Thomas R - Search Results

1

High-Throughput Transcriptomics of Water Extracts Detects Reductions in Biological Activity with Water Treatment Processes.

Rogers JD, Leusch FDL, Chambers B, Daniels KD, Everett LJ, Judson R, Maruya K, Mehinto AC, Neale PA, Paul-Friedman K, Thomas R, Snyder SA, Harrill J. Rogers JD, et al. Among authors: thomas r. Environ Sci Technol. 2024 Jan 30;58(4):2027-2037. doi: 10.1021/acs.est.3c07525. Epub 2024 Jan 18. Environ Sci Technol. 2024. PMID: 38235672

2

Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.

Rotroff DM, Wetmore BA, Dix DJ, Ferguson SS, Clewell HJ, Houck KA, Lecluyse EL, Andersen ME, Judson RS, Smith CM, Sochaski MA, Kavlock RJ, Boellmann F, Martin MT, Reif DM, Wambaugh JF, Thomas RS. Rotroff DM, et al. Toxicol Sci. 2010 Oct;117(2):348-58. doi: 10.1093/toxsci/kfq220. Epub 2010 Jul 16. Toxicol Sci. 2010. PMID: 20639261 Free PMC article.

3

Estimating toxicity-related biological pathway altering doses for high-throughput chemical risk assessment.

Judson RS, Kavlock RJ, Setzer RW, Hubal EA, Martin MT, Knudsen TB, Houck KA, Thomas RS, Wetmore BA, Dix DJ. Judson RS, et al. Among authors: thomas rs. Chem Res Toxicol. 2011 Apr 18;24(4):451-62. doi: 10.1021/tx100428e. Epub 2011 Mar 8. Chem Res Toxicol. 2011. PMID: 21384849

4

Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment.

Wetmore BA, Wambaugh JF, Ferguson SS, Sochaski MA, Rotroff DM, Freeman K, Clewell HJ 3rd, Dix DJ, Andersen ME, Houck KA, Allen B, Judson RS, Singh R, Kavlock RJ, Richard AM, Thomas RS. Wetmore BA, et al. Among authors: thomas rs. Toxicol Sci. 2012 Jan;125(1):157-74. doi: 10.1093/toxsci/kfr254. Epub 2011 Sep 26. Toxicol Sci. 2012. PMID: 21948869

5

Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays.

Wetmore BA, Wambaugh JF, Ferguson SS, Li L, Clewell HJ 3rd, Judson RS, Freeman K, Bao W, Sochaski MA, Chu TM, Black MB, Healy E, Allen B, Andersen ME, Wolfinger RD, Thomas RS. Wetmore BA, et al. Toxicol Sci. 2013 Apr;132(2):327-46. doi: 10.1093/toxsci/kft012. Epub 2013 Jan 28. Toxicol Sci. 2013. PMID: 23358191

6

In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme.

Judson R, Houck K, Martin M, Knudsen T, Thomas RS, Sipes N, Shah I, Wambaugh J, Crofton K. Judson R, et al. Among authors: thomas rs. Basic Clin Pharmacol Toxicol. 2014 Jul;115(1):69-76. doi: 10.1111/bcpt.12239. Epub 2014 Apr 22. Basic Clin Pharmacol Toxicol. 2014. PMID: 24684691 Free article. Review.

7

Lineage-dependent effects of aryl hydrocarbon receptor agonists contribute to liver tumorigenesis.

Harrill JA, Parks BB, Wauthier E, Rowlands JC, Reid LM, Thomas RS. Harrill JA, et al. Hepatology. 2015 Feb;61(2):548-60. doi: 10.1002/hep.27547. Epub 2015 Jan 5. Hepatology. 2015. PMID: 25284723 Free PMC article.

8

Predicting hepatotoxicity using ToxCast in vitro bioactivity and chemical structure.

Liu J, Mansouri K, Judson RS, Martin MT, Hong H, Chen M, Xu X, Thomas RS, Shah I. Liu J, et al. Chem Res Toxicol. 2015 Apr 20;28(4):738-51. doi: 10.1021/tx500501h. Epub 2015 Mar 9. Chem Res Toxicol. 2015. PMID: 25697799

9

Screening Chemicals for Estrogen Receptor Bioactivity Using a Computational Model.

Browne P, Judson RS, Casey WM, Kleinstreuer NC, Thomas RS. Browne P, et al. Environ Sci Technol. 2015 Jul 21;49(14):8804-14. doi: 10.1021/acs.est.5b02641. Epub 2015 Jun 26. Environ Sci Technol. 2015. PMID: 26066997

10

Toxicokinetic Triage for Environmental Chemicals.

Wambaugh JF, Wetmore BA, Pearce R, Strope C, Goldsmith R, Sluka JP, Sedykh A, Tropsha A, Bosgra S, Shah I, Judson R, Thomas RS, Setzer RW. Wambaugh JF, et al. Among authors: thomas rs. Toxicol Sci. 2015 Sep;147(1):55-67. doi: 10.1093/toxsci/kfv118. Epub 2015 Jun 16. Toxicol Sci. 2015. PMID: 26085347 Free PMC article.

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