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Safety and efficacy of laquinimod for Huntington's disease (LEGATO-HD): a multicentre, randomised, double-blind, placebo-controlled, phase 2 study.
Reilmann R, Anderson KE, Feigin A, Tabrizi SJ, Leavitt BR, Stout JC, Piccini P, Schubert R, Loupe P, Wickenberg A, Borowsky B, Rynkowski G, Volkinshtein R, Li T, Savola JM, Hayden M, Gordon MF; LEGATO-HD Study Group. Reilmann R, et al. Among authors: li t. Lancet Neurol. 2024 Mar;23(3):243-255. doi: 10.1016/S1474-4422(23)00454-4. Epub 2024 Jan 24. Lancet Neurol. 2024. PMID: 38280392 Clinical Trial.
IMI2-PainCare-BioPain-RCT2 protocol: a randomized, double-blind, placebo-controlled, crossover, multicenter trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by non-invasive neurophysiological measurements of human spinal cord and brainstem activity.
Leone C, Di Stefano G, Di Pietro G, Bloms-Funke P, Boesl I, Caspani O, Chapman SC, Finnerup NB, Garcia-Larrea L, Li T, Goetz M, Mouraux A, Pelz B, Pogatzki-Zahn E, Schilder A, Schnetter E, Schubart K, Tracey I, Troconiz IF, Van Niel H, Hernandez JMV, Vincent K, Vollert J, Wanigasekera V, Wittayer M, Phillips KG, Truini A, Treede RD. Leone C, et al. Among authors: li t. Trials. 2022 Sep 5;23(1):739. doi: 10.1186/s13063-022-06431-5. Trials. 2022. PMID: 36064434 Free PMC article.
IMI2-PainCare-BioPain-RCT1: study protocol for a randomized, double-blind, placebo-controlled, crossover, multi-center trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by peripheral nerve excitability testing (NET).
Nochi Z, Pia H, Bloms-Funke P, Boesl I, Caspani O, Chapman SC, Fardo F, Genser B, Goetz M, Kostenko AV, Leone C, Li T, Mouraux A, Pelz B, Pogatzki-Zahn E, Schilder A, Schnetter E, Schubart K, Stouffs A, Tracey I, Troconiz IF, Truini A, Van Niel J, Vela JM, Vincent K, Vollert J, Wanigasekera V, Wittayer M, Tankisi H, Finnerup NB, Phillips KG, Treede RD. Nochi Z, et al. Among authors: li t. Trials. 2022 Feb 19;23(1):163. doi: 10.1186/s13063-022-06087-1. Trials. 2022. PMID: 35183242 Free PMC article.
A novel Y-shaped pegylated recombinant human growth hormone for children with growth hormone deficiency: a phase 3 study.
Liang Y, Wei H, Yang F, Zhang H, Chen L, Yao H, Luo X, Cheng X, Yang Y, Lian Q, Du H, Li T, Li P, Zhang G, Song F, Liang L, Liu D, Zhu S, Gong H, Gong C, Cheng X, Xu Z, Ma Y, Su Z, Zhou W, He R, Yin Y, Sun L, Luo X. Liang Y, et al. Among authors: li t. J Clin Endocrinol Metab. 2024 Nov 28:dgae816. doi: 10.1210/clinem/dgae816. Online ahead of print. J Clin Endocrinol Metab. 2024. PMID: 39607675
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