fichtenbaum C, Daar ES, Havlir D, Tawakol A, Lederman MM, Stein JH, Deeks SG, Currier JS, Hsue PY, Mellors JW; A5314 Team. Cyktor JC, et al. Among authors: ridker pm. J Acquir Immune Defic Syndr. 2024 Aug 15;96(5):481-485. doi: 10.1097/QAI.0000000000003453. J Acquir Immune Defic Syndr. 2024. PMID: 39287554 Clinical Trial.
1,160 results