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Page 1
Design, Synthesis, and In Vitro and In Vivo Evaluation of Cereblon Binding Bruton's Tyrosine Kinase (BTK) Degrader CD79b Targeted Antibody-Drug Conjugates.
Zhang A, Seiss K, Laborde L, Palacio-Ramirez S, Guthy D, Lanter M, Lorber J, Vulpetti A, Arista L, Zoller T, Radimerski T, Thoma C, Hebach C, Tschantz WR, Karpov A, Hollingworth GJ, D'Alessio JA, Ferretti S, Burger MT. Zhang A, et al. Among authors: arista l. Bioconjug Chem. 2024 Feb 21;35(2):140-146. doi: 10.1021/acs.bioconjchem.3c00535. Epub 2024 Jan 24. Bioconjug Chem. 2024. PMID: 38265691
Discovery of a novel 2-aminopyrazine-3-carboxamide as a potent and selective inhibitor of Activin Receptor-Like Kinase-2 (ALK2) for the treatment of fibrodysplasia ossificans progressiva.
Ullrich T, Arista L, Weiler S, Teixeira-Fouchard S, Broennimann V, Stiefl N, Head V, Kramer I, Guth S. Ullrich T, et al. Among authors: arista l. Bioorg Med Chem Lett. 2022 May 15;64:128667. doi: 10.1016/j.bmcl.2022.128667. Epub 2022 Mar 8. Bioorg Med Chem Lett. 2022. PMID: 35276359
Multifunctional Carrier Based on Halloysite/Laponite Hybrid Hydrogel for Kartogenin Delivery.
Massaro M, Buscemi G, Arista L, Biddeci G, Cavallaro G, D'Anna F, Di Blasi F, Ferrante A, Lazzara G, Rizzo C, Spinelli G, Ullrich T, Riela S. Massaro M, et al. Among authors: arista l. ACS Med Chem Lett. 2018 Oct 22;10(4):419-424. doi: 10.1021/acsmedchemlett.8b00465. eCollection 2019 Apr 11. ACS Med Chem Lett. 2018. PMID: 30996773 Free PMC article.
Pyrrolo[3,4-c]pyridine-1,3(2H)-diones: A Novel Antimycobacterial Class Targeting Mycobacterial Respiration.
van der Westhuyzen R, Winks S, Wilson CR, Boyle GA, Gessner RK, Soares de Melo C, Taylor D, de Kock C, Njoroge M, Brunschwig C, Lawrence N, Rao SP, Sirgel F, van Helden P, Seldon R, Moosa A, Warner DF, Arista L, Manjunatha UH, Smith PW, Street LJ, Chibale K. van der Westhuyzen R, et al. Among authors: arista l. J Med Chem. 2015 Dec 10;58(23):9371-81. doi: 10.1021/acs.jmedchem.5b01542. Epub 2015 Nov 20. J Med Chem. 2015. PMID: 26551248
Exploration of the amine terminus in a novel series of 1,2,4-triazolo-3-yl-azabicyclo[3.1.0]hexanes as selective dopamine D3 receptor antagonists.
Micheli F, Arista L, Bertani B, Braggio S, Capelli AM, Cremonesi S, Di-Fabio R, Gelardi G, Gentile G, Marchioro C, Pasquarello A, Provera S, Tedesco G, Tarsi L, Terreni S, Worby A, Heidbreder C. Micheli F, et al. Among authors: arista l. J Med Chem. 2010 Oct 14;53(19):7129-39. doi: 10.1021/jm100832d. J Med Chem. 2010. PMID: 20839775
The identification of a selective dopamine D2 partial agonist, D3 antagonist displaying high levels of brain exposure.
Holmes IP, Blunt RJ, Lorthioir OE, Blowers SM, Gribble A, Payne AH, Stansfield IG, Wood M, Woollard PM, Reavill C, Howes CM, Micheli F, Di Fabio R, Donati D, Terreni S, Hamprecht D, Arista L, Worby A, Watson SP. Holmes IP, et al. Among authors: arista l. Bioorg Med Chem Lett. 2010 Mar 15;20(6):2013-6. doi: 10.1016/j.bmcl.2010.01.090. Epub 2010 Jan 25. Bioorg Med Chem Lett. 2010. PMID: 20153647
1,2,4-Triazolyl azabicyclo[3.1.0]hexanes: a new series of potent and selective dopamine D(3) receptor antagonists.
Micheli F, Arista L, Bonanomi G, Blaney FE, Braggio S, Capelli AM, Checchia A, Damiani F, Di-Fabio R, Fontana S, Gentile G, Griffante C, Hamprecht D, Marchioro C, Mugnaini M, Piner J, Ratti E, Tedesco G, Tarsi L, Terreni S, Worby A, Ashby CR Jr, Heidbreder C. Micheli F, et al. Among authors: arista l. J Med Chem. 2010 Jan 14;53(1):374-91. doi: 10.1021/jm901319p. J Med Chem. 2010. PMID: 19891474
Dopamine D(3) receptor antagonists: The quest for a potentially selective PET ligand. Part two: Lead optimization.
Micheli F, Holmes I, Arista L, Bonanomi G, Braggio S, Cardullo F, Di Fabio R, Donati D, Gentile G, Hamprecht D, Terreni S, Heidbreder C, Savoia C, Griffante C, Worby A. Micheli F, et al. Among authors: arista l. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4011-3. doi: 10.1016/j.bmcl.2009.06.028. Epub 2009 Jun 13. Bioorg Med Chem Lett. 2009. PMID: 19553113