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A Gamma-adapted subunit vaccine induces broadly neutralizing antibodies against SARS-CoV-2 variants and protects mice from infection.
Coria LM, Rodriguez JM, Demaria A, Bruno LA, Medrano MR, Castro CP, Castro EF, Del Priore SA, Hernando Insua AC, Kaufmann IG, Saposnik LM, Stone WB, Prado L, Notaro US, Amweg AN, Diaz PU, Avaro M, Ortega H, Ceballos A, Krum V, Zurvarra FM, Sidabra JE, Drehe I, Baqué JA, Li Causi M, De Nichilo AV, Payes CJ, Southard T, Vega JC, Auguste AJ, Álvarez DE, Flo JM, Pasquevich KA, Cassataro J. Coria LM, et al. Among authors: cassataro j. Nat Commun. 2024 Feb 2;15(1):997. doi: 10.1038/s41467-024-45180-8. Nat Commun. 2024. PMID: 38307851 Free PMC article.
Brucella lumazine synthase elicits a mixed Th1-Th2 immune response and reduces infection in mice challenged with Brucella abortus 544 independently of the adjuvant formulation used.
Velikovsky CA, Goldbaum FA, Cassataro J, Estein S, Bowden RA, Bruno L, Fossati CA, Giambartolomei GH. Velikovsky CA, et al. Among authors: cassataro j. Infect Immun. 2003 Oct;71(10):5750-5. doi: 10.1128/IAI.71.10.5750-5755.2003. Infect Immun. 2003. PMID: 14500496 Free PMC article.
Vaccination with the recombinant Brucella outer membrane protein 31 or a derived 27-amino-acid synthetic peptide elicits a CD4+ T helper 1 response that protects against Brucella melitensis infection.
Cassataro J, Estein SM, Pasquevich KA, Velikovsky CA, de la Barrera S, Bowden R, Fossati CA, Giambartolomei GH. Cassataro J, et al. Infect Immun. 2005 Dec;73(12):8079-88. doi: 10.1128/IAI.73.12.8079-8088.2005. Infect Immun. 2005. PMID: 16299302 Free PMC article.
A recombinant subunit vaccine based on the insertion of 27 amino acids from Omp31 to the N-terminus of BLS induced a similar degree of protection against B. ovis than Rev.1 vaccination.
Cassataro J, Pasquevich KA, Estein SM, Laplagne DA, Velikovsky CA, de la Barrera S, Bowden R, Fossati CA, Giambartolomei GH, Goldbaum FA. Cassataro J, et al. Vaccine. 2007 May 30;25(22):4437-46. doi: 10.1016/j.vaccine.2007.03.028. Epub 2007 Apr 2. Vaccine. 2007. PMID: 17442465
A DNA vaccine coding for the chimera BLSOmp31 induced a better degree of protection against B. ovis and a similar degree of protection against B. melitensis than Rev.1 vaccination.
Cassataro J, Pasquevich KA, Estein SM, Laplagne DA, Zwerdling A, de la Barrera S, Bowden R, Fossati CA, Giambartolomei GH, Goldbaum FA. Cassataro J, et al. Vaccine. 2007 Aug 10;25(32):5958-67. doi: 10.1016/j.vaccine.2007.05.049. Epub 2007 Jun 12. Vaccine. 2007. PMID: 17600596
64 results