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PD-1 checkpoint inhibition enhances the antilymphoma activity of CD19-CAR-iNKT cells that retain their ability to prevent alloreactivity.
Moraes Ribeiro E, Secker KA, Nitulescu AM, Schairer R, Keppeler H, Wesle A, Schmid H, Schmitt A, Neuber B, Chmiest D, Podavini S, Märklin M, Klimovich B, Schmitt M, Korkmaz F, Lengerke C, Schneidawind C, Schneidawind D. Moraes Ribeiro E, et al. Among authors: keppeler h. J Immunother Cancer. 2024 Jan 31;12(1):e007829. doi: 10.1136/jitc-2023-007829. J Immunother Cancer. 2024. PMID: 38296597 Free PMC article.
Antifibrotic effects of CXCL9 and its receptor CXCR3 in livers of mice and humans.
Wasmuth HE, Lammert F, Zaldivar MM, Weiskirchen R, Hellerbrand C, Scholten D, Berres ML, Zimmermann H, Streetz KL, Tacke F, Hillebrandt S, Schmitz P, Keppeler H, Berg T, Dahl E, Gassler N, Friedman SL, Trautwein C. Wasmuth HE, et al. Among authors: keppeler h. Gastroenterology. 2009 Jul;137(1):309-19, 319.e1-3. doi: 10.1053/j.gastro.2009.03.053. Epub 2009 Apr 1. Gastroenterology. 2009. PMID: 19344719 Free PMC article.
Invariant NKT Cells From Donor Lymphocyte Infusions (DLI-iNKTs) Promote ex vivo Lysis of Leukemic Blasts in a CD1d-Dependent Manner.
Jahnke S, Schmid H, Secker KA, Einhaus J, Duerr-Stoerzer S, Keppeler H, Schober-Melms I, Baur R, Schumm M, Handgretinger R, Bethge W, Kanz L, Schneidawind C, Schneidawind D. Jahnke S, et al. Among authors: keppeler h. Front Immunol. 2019 Jul 9;10:1542. doi: 10.3389/fimmu.2019.01542. eCollection 2019. Front Immunol. 2019. PMID: 31354710 Free PMC article.
Inhibition of effector B cells by ibrutinib in systemic sclerosis.
Einhaus J, Pecher AC, Asteriti E, Schmid H, Secker KA, Duerr-Stoerzer S, Keppeler H, Klein R, Schneidawind C, Henes J, Schneidawind D. Einhaus J, et al. Among authors: keppeler h. Arthritis Res Ther. 2020 Mar 30;22(1):66. doi: 10.1186/s13075-020-02153-8. Arthritis Res Ther. 2020. PMID: 32228672 Free PMC article.
46 results