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Head-to-head comparison of [18F]-Flortaucipir, [18F]-MK-6240 and [18F]-PI-2620 postmortem binding across the spectrum of neurodegenerative diseases.
Aguero C, Dhaynaut M, Amaral AC, Moon SH, Neelamegam R, Scapellato M, Carazo-Casas C, Kumar S, El Fakhri G, Johnson K, Frosch MP, Normandin MD, Gómez-Isla T. Aguero C, et al. Among authors: amaral ac. Acta Neuropathol. 2024 Jan 27;147(1):25. doi: 10.1007/s00401-023-02672-z. Acta Neuropathol. 2024. PMID: 38280071 Free PMC article.
[F-18]-AV-1451 binding correlates with postmortem neurofibrillary tangle Braak staging.
Marquié M, Siao Tick Chong M, Antón-Fernández A, Verwer EE, Sáez-Calveras N, Meltzer AC, Ramanan P, Amaral AC, Gonzalez J, Normandin MD, Frosch MP, Gómez-Isla T. Marquié M, et al. Among authors: amaral ac. Acta Neuropathol. 2017 Oct;134(4):619-628. doi: 10.1007/s00401-017-1740-8. Epub 2017 Jun 13. Acta Neuropathol. 2017. PMID: 28612291 Free PMC article.
Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson's case.
Marquié M, Verwer EE, Meltzer AC, Kim SJW, Agüero C, Gonzalez J, Makaretz SJ, Siao Tick Chong M, Ramanan P, Amaral AC, Normandin MD, Vanderburg CR, Gomperts SN, Johnson KA, Frosch MP, Gómez-Isla T. Marquié M, et al. Among authors: amaral ac. Acta Neuropathol Commun. 2017 Oct 19;5(1):75. doi: 10.1186/s40478-017-0482-0. Acta Neuropathol Commun. 2017. PMID: 29047416 Free PMC article.
Distinct cytokine profiles in human brains resilient to Alzheimer's pathology.
Barroeta-Espar I, Weinstock LD, Perez-Nievas BG, Meltzer AC, Siao Tick Chong M, Amaral AC, Murray ME, Moulder KL, Morris JC, Cairns NJ, Parisi JE, Lowe VJ, Petersen RC, Kofler J, Ikonomovic MD, López O, Klunk WE, Mayeux RP, Frosch MP, Wood LB, Gomez-Isla T. Barroeta-Espar I, et al. Among authors: amaral ac. Neurobiol Dis. 2019 Jan;121:327-337. doi: 10.1016/j.nbd.2018.10.009. Epub 2018 Oct 15. Neurobiol Dis. 2019. PMID: 30336198 Free PMC article.
[18F]-AV-1451 binding profile in chronic traumatic encephalopathy: a postmortem case series.
Marquié M, Agüero C, Amaral AC, Villarejo-Galende A, Ramanan P, Chong MST, Sáez-Calveras N, Bennett RE, Verwer EE, Kim SJW, Dhaynaut M, Alvarez VE, Johnson KA, McKee AC, Frosch MP, Gómez-Isla T. Marquié M, et al. Among authors: amaral ac. Acta Neuropathol Commun. 2019 Oct 28;7(1):164. doi: 10.1186/s40478-019-0808-1. Acta Neuropathol Commun. 2019. PMID: 31661038 Free PMC article.
Isoform-selective decrease of glycogen synthase kinase-3-beta (GSK-3β) reduces synaptic tau phosphorylation, transcellular spreading, and aggregation.
Amaral AC, Perez-Nievas BG, Siao Tick Chong M, Gonzalez-Martinez A, Argente-Escrig H, Rubio-Guerra S, Commins C, Muftu S, Eftekharzadeh B, Hudry E, Fan Z, Ramanan P, Takeda S, Frosch MP, Wegmann S, Gomez-Isla T. Amaral AC, et al. iScience. 2021 Jan 13;24(2):102058. doi: 10.1016/j.isci.2021.102058. eCollection 2021 Feb 19. iScience. 2021. PMID: 33554064 Free PMC article.
Experimental evidence for the age dependence of tau protein spread in the brain.
Wegmann S, Bennett RE, Delorme L, Robbins AB, Hu M, McKenzie D, Kirk MJ, Schiantarelli J, Tunio N, Amaral AC, Fan Z, Nicholls S, Hudry E, Hyman BT. Wegmann S, et al. Among authors: amaral ac. Sci Adv. 2019 Jun 26;5(6):eaaw6404. doi: 10.1126/sciadv.aaw6404. eCollection 2019 Jun. Sci Adv. 2019. PMID: 31249873 Free PMC article.
Novel genetic variants in MAPT and alterations in tau phosphorylation in amyotrophic lateral sclerosis post-mortem motor cortex and cerebrospinal fluid.
Petrozziello T, Amaral AC, Dujardin S, Farhan SMK, Chan J, Trombetta BA, Kivisäkk P, Mills AN, Bordt EA, Kim SE, Dooley PM, Commins C, Connors TR, Oakley DH, Ghosal A, Gomez-Isla T, Hyman BT, Arnold SE, Spires-Jones T, Cudkowicz ME, Berry JD, Sadri-Vakili G. Petrozziello T, et al. Among authors: amaral ac. Brain Pathol. 2022 Mar;32(2):e13035. doi: 10.1111/bpa.13035. Epub 2021 Nov 14. Brain Pathol. 2022. PMID: 34779076 Free PMC article.
258 results